FULC Stock - Fulcrum Therapeutics, Inc.
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Financial Statements
| Metric | FY2024 | FY2023 | FY2022 | FY2021 | FY2020 |
|---|---|---|---|---|---|
| Revenue | $80.00M | $2.81M | $6.34M | $19.16M | $8.82M |
| Gross Profit | $16.61M | $2.81M | $-70,440,000 | $-50,538,000 | $-50,219,000 |
| Gross Margin | 20.8% | 100.0% | -1110.7% | -263.7% | -569.2% |
| Operating Income | $-21,897,000 | $-110,664,000 | $-112,561,000 | $-81,054,000 | $-71,611,000 |
| Net Income | $-9,725,000 | $-97,335,000 | $-109,871,000 | $-80,847,000 | $-70,819,000 |
| Net Margin | -12.2% | -3470.1% | -1732.4% | -421.9% | -802.7% |
| EPS | $-0.16 | $-1.59 | $-2.35 | $-2.22 | $-2.70 |
Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing products for improving the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its product candidates are losmapimod, a small molecule for the treatment of facioscapulohumeral muscular dystrophy; and FTX-6058, an investigational oral fetal hemoglobin inducer for the treatment of sickle cell disease and other hemoglobinopathies, including beta-thalassemia. The company is also discovering drug targets for the treatments of rare neuromuscular, muscular, central nervous system, and hematologic disorders, as well as cardiomyopathies and pulmonary diseases. Fulcrum Therapeutics, Inc. has research and discovery collaboration agreement with Acceleron Pharma Inc. to identify biological targets to modulate specific pathways associated with a targeted indication within the pulmonary disease space; and has a strategic collaboration and license agreement with MyoKardia, Inc. to discover, develop, and commercialize novel targeted therapies for the treatment of genetic cardiomyopathies. Fulcrum Therapeutics, Inc. was Incorporated in 2015 and is headquartered in Cambridge, Massachusetts.
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Price Targets
Recent Analyst Actions
| Date | Firm | Action | Rating | Price Target |
|---|---|---|---|---|
| November 24th 2025 | Truist | Initiation | Buy | - |
| July 29th 2025 | H.C. Wainwright | Upgrade | Buy | $12← $4 |
| May 23rd 2025 | Leerink Partners | Upgrade | Outperform | $12 |
| May 15th 2025 | Cantor Fitzgerald | Upgrade | Overweight | $10 |
| September 13th 2024 | H.C. Wainwright | Downgrade | Neutral | $4← $17 |
| September 12th 2024 | RBC Capital Mkts | Downgrade | Sector Perform | $4← $15 |
| September 12th 2024 | Leerink Partners | Downgrade | Market Perform | $4 |
| September 12th 2024 | BofA Securities | Downgrade | Underperform | $2← $10 |
| September 12th 2024 | Stifel | Downgrade | Hold | - |
| September 12th 2024 | Cantor Fitzgerald | Downgrade | Neutral | - |
| September 9th 2024 | BofA Securities | Upgrade | Neutral | $10← $5 |
| May 20th 2024 | Cantor Fitzgerald | Initiation | Overweight | $23 |
| March 13th 2024 | RBC Capital Mkts | Initiation | Outperform | $14 |
| September 25th 2023 | Goldman | Initiation | Neutral | $5 |
| August 23rd 2023 | H.C. Wainwright | Upgrade | Buy | $14← $5 |
Earnings History & Surprises
FULCEPS Surprise History
Quarterly EPS Details
| Period | Report Date | Estimated EPS | Actual EPS | Surprise | Result |
|---|---|---|---|---|---|
Q2 2026 | Apr 29, 2026 | — | — | — | — |
Q1 2026 | Feb 24, 2026 | $-0.32 | — | — | — |
Q4 2025 | Oct 29, 2025 | $-0.29 | $-0.31 | -6.9% | ✗ MISS |
Q3 2025 | Jul 29, 2025 | $-0.29 | $-0.28 | +3.4% | ✓ BEAT |
Q2 2025 | May 1, 2025 | $-0.29 | $-0.28 | +3.4% | ✓ BEAT |
Q1 2025 | Feb 25, 2025 | $-0.28 | $-0.31 | -10.7% | ✗ MISS |
Q4 2024 | Nov 13, 2024 | $-0.40 | $-0.35 | +12.5% | ✓ BEAT |
Q3 2024 | Jul 31, 2024 | $0.01 | $0.87 | +7060.5% | ✓ BEAT |
Q2 2024 | May 13, 2024 | $-0.44 | $-0.43 | +2.3% | ✓ BEAT |
Q1 2024 | Feb 27, 2024 | $-0.44 | $-0.40 | +9.1% | ✓ BEAT |
Q4 2023 | Nov 7, 2023 | $-0.44 | $-0.39 | +11.4% | ✓ BEAT |
Q3 2023 | Aug 3, 2023 | $-0.44 | $-0.38 | +13.6% | ✓ BEAT |
Q2 2023 | Jun 23, 2023 | — | $-0.45 | — | — |
Q2 2023 | May 15, 2023 | $-0.47 | $-0.41 | +12.8% | ✓ BEAT |
Q4 2022 | Nov 8, 2022 | $-0.62 | $-0.50 | +19.4% | ✓ BEAT |
Q3 2022 | Aug 11, 2022 | $-0.66 | $-0.83 | -25.8% | ✗ MISS |
Q2 2022 | May 9, 2022 | $-0.63 | $-0.64 | -1.6% | ✗ MISS |
Q1 2022 | Mar 3, 2022 | $-0.65 | $-0.58 | +10.8% | ✓ BEAT |
Q4 2021 | Nov 4, 2021 | $-0.64 | $-0.57 | +10.9% | ✓ BEAT |
Q3 2021 | Aug 10, 2021 | $-0.65 | $-0.60 | +7.7% | ✓ BEAT |
Latest News
Truist Securities Maintains Buy on Fulcrum Therapeutics, Raises Price Target to $18
📈 PositiveFulcrum Therapeutics Prices $175M Public Offering of Common Stock And Pre‑Funded Warrants At $13.50
📉 NegativeB of A Securities Maintains Underperform on Fulcrum Therapeutics, Raises Price Target to $7
➖ NeutralFulcrum Therapeutics announces proposed $150.0 million public offering of common stock
➖ NeutralFulcrum Therapeutics Announces Proposed $150M Public Offering Of Common Stock
➖ NeutralRBC Capital Maintains Sector Perform on Fulcrum Therapeutics, Raises Price Target to $10
📈 PositiveCantor Fitzgerald Maintains Overweight on Fulcrum Therapeutics, Raises Price Target to $24
📈 PositivePiper Sandler Reiterates Overweight on Fulcrum Therapeutics, Raises Price Target to $23
📈 PositiveFulcrum Therapeutics shares are trading higher after the company reported initial results from the 20 mg dose cohort of its Phase 1b PIONEER trial of Pociredir in sickle cell disease, showing a clear dose-response and robust fetal hemoglobin induction at week 6.
📈 PositiveHC Wainwright & Co. Maintains Buy on Fulcrum Therapeutics, Raises Price Target to $25
📈 PositiveMarket-Moving News for December 8th
➖ NeutralFulcrum Therapeutics Announced Saturday, Initial Results From 20 mg Dose Cohort Of The Phase 1b PIONEER Trial Of Pociredir In Sickle Cell Disease; Clear Dose-response Observed, With Robust, Clinically Meaningful Fetal Hemoglobin Induction At Week 6 Timepoint
📈 PositiveTruist Securities Initiates Coverage On Fulcrum Therapeutics with Buy Rating, Announces Price Target of $14
📈 PositiveHC Wainwright & Co. Maintains Buy on Fulcrum Therapeutics, Raises Price Target to $18
📈 PositiveFulcrum Therapeutics To Present New Data From The Phase 1b PIONEER Trial Of Pociredir In Sickle Cell Disease (Scd) Will Be Presented At The 67th American Society Of Hematology Annual Meeting
📈 PositiveRBC Capital Maintains Sector Perform on Fulcrum Therapeutics, Raises Price Target to $7
➖ NeutralPiper Sandler Reiterates Overweight on Fulcrum Therapeutics, Raises Price Target to $16
📈 PositiveFulcrum Therapeutics Q3 EPS $(0.31) Misses $(0.29) Estimate; Cash $200.6M
📉 NegativeHC Wainwright & Co. Reiterates Buy on Fulcrum Therapeutics, Maintains $12 Price Target
📈 PositiveFulcrum Therapeutics to Present Preclinical Data on FTX-6274 for Advanced Prostate Cancer at ESMO 2025
➖ NeutralFrequently Asked Questions about FULC
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