SNTI Stock - Senti Biosciences, Inc.
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Financial Statements
| Metric | FY2024 | FY2023 | FY2022 | FY2021 | FY2020 |
|---|---|---|---|---|---|
| Revenue | N/A | $1.98M | $3.29M | $2.29M | $394,000 |
| Gross Profit | N/A | $1.98M | $3.29M | $2.29M | $394,000 |
| Gross Margin | N/A | 100.0% | 100.0% | 100.0% | 100.0% |
| Operating Income | $-61,039,000 | $-92,727,000 | $-62,084,000 | $-40,446,000 | $-24,694,000 |
| Net Income | $-52,790,000 | $-71,058,000 | $-58,210,000 | $-55,319,000 | $-19,862,000 |
| Net Margin | N/A | -3592.4% | -1771.5% | -2414.6% | -5041.1% |
| EPS | $-11.49 | $-20.94 | $-13.25 | $-12.67 | $-4.55 |
Senti Biosciences, Inc. operates as a gene circuit company. The company develops cell and gene therapies engineered with gene circuits that are designed to reprogram cells with biological logic to sense inputs, compute decisions, and respond to respective cellular environments. Its synthetic biology platform utilizes off-the-shelf chimeric antigen receptor natural killer (CAR-NK) cells to target particularly challenging liquid and solid tumor oncology indications. The company's lead programs include SENTI-202, a Logic Gated OR+NOT off-the-shelf CAR-NK cell therapy designed to target and eliminate acute myeloid leukemia (AML) cells, while sparing the healthy bone marrow; and SENTI-301, a multi-armed off-the-shelf CAR-NK cell therapy designed for the treatment of hepatocellular carcinoma (HCC). It also develops SENTI-401, a Logic Gated (NOT) off-the-shelf CAR-NK cell therapy designed to target and eliminate colorectal cancer (CRC) cells, while sparing healthy cells in the body. The company was founded in 2016 and is based in South San Francisco, California.
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Price Targets
Recent Analyst Actions
| Date | Firm | Action | Rating | Price Target |
|---|---|---|---|---|
| October 14th 2025 | H.C. Wainwright | Initiation | Buy | $12 |
| June 6th 2025 | Laidlaw | Initiation | Buy | $5 |
| October 7th 2022 | Morgan Stanley | Initiation | Equal Weight | $7.5 |
Earnings History & Surprises
SNTIEPS Surprise History
Quarterly EPS Details
| Period | Report Date | Estimated EPS | Actual EPS | Surprise | Result |
|---|---|---|---|---|---|
Q1 2026 | Mar 19, 2026 | $-0.43 | — | — | — |
Q4 2025 | Nov 13, 2025 | $-0.59 | $-0.69 | -16.9% | ✗ MISS |
Q3 2025 | Aug 7, 2025 | $-0.90 | $-0.56 | +37.8% | ✓ BEAT |
Q2 2025 | May 6, 2025 | $-0.58 | $-1.41 | -143.1% | ✗ MISS |
Q1 2025 | Mar 20, 2025 | $-3.13 | $-0.67 | +78.6% | ✓ BEAT |
Q4 2024 | Nov 14, 2024 | — | $-6.31 | — | — |
Q3 2024 | Aug 13, 2024 | — | $-2.45 | — | — |
Q2 2024 | May 9, 2024 | — | $-2.60 | — | — |
Q1 2024 | Mar 21, 2024 | $-0.23 | $-4.20 | -1726.1% | ✗ MISS |
Q4 2023 | Nov 13, 2023 | $-4.80 | $-2.50 | +47.9% | ✓ BEAT |
Q3 2023 | Aug 11, 2023 | $-4.80 | $-4.20 | +12.5% | ✓ BEAT |
Q2 2023 | May 9, 2023 | $-4.80 | $-4.20 | +12.5% | ✓ BEAT |
Q1 2023 | Mar 22, 2023 | $-4.70 | $-4.20 | +10.6% | ✓ BEAT |
Q4 2022 | Nov 10, 2022 | $-5.20 | $-3.80 | +26.9% | ✓ BEAT |
Q3 2022 | Aug 15, 2022 | — | $-2.65 | — | — |
Q3 2022 | Aug 9, 2022 | — | $-2.70 | — | — |
Q1 2022 | Mar 7, 2022 | — | $-2.50 | — | — |
Q4 2021 | Nov 10, 2021 | — | $-2.61 | — | — |
Q3 2021 | Aug 6, 2021 | — | $-2.75 | — | — |
Q3 2021 | Jul 2, 2021 | — | $-0.00 | — | — |
Latest News
Chardan Capital Maintains Buy on Senti Biosciences, Raises Price Target to $13
📈 PositiveSNTI stock has given up its prior gain. Senti Biosciences shares were trading higher after the company announced new data from its ongoing multinational, multicenter clinical trial of SENTI-202
➖ NeutralSenti Biosciences shares are trading higher after the company announced new data from its ongoing multinational, multicenter clinical trial of SENTI-202
📈 PositiveMarket-Moving News for December 9th
➖ NeutralSenti Biosciences Says FDA Grants Regenerative Medicine Advanced Therapy Designation To SENTI-202 For Treatment Of R/R Hematologic Malignancies, Including AML
📈 PositiveSenti Bio Receives FDA RMAT Designation For SENTI-202 In Relapsed Or Refractory AML After Orphan Drug Status, Backed By 50% ORR And 42% CR/CRh At RP2D
📈 PositiveSenti Bio Reports Updated Phase 1 SENTI-202 Data In R/R AML Showing 50% ORR, 42% CR/CRh With Mostly MRD-Negative Durable Responses And RMAT Support For Advancement Toward Pivotal Study
📈 PositiveLeerink Partners Initiates Coverage On Senti Biosciences with Outperform Rating, Announces Price Target of $6
📈 PositiveSenti Biosciences Q3 EPS $(0.69) Misses $(0.56) Estimate
📉 NegativeSenti Biosciences Says SENTI-202 Shows Deep, Durable Remissions In R/R AML With Selective Cancer Killing Ahead Of ASH 2025 Presentations
📈 PositiveHC Wainwright & Co. Initiates Coverage On Senti Biosciences with Buy Rating, Announces Price Target of $12
📈 PositiveFrequently Asked Questions about SNTI
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