VRTX Stock - Vertex Pharmaceuticals Incorporated
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Financial Statements
| Metric | FY2024 | FY2023 | FY2022 | FY2021 | FY2020 |
|---|---|---|---|---|---|
| Revenue | $11.02B | $9.87B | $8.93B | $7.57B | $6.21B |
| Gross Profit | $9.49B | $8.61B | $7.85B | $6.67B | $5.47B |
| Gross Margin | 86.1% | 87.2% | 87.9% | 88.1% | 88.1% |
| Operating Income | $-232,900,000 | $3.83B | $4.31B | $2.78B | $2.86B |
| Net Income | $-535,600,000 | $3.62B | $3.32B | $2.34B | $2.71B |
| Net Margin | -4.9% | 36.7% | 37.2% | 30.9% | 43.7% |
| EPS | $-2.08 | $14.05 | $12.97 | $9.09 | $10.44 |
Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis. The company markets SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO to treat patients with cystic fibrosis who have specific mutations in their cystic fibrosis transmembrane conductance regulator gene; and TRIKAFTA for the treatment of patients with CF 6 years of age or older who have at least one F508del mutation. Its pipeline includes VX-864 for the treatment of AAT deficiency, which is in Phase 2 clinical trial; VX-147 for the treatment of APOL1-mediated focal segmental glomerulosclerosis, or FSGS, and other serious kidney diseases which is in Phase 2 clinical trial; VX- 880, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-548, a NaV1.8 inhibitor for treatments of acute, neuropathic, musculoskeletal pain which is in Phase 2 clinical trial; and CTX001 for the treatment severe SCD and TDT which is in Phase 3 clinical trial. The company sells its products primarily to specialty pharmacy and specialty distributors in the United States, as well as specialty distributors and retail chains, and hospitals and clinics internationally. It has collaborations with Affinia Therapeutics, Inc.; Arbor Biotechnologies, Inc.; CRISPR Therapeutics AG.; Kymera Therapeutics, Inc.; Mammoth Biosciences, Inc.; Moderna, Inc.; Obsidian Therapeutics, Inc.; and Skyhawk Therapeutics, Inc.; as well as Ribometrix, Inc.; Genomics plc; Merck KGaA; Darmstadt, Germany, and X-Chem, Inc. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.
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Price Targets
Recent Analyst Actions
| Date | Firm | Action | Rating | Price Target |
|---|---|---|---|---|
| December 3rd 2025 | Morgan Stanley | Upgrade | Overweight | $516 |
| November 13th 2025 | Scotiabank | Initiation | Sector Outperform | $495 |
| September 25th 2025 | Leerink Partners | Upgrade | Outperform | $456 |
| September 3rd 2025 | Raymond James | Initiation | Market Perform | - |
| August 6th 2025 | Wells Fargo | Upgrade | Overweight | $460 |
| May 7th 2025 | Wolfe Research | Downgrade | Peer Perform | - |
| May 6th 2025 | Leerink Partners | Downgrade | Market Perform | $503 |
| April 22nd 2025 | Cantor Fitzgerald | Resumed | Overweight | $535 |
| February 12th 2025 | Canaccord Genuity | Upgrade | Hold | $424← $408 |
| February 11th 2025 | Canaccord Genuity | Upgrade | Hold | - |
| January 30th 2025 | Wells Fargo | Downgrade | Equal Weight | $460 |
| December 20th 2024 | H.C. Wainwright | Reiterated | Buy | $535← $600 |
| December 19th 2024 | Oppenheimer | Downgrade | Perform | - |
| December 9th 2024 | Jefferies | Upgrade | Buy | $550← $500 |
| November 14th 2024 | Citigroup | Initiation | Buy | $575 |
Earnings History & Surprises
VRTXEPS Surprise History
Quarterly EPS Details
| Period | Report Date | Estimated EPS | Actual EPS | Surprise | Result |
|---|---|---|---|---|---|
Q2 2026 | May 4, 2026 | — | — | — | — |
Q1 2026 | Feb 9, 2026 | $4.98 | — | — | — |
Q4 2025 | Nov 3, 2025 | $4.57 | $4.80 | +5.0% | ✓ BEAT |
Q3 2025 | Aug 4, 2025 | $4.29 | $4.52 | +5.4% | ✓ BEAT |
Q2 2025 | May 5, 2025 | $4.25 | $4.06 | -4.5% | ✗ MISS |
Q1 2025 | Feb 10, 2025 | $4.02 | $3.98 | -1.0% | ✗ MISS |
Q4 2024 | Nov 4, 2024 | $4.14 | $4.38 | +5.8% | ✓ BEAT |
Q3 2024 | Aug 1, 2024 | $-11.63 | $-12.83 | -10.3% | ✗ MISS |
Q2 2024 | May 6, 2024 | $4.06 | $4.76 | +17.2% | ✓ BEAT |
Q1 2024 | Feb 5, 2024 | $4.10 | $4.20 | +2.4% | ✓ BEAT |
Q4 2023 | Nov 6, 2023 | $3.97 | $4.08 | +2.8% | ✓ BEAT |
Q3 2023 | Aug 1, 2023 | $3.88 | $3.89 | +0.3% | ✓ BEAT |
Q2 2023 | May 1, 2023 | $3.00 | $3.05 | +1.7% | ✓ BEAT |
Q1 2023 | Feb 7, 2023 | $3.51 | $3.76 | +7.1% | ✓ BEAT |
Q4 2022 | Oct 27, 2022 | $3.64 | $4.01 | +10.2% | ✓ BEAT |
Q3 2022 | Aug 4, 2022 | $3.48 | $3.60 | +3.4% | ✓ BEAT |
Q2 2022 | May 5, 2022 | $3.49 | $3.52 | +0.9% | ✓ BEAT |
Q1 2022 | Jan 26, 2022 | $3.30 | $3.37 | +2.1% | ✓ BEAT |
Q4 2021 | Nov 2, 2021 | $3.08 | $3.56 | +15.6% | ✓ BEAT |
Q3 2021 | Jul 29, 2021 | $2.69 | $3.11 | +15.6% | ✓ BEAT |
Latest News
Wells Fargo Maintains Overweight on Vertex Pharmaceuticals, Raises Price Target to $515
📈 PositiveReported Saturday, Vertex Announces Pivotal CASGEVY Studies In Children Ages 5-11 Years Showing Transformative Potential And Consistent Efficacy And Safety Versus Ages 12 Years And Older
📈 PositiveCNBC Halftime Report Final Trades: Phillips 66, Nu Holdings, Vertex Pharmaceuticals, The Walt Disney Company
➖ NeutralMorgan Stanley Maintains Overweight on Vertex Pharmaceuticals, Raises Price Target to $564
📈 PositiveMorgan Stanley Upgrades Vertex Pharmaceuticals to Overweight, Raises Price Target to $516
📈 PositiveVertex CEO Says Co Has Secured 18 States For Journavx Medicaid Coverage, Goal Is All 50 States
📈 PositiveReported Saturday, Vertex 48-Week RUBY-3 Data Show 64% Proteinuria Decrease In IgA Nephropathy And 82% Decrease In Primary Membranous Nephropathy With eGFR Stabilization
📈 PositiveUBS Maintains Buy on Vertex Pharmaceuticals, Lowers Price Target to $546
📈 PositiveRBC Capital Maintains Sector Perform on Vertex Pharmaceuticals, Lowers Price Target to $415
➖ NeutralBarclays Maintains Equal-Weight on Vertex Pharmaceuticals, Raises Price Target to $414
➖ NeutralStifel Maintains Hold on Vertex Pharmaceuticals, Lowers Price Target to $445
➖ NeutralVertex Pharmaceuticals shares are trading lower. The company reported Q3 financial results.
📉 NegativeVertex Pharmaceuticals Raises FY2025 Sales Guidance from $11.850B-$12.000B to $11.900B-$12.000B vs $11.987B Est
📈 PositiveVertex Pharmaceuticals Q3 Adj. EPS $4.80 Beats $4.56 Estimate, Sales $3.076B Beat $3.053B Estimate
📈 PositiveVertex Pharmaceuticals Presents Multiple Abstracts Showing Clinical Benefits Of CFTR Modulators At North American Cystic Fibrosis Conference In Seattle
📈 PositiveReported Earlier: Vertex Advances Povetacicept Program With FDA Rolling Review For IgAN; Initiates OLYMPUS, A Phase 2b/3 Pivotal Study Of Pove For The Treatment Of pMN, And Announces Updated Date From RUBY-3 trial Accepted For Late-Breaking American Society Of Nephrology 2025 Presentation
📈 PositiveMorgan Stanley Maintains Equal-Weight on Vertex Pharmaceuticals, Lowers Price Target to $438
➖ NeutralJP Morgan Maintains Overweight on Vertex Pharmaceuticals, Raises Price Target to $530
📈 PositiveCitigroup Maintains Buy on Vertex Pharmaceuticals, Raises Price Target to $575
📈 PositiveCNBC Halftime Report Final Trades: ServiceNow; Vertex Pharmaceuticals; iShares Core S&P Small-Cap ETF
➖ NeutralFrequently Asked Questions about VRTX
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