Shanghai Henlius Biotech, Inc. logo

Shanghai Henlius Biotech, Inc.

2696.HK

HKSEHealthcareBiotechnology

Latest quote

HK$66.15

−HK$2.45 · -3.57%

Aug 24, 2:05 PM HKT

2696.HK company overview

Regular session · HKT · Market data may be delayed.

Company profile

Company website

Shanghai Henlius Biotech, Inc. functions as a biopharmaceutical enterprise, dedicated to the research and advancement of biologic medicines, with a primary focus on cancer, autoimmune conditions, and ophthalmic disorders. Its commercial portfolio encompasses several approved biologic treatments. Specifically, it markets HANLIKANG, a rituximab injection utilized for non-Hodgkin lymphoma, chronic lymphocytic leukemia, and rheumatoid arthritis; HANQUYOU, a trastuzumab injection indicated for breast and metastatic gastric cancer; HANDAYUAN, an adalimumab injection for rheumatoid arthritis, ankylosing spondylitis, plaque psoriasis, and uveitis; HANBEITAI, a bevacizumab injection with indications in metastatic colorectal cancer (mCRC) and non-squamous non-small cell lung cancer (nsNSCLC); and HANSIZHUANG, a serplulimab injection for microsatellite instability-high solid tumors. In addition to its marketed products, Shanghai Henlius is actively progressing its robust development pipeline, which includes Serplulimab, undergoing further development for applications such as squamous non-small cell lung cancer (sqNSCLC), extensive small-cell lung cancer, metastatic esophageal squamous-cell carcinomas, neo-/adjuvant treatment of gastric cancer, hepatocellular carcinoma, mCRC, nsNSCLC, squamous cell carcinoma of the head and neck (SCCHN), and a range of other solid tumor types. Among its other investigational compounds are HLX04-O, a bevacizumab injection aimed at wet age-related macular degeneration; HLX22 for breast and metastatic gastric cancer; a group of therapies—HLX07, HLX23, HLX35, HLX208, HLX55, HLX301, and HLX20—collectively aimed at solid tumors; HLX11 for breast cancer; HLX05, a cetuximab injection for mCRC and SCCHN; HLX12, addressing gastric cancer, metastatic non-small cell lung cancer, and mCRC; and HLX14, designed to treat osteoporosis. Further expanding its pipeline, HLX26 is being developed for solid tumors and lymphoma; HLX13 is under investigation for melanoma, renal cell carcinoma, and mCRC; HLX15 for multiple myeloma; and HLX71, with potential for treating COVID-19. The firm conducts its operations across Mainland China, Europe, the broader Asia-Pacific region, and various other international territories. Founded in 2010, its headquarters are situated in Shanghai, China. Shanghai Henlius Biotech, Inc. operates as a subsidiary of Shanghai Fosun Pharmaceutical (Group) Co., Ltd.

Industry
Biotechnology
Sector
Healthcare
Headquarters
CN
CEO
Jun Zhu
Listed since
Sep 25, 2019
Employees
3,762

Market position

Day range

Current HK$66.15

52-week range

Current HK$66.15

Open
HK$69.05
Previous close
HK$68.60
Volume
579.24K
0.7× average
Average volume
827.73K
Average daily volume
Market cap
35.95B HKD
Beta
0.5
Market reference 1
50-day average
HK$62.269
+6.23% above average
200-day average
HK$66.2478
-0.15% below average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
30.89B CNY
EV / EBITDA
26.56×
Earnings yield
2.87%
Free cash flow yield
3.06%

Profitability & efficiency

Return on equity
20.33%
Return on assets
6.51%
Return on invested capital
8.45%

Financial health

Current ratio
0.71×
Altman Z-score
2.6
Piotroski F-score
5 of 9

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends88%35%-19%-72%Gross margin, FY2021: 68.93%Gross margin, FY2022: 73.73%Gross margin, FY2023: 72.64%Gross margin, FY2024: 73.10%Gross margin, FY2025: 74.77%Operating margin, FY2021: -39.54%Operating margin, FY2022: -19.55%Operating margin, FY2023: 11.71%Operating margin, FY2024: 16.41%Operating margin, FY2025: 12.26%Net margin, FY2021: -58.49%Net margin, FY2022: -21.63%Net margin, FY2023: 10.12%Net margin, FY2024: 14.33%Net margin, FY2025: 12.08%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2021 68.93%. Gross margin FY2022 73.73%. Gross margin FY2023 72.64%. Gross margin FY2024 73.10%. Gross margin FY2025 74.77%. Operating margin FY2021 -39.54%. Operating margin FY2022 -19.55%. Operating margin FY2023 11.71%. Operating margin FY2024 16.41%. Operating margin FY2025 12.26%. Net margin FY2021 -58.49%. Net margin FY2022 -21.63%. Net margin FY2023 10.12%. Net margin FY2024 14.33%. Net margin FY2025 12.08%.

Income trends

Revenue

6.67B CNY+16.46%

Operating income

817.12M CNY-12.99%

Net income

805.64M CNY-1.81%
Income trends across reported periods7.43B CNY4.37B CNY1.31B CNY−1.75B CNYRevenue, FY2021: 1.68B CNYRevenue, FY2022: 3.21B CNYRevenue, FY2023: 5.39B CNYRevenue, FY2024: 5.72B CNYRevenue, FY2025: 6.67B CNYOperating income, FY2021: −665.25M CNYOperating income, FY2022: −628.53M CNYOperating income, FY2023: 631.7M CNYOperating income, FY2024: 939.13M CNYOperating income, FY2025: 817.12M CNYNet income, FY2021: −984.05M CNYNet income, FY2022: −695.26M CNYNet income, FY2023: 546.02M CNYNet income, FY2024: 820.47M CNYNet income, FY2025: 805.64M CNYFY2021FY2022FY2023FY2024FY2025
Revenue FY2021 1.68B CNY. Revenue FY2022 3.21B CNY. Revenue FY2023 5.39B CNY. Revenue FY2024 5.72B CNY. Revenue FY2025 6.67B CNY. Operating income FY2021 −665.25M CNY. Operating income FY2022 −628.53M CNY. Operating income FY2023 631.7M CNY. Operating income FY2024 939.13M CNY. Operating income FY2025 817.12M CNY. Net income FY2021 −984.05M CNY. Net income FY2022 −695.26M CNY. Net income FY2023 546.02M CNY. Net income FY2024 820.47M CNY. Net income FY2025 805.64M CNY.
Metric (CNY)FY2025FY2024FY2023FY2022FY2021
Revenue6.67B CNY5.72B CNY5.39B CNY3.21B CNY1.68B CNY
Cost of goods sold1.68B CNY1.54B CNY1.48B CNY844.62M CNY522.75M CNY
Gross profit4.98B CNY4.18B CNY3.92B CNY2.37B CNY1.16B CNY
Research and development1.52B CNY1.04B CNY1.12B CNY1.39B CNY1.02B CNY
Selling, general, and administrative2.65B CNY2.29B CNY2.14B CNY1.4B CNY800.87M CNY
Operating expenses4.17B CNY3.25B CNY3.29B CNY3B CNY1.82B CNY
Interest income18.3M CNY21.7M CNY8.15M CNY3.57M CNY2.69M CNY
Interest expense99.84M CNY122.89M CNY110.54M CNY105.67M CNY84.82M CNY
Depreciation and amortization346.05M CNY279.63M CNY279.63M CNY277.6M CNY200.18M CNY
Operating income817.12M CNY939.13M CNY631.7M CNY−628.53M CNY−665.25M CNY
Net income805.64M CNY820.47M CNY546.02M CNY−695.26M CNY−984.05M CNY

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
100%
2 beats, 0 misses, 0 met estimates
Average EPS surprise
+64.59%
2 comparable reports
Latest EPS result
0.91
Estimate 0.5 · Beat by 83.76%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates6.354.342.340.33Q4 '24No estimateQ4 '24No estimateQ1 '25No estimateQ3 '25No estimateQ1 '26BeatQ1 '26EstimateQ3 '26BeatQ1 '27Estimate
Q4 2024, reported Nov 18, 2024: actual 0.443, estimate —, surprise —, Comparison unavailable. Q4 2024, reported Dec 31, 2024: actual 0.425, estimate —, surprise —, Comparison unavailable. Q1 2025, reported Mar 24, 2025: actual 0.384, estimate —, surprise —, Comparison unavailable. Q3 2025, reported Aug 25, 2025: actual 0.783, estimate —, surprise —, Comparison unavailable. Q1 2026, reported Mar 20, 2026: actual 0.89, estimate 0.612, surprise +45.42%, Beat. Q1 2026, reported Mar 24, 2026: actual —, estimate 0.612, surprise —, Comparison unavailable. Q3 2026, reported Aug 21, 2026: actual 0.912, estimate 0.496, surprise +83.76%, Beat. Q1 2027, reported Mar 19, 2027: actual —, estimate 5.91, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates8.49B6.09B3.68B1.28BQ4 '24No estimateQ4 '24No estimateQ1 '25No estimateQ3 '25BeatQ1 '26BeatQ1 '26EstimateQ3 '26BeatQ1 '27Estimate
Q4 2024, reported Nov 18, 2024: actual 1.65B HKD, estimate —, surprise —, Comparison unavailable. Q4 2024, reported Dec 31, 2024: actual 1.58B HKD, estimate —, surprise —, Comparison unavailable. Q1 2025, reported Mar 24, 2025: actual 1.5B HKD, estimate —, surprise —, Comparison unavailable. Q3 2025, reported Aug 25, 2025: actual 3.07B HKD, estimate 1.54B HKD, surprise +98.86%, Beat. Q1 2026, reported Mar 20, 2026: actual 4.28B HKD, estimate 3.48B HKD, surprise +22.88%, Beat. Q1 2026, reported Mar 24, 2026: actual —, estimate 3.48B HKD, surprise —, Comparison unavailable. Q3 2026, reported Aug 21, 2026: actual 4.14B HKD, estimate 3.93B HKD, surprise +5.30%, Beat. Q1 2027, reported Mar 19, 2027: actual —, estimate 7.97B HKD, surprise —, Comparison unavailable.

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