Hua Medicine (Shanghai) Ltd. logo

Hua Medicine (Shanghai) Ltd.

2552.HK

HKSEHealthcareDrug Manufacturers - Specialty & Generic

Latest quote

HK$2.56

−HK$0.04 · -1.54%

Aug 24, 4:08 PM HKT

2552.HK company overview

Regular session · HKT · Market data may be delayed.

Company profile

Company website

Hua Medicine (Shanghai) Ltd., a biopharmaceutical enterprise established in 2011 and headquartered in Beijing, China, specializes in the clinical development of novel therapeutic solutions, with a primary focus on addressing diabetes within the Chinese market. Its lead asset, Dorzagliatin (also known as HMS5552), is an orally administered medication designed for Type 2 Diabetes. The company is also advancing various combination therapies involving Dorzagliatin for T2D, including pairings with Metformin, Sitagliptin, and Empagliflozin, all of which are currently undergoing Phase I clinical trials. Furthermore, Hua Medicine explores the potential of Dorzagliatin in combination with Pioglitazone for Non-alcoholic steatohepatitis (NASH), with GLP-1 for Alzheimer's disease, and for applications in late-stage Type 2 Diabetes and Type 1 Diabetes. Beyond its diabetes pipeline, the company is developing mGLUR5 as a potential treatment for levodopa-induced dyskinesia in Parkinson's disease patients.

Industry
Drug Manufacturers - Specialty & Generic
Sector
Healthcare
Headquarters
CN
CEO
Li Chen
Listed since
Sep 14, 2018
Employees
328

Market position

Day range

Current HK$2.56

52-week range

Current HK$2.56

Open
HK$2.60
Previous close
HK$2.60
Volume
2.37M
0.84× average
Average volume
2.81M
Average daily volume
Market cap
2.55B HKD
Beta
0.8
Market reference 1
50-day average
HK$2.4353
+5.12% above average
200-day average
HK$3.0114
-14.99% below average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
1.94B CNY
P/E (TTM)
-21.52×
P/B (TTM)
2.21×
P/S (TTM)
3.39×
EV / EBITDA
-17.74×
Earnings yield
39.43%
Free cash flow yield
-2.18%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
60.64%
Operating margin
-16.23%
Net margin
-16.46%
Return on equity
107.04%
Return on assets
73.30%
Return on invested capital
-10.78%

Financial health

Debt / equity
0.36×
Current ratio
6.17×
Altman Z-score
3.24
Piotroski F-score
5 of 9

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends399%-298%-995%-1692%Gross margin, FY2022: 43.69%Gross margin, FY2023: 48.78%Gross margin, FY2024: 48.74%Gross margin, FY2025: 56.87%Operating margin, FY2022: -1517.80%Operating margin, FY2023: -377.36%Operating margin, FY2024: -137.81%Operating margin, FY2025: -29.39%Net margin, FY2022: -1157.83%Net margin, FY2023: -275.73%Net margin, FY2024: -97.75%Net margin, FY2025: 224.44%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2022 43.69%. Gross margin FY2023 48.78%. Gross margin FY2024 48.74%. Gross margin FY2025 56.87%. Operating margin FY2022 -1517.80%. Operating margin FY2023 -377.36%. Operating margin FY2024 -137.81%. Operating margin FY2025 -29.39%. Net margin FY2022 -1157.83%. Net margin FY2023 -275.73%. Net margin FY2024 -97.75%. Net margin FY2025 224.44%.

Income trends

Revenue

480.18M CNY+87.65%

Operating income

−141.13M CNY+59.98%

Net income

1.08B CNY+1.33B CNY
Income trends across reported periods1.22B CNY648.61M CNY76.47M CNY−495.68M CNYRevenue, FY2022: 17.6M CNYRevenue, FY2023: 76.61M CNYRevenue, FY2024: 255.89M CNYRevenue, FY2025: 480.18M CNYOperating income, FY2021: −320.52M CNYOperating income, FY2022: −267.12M CNYOperating income, FY2023: −289.09M CNYOperating income, FY2024: −352.64M CNYOperating income, FY2025: −141.13M CNYNet income, FY2021: −330.95M CNYNet income, FY2022: −203.77M CNYNet income, FY2023: −211.23M CNYNet income, FY2024: −250.14M CNYNet income, FY2025: 1.08B CNYFY2021FY2022FY2023FY2024FY2025
Revenue FY2022 17.6M CNY. Revenue FY2023 76.61M CNY. Revenue FY2024 255.89M CNY. Revenue FY2025 480.18M CNY. Operating income FY2021 −320.52M CNY. Operating income FY2022 −267.12M CNY. Operating income FY2023 −289.09M CNY. Operating income FY2024 −352.64M CNY. Operating income FY2025 −141.13M CNY. Net income FY2021 −330.95M CNY. Net income FY2022 −203.77M CNY. Net income FY2023 −211.23M CNY. Net income FY2024 −250.14M CNY. Net income FY2025 1.08B CNY.
Metric (CNY)FY2025FY2024FY2023FY2022FY2021
Revenue480.18M CNY255.89M CNY76.61M CNY17.6M CNY
Cost of goods sold207.08M CNY131.17M CNY39.24M CNY9.91M CNY38.48M CNY
Gross profit273.1M CNY124.72M CNY37.37M CNY7.69M CNY−38.48M CNY
Research and development141.56M CNY215.09M CNY171.54M CNY129.53M CNY186.84M CNY
Selling, general, and administrative279.92M CNY269.94M CNY203.9M CNY145.28M CNY134.84M CNY
Operating expenses414.23M CNY477.37M CNY375.44M CNY274.81M CNY321.67M CNY
Interest income11.19M CNY13.44M CNY16.51M CNY4.24M CNY5.04M CNY
Interest expense7.94M CNY8.61M CNY7.91M CNY3.67M CNY3.95M CNY
Depreciation and amortization31.63M CNY14.94M CNY36.24M CNY31.78M CNY11.98M CNY
Operating income−141.13M CNY−352.64M CNY−289.09M CNY−267.12M CNY−320.52M CNY
Net income1.08B CNY−250.14M CNY−211.23M CNY−203.77M CNY−330.95M CNY

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
67%
6 beats, 3 misses, 0 met estimates
Average EPS surprise
+40.84%
9 comparable reports
Latest EPS result
-0.03
Estimate -0.22 · Beat by 83.79%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates1.430.810.19-0.42Q3 '23MissQ1 '24MissQ3 '24No estimateQ1 '25BeatQ3 '25BeatQ1 '26No estimateQ3 '26BeatQ2 '27Estimate
Q3 2023, reported Aug 24, 2023: actual -0.097, estimate 0.377, surprise -125.72%, Miss. Q1 2024, reported Mar 28, 2024: actual -0.137, estimate 0.581, surprise -123.55%, Miss. Q3 2024, reported Aug 29, 2024: actual -0.165, estimate —, surprise —, Comparison unavailable. Q1 2025, reported Mar 27, 2025: actual -0.117, estimate -0.296, surprise +60.51%, Beat. Q3 2025, reported Aug 28, 2025: actual 1.3, estimate -0.296, surprise +539.13%, Beat. Q1 2026, reported Mar 26, 2026: actual -0.08, estimate —, surprise —, Comparison unavailable. Q3 2026, reported Aug 20, 2026: actual -0.035, estimate -0.216, surprise +83.79%, Beat. Q2 2027, reported Apr 1, 2027: actual —, estimate 0.581, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates929.02M621.32M313.61M5.91MQ3 '23MissQ1 '24MissQ3 '24MissQ1 '25MissQ3 '25MissQ1 '26No estimateQ3 '26MissQ2 '27Estimate
Q3 2023, reported Aug 24, 2023: actual 75.69M HKD, estimate 631.09M HKD, surprise -88.01%, Miss. Q1 2024, reported Mar 28, 2024: actual 6.95M HKD, estimate 860.72M HKD, surprise -99.19%, Miss. Q3 2024, reported Aug 29, 2024: actual 112.98M HKD, estimate 583.68M HKD, surprise -80.64%, Miss. Q1 2025, reported Mar 27, 2025: actual 163.01M HKD, estimate 237.89M HKD, surprise -31.48%, Miss. Q3 2025, reported Aug 28, 2025: actual 237.65M HKD, estimate 251.26M HKD, surprise -5.42%, Miss. Q1 2026, reported Mar 26, 2026: actual 301.38M HKD, estimate —, surprise —, Comparison unavailable. Q3 2026, reported Aug 20, 2026: actual 441.83M HKD, estimate 575.09M HKD, surprise -23.17%, Miss. Q2 2027, reported Apr 1, 2027: actual —, estimate 860.02M HKD, surprise —, Comparison unavailable.

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