
Sirnaomics Ltd.
2257.HKHKSEHealthcareBiotechnology
Latest quote
HK$3.78
−HK$0.085 · -2.20%
2257.HK company overview
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Company profile
Company websiteSirnaomics Ltd. is an RNA therapeutics biopharmaceutical company, founded in 2007 and headquartered in Gaithersburg, Maryland. The company is dedicated to identifying and developing innovative therapeutic compounds aimed at addressing significant medical needs across the United States and the People's Republic of China. Its leading pipeline assets include STP705, which is being investigated for conditions such as cutaneous squamous cell carcinoma in situ, basal cell carcinoma, various liver-related cancers (cholangiocarcinoma, hepatocellular carcinoma, liver metastases), as well as for keloid scar remodeling, hypertrophic scarring, and fat sculpting. Another prominent candidate, STP707, is designed to treat cholangiocarcinoma, hepatocellular carcinoma, liver metastases, metastatic cutaneous squamous cell carcinoma, non-small cell lung cancer, and both liver and lung fibrosis. Beyond these lead programs, Sirnaomics is advancing STP355 for a range of cancers; STP369 for head and neck/bladder cancers; STP779 for liver, lung, and pancreatic cancers; and STP902 for breast cancer. The company's portfolio also extends to infectious diseases with STP702 for influenza, STP908 for COVID-19, the RIM730 COVID-19 vaccine, and STP909 for HPV/cervical cancer. Furthermore, its developmental pipeline encompasses STP122G for thrombotic disorders, STP125G for hypertriglyceridemia, STP144G for complement-mediated ailments, STP133G for cardiometabolic conditions, and STP155G for hepatitis B virus.
- Industry
- Biotechnology
- Sector
- Healthcare
- Headquarters
- US
- CEO
- Hung Fai Poon
- Listed since
- Dec 30, 2021
- Employees
- 37
Market position
Day range
Current HK$3.78
52-week range
Current HK$3.78
- Open
- HK$3.865
- Previous close
- HK$3.865
- Volume
- 2.65K
- 0.03× average
- Average volume
- 101.85K
- Average daily volume
- Market cap
- 411.64M HKD
- Beta
- -0.04
- Market reference 1
- 50-day average
- HK$4.3699
- -13.50% below average
- 200-day average
- HK$6.5162
- -41.99% below average
Financials
Financial snapshot
Latest / TTMValuation & yield
- Enterprise value
- 88.87M USD
- P/E (TTM)
- -3.23×
- P/B (TTM)
- -4.61×
- P/S (TTM)
- 648.35×
- EV / EBITDA
- -6.57×
- Earnings yield
- -15.50%
- Free cash flow yield
- -9.94%
- Dividend yield
- 0.00%
Profitability & efficiency
- Gross margin
- -999.61%
- Operating margin
- -18871.00%
- Net margin
- -17806.58%
- Return on equity
- 145.51%
- Return on assets
- -70.01%
- Return on invested capital
- 101.29%
Financial health
- Debt / equity
- -0.94×
- Current ratio
- 0.4×
- Altman Z-score
- -45.14
- Piotroski F-score
- 2 of 9
Financial statements
Margin trends
Profitability as a percentage of reported revenue.
Income trends
Revenue
Operating income
Net income
| Metric (USD) | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 |
|---|---|---|---|---|---|
| Revenue | — | 1.78M USD | 397K USD | 705K USD | — |
| Cost of goods sold | 1.84M USD | 579K USD | — | — | 12.67M USD |
| Gross profit | −1.84M USD | 1.2M USD | 397K USD | 705K USD | −12.67M USD |
| Research and development | 8.99M USD | 20.8M USD | 54.38M USD | 67.64M USD | 306.02M USD |
| Selling, general, and administrative | 4.54M USD | 17.16M USD | 23.16M USD | 15.72M USD | 122.76M USD |
| Operating expenses | 13.53M USD | 37.96M USD | 77.54M USD | 91.83M USD | 428.77M USD |
| Interest income | 29.04K USD | 56K USD | 27K USD | 1.35M USD | 1.66M USD |
| Interest expense | 813.2K USD | 1.05M USD | 986K USD | 798K USD | 2.63M USD |
| Depreciation and amortization | 1.84M USD | 4.67M USD | 4.78M USD | 2.11M USD | 12.67M USD |
| Operating income | −15.37M USD | −36.76M USD | −77.15M USD | −91.13M USD | −441.44M USD |
| Net income | −14.42M USD | −51.38M USD | −78.69M USD | −88.3M USD | −1.66B USD |
Company facts updated Aug 24, 2026.
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