Amylyx Pharmaceuticals, Inc. logo

Amylyx Pharmaceuticals, Inc.

AMLX

NASDAQHealthcareBiotechnology

Previous close

$38.66

−$1.00 · -2.52%

Aug 21, 4:00 PM ET

AMLX company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Hold

Wait — insufficient conviction to act

Valuation

25

Expensive

Momentum

65

Gaining

Sentiment

73

Bullish

Risk resilience

64

Moderate Risk

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Company profile

Company website

Amylyx Pharmaceuticals, Inc. operates as a clinical-stage biopharmaceutical firm, primarily focused on creating therapies for amyotrophic lateral sclerosis (ALS) and various other neurodegenerative conditions. A key asset in its developmental pipeline is AMX0035, a proprietary dual UPR-Bax apoptosis inhibitor. This compound, which integrates sodium phenylbutyrate and taurursodiol, is under investigation for treating ALS, and its application is also being explored for other neurodegenerative diseases. The company was established in 2013 and is based in Cambridge, Massachusetts.

Industry
Biotechnology
Sector
Healthcare
Headquarters
US
CEO
Joshua Cohen
Listed since
Jan 7, 2022
Employees
136

Market position

Day range

Current $38.66

52-week range

Current $38.66

Open
$39.73
Previous close
$39.66
Volume
4.64M
2.37× average
Average volume
1.96M
Average daily volume
Market cap
4.3B USD
Beta
-0.21
Market reference 1
50-day average
$20.267
+90.75% above average
200-day average
$15.7351
+145.69% above average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
921.66M USD
P/E (TTM)
-27.42×
P/B (TTM)
17.97×
P/S (TTM)
EV / EBITDA
-6.39×
Earnings yield
-12.67%
Free cash flow yield
-10.81%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
0.00%
Operating margin
0.00%
Net margin
0.00%
Return on equity
-47.41%
Return on assets
-43.51%
Return on invested capital
-49.26%

Financial health

Debt / equity
0.02×
Current ratio
14.27×

Earnings

EPS beat rate
27%
3 beats, 8 misses, 0 met estimates
Average EPS surprise
-1059.08%
11 comparable reports
Latest EPS result
-0.39
Estimate -0.36 · Miss by 8.06%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates-0.26-0.37-0.48-0.59Q1 '25MissQ2 '25BeatQ3 '25MissQ4 '25BeatQ1 '26BeatQ2 '26MissQ3 '26MissQ4 '26Estimate
Q1 2025, reported Mar 4, 2025: actual -0.55, estimate -0.49, surprise -12.24%, Miss. Q2 2025, reported May 8, 2025: actual -0.42, estimate -0.45, surprise +6.67%, Beat. Q3 2025, reported Aug 7, 2025: actual -0.46, estimate -0.44, surprise -4.55%, Miss. Q4 2025, reported Nov 6, 2025: actual -0.37, estimate -0.43, surprise +13.95%, Beat. Q1 2026, reported Mar 3, 2026: actual -0.3, estimate -0.31, surprise +3.23%, Beat. Q2 2026, reported May 7, 2026: actual -0.37, estimate -0.34, surprise -8.82%, Miss. Q3 2026, reported Aug 6, 2026: actual -0.39, estimate -0.361, surprise -8.06%, Miss. Q4 2026, reported Nov 5, 2026: actual —, estimate -0.38, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates117.13M75.18M33.22M-8.73MQ1 '24BeatQ2 '24MissQ3 '24MissQ4 '24MissQ1 '25No estimateQ4 '25EstimateQ1 '26EstimateQ4 '26Estimate
Q1 2024, reported Feb 22, 2024: actual 108.45M USD, estimate 106.96M USD, surprise +1.39%, Beat. Q2 2024, reported May 10, 2024: actual 88.6M USD, estimate 98.35M USD, surprise -9.91%, Miss. Q3 2024, reported Aug 8, 2024: actual 1.02M USD, estimate 10.66M USD, surprise -90.41%, Miss. Q4 2024, reported Nov 7, 2024: actual 416K USD, estimate 31.57M USD, surprise -98.68%, Miss. Q1 2025, reported Mar 4, 2025: actual 665K USD, estimate —, surprise —, Comparison unavailable. Q4 2025, reported Nov 6, 2025: actual —, estimate 52K USD, surprise —, Comparison unavailable. Q1 2026, reported Mar 3, 2026: actual —, estimate -52K USD, surprise —, Comparison unavailable. Q4 2026, reported Nov 5, 2026: actual —, estimate 59.43K USD, surprise —, Comparison unavailable.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Rating distribution

11 ratings
Strong buy00%
Buy1091%
Hold19%
Sell00%
Strong sell00%

AMLX news

Corporate actions

Corporate action history

Dividend

Ex-dividend Mar 28, 2018

$0.42

Quarterly

Payment Apr 2, 2018

Dividend

Ex-dividend Dec 28, 2017

$0.36

Quarterly

Payment Jan 2, 2018

Dividend

Ex-dividend Sep 28, 2017

$0.24

Quarterly

Payment Oct 2, 2017

AMLX peers

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