AnaptysBio, Inc. logo

AnaptysBio, Inc.

ANAB

NASDAQHealthcareBiotechnology

Previous close

$57.74

+$1.05 · +1.85%

Aug 21, 4:00 PM ET

ANAB company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Buy

Favorable setup — positive multi-factor alignment

Valuation

76

Undervalued

Momentum

67

Gaining

Sentiment

60

Mixed

Risk resilience

64

Moderate Risk

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Company profile

Company website

AnaptysBio, Inc., a clinical-stage biotechnology company, focuses in delivering immunology therapeutics for autoimmune and inflammatory diseases in the United States. The company’s products include Rosnilimab, a selective pathogenic T cell deplete which completed a Phase 2b trial for the treatment of moderate-to-severe rheumatoid arthritis; ANB033, a CD122 antagonist, which is in a Phase 1b trial for celiac disease and eosinophilic esophagitis; ANB101, a BDCA2 modulator antibody which is in Phase 1a trial that specifically targets plasmacytoid dendritic cells and inhibits interferon secretion and modulates antigen presentation; dostarlimab, a PD-1 antagonist for various solid tumor indications; and Imsidolimab, an antibody that inhibits the interleukin-36 receptor, which is in the Phase 3 development for the treatment of generalized pustular psoriasis. It focuses on developing various antibody programs that are advanced to preclinical and clinical milestones under its collaborations. It has collaborations agreement with GSK and Vanda. The company was formerly known as Anaptys Biosciences, Inc. and changed its name to AnaptysBio, Inc. in July 2006. AnaptysBio, Inc. was incorporated in 2005 and is based in San Diego, California.

Industry
Biotechnology
Sector
Healthcare
Headquarters
US
CEO
Daniel Faga
Listed since
Jan 26, 2017
Employees
104

Market position

Day range

Current $57.74

52-week range

Current $57.74

Open
$56.62
Previous close
$56.69
Volume
318.37K
0.5× average
Average volume
642.6K
Average daily volume
Market cap
1.71B USD
Beta
0.4
Market reference 1
50-day average
$58.3467
-1.04% below average
200-day average
$44.758
+29.00% above average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
674.06M USD
P/E (TTM)
-66.37×
P/B (TTM)
129.96×
P/S (TTM)
7.36×
EV / EBITDA
9.73×
Earnings yield
-1.47%
Free cash flow yield
2.18%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
116.42%
Operating margin
17.56%
Net margin
-11.53%
Return on equity
-35.56%
Return on assets
-3.63%
Return on invested capital
14.61%

Financial health

Debt / equity
21.76×
Current ratio
9.07×

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends234%-306%-846%-1386%Gross margin, FY2021: -55.91%Gross margin, FY2022: -763.21%Gross margin, FY2023: -671.01%Gross margin, FY2024: -79.49%Gross margin, FY2025: 98.97%Operating margin, FY2021: -89.93%Operating margin, FY2022: -1119.41%Operating margin, FY2023: -958.27%Operating margin, FY2024: -125.93%Operating margin, FY2025: 20.42%Net margin, FY2021: -91.49%Net margin, FY2022: -1251.33%Net margin, FY2023: -953.66%Net margin, FY2024: -159.10%Net margin, FY2025: -5.64%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2021 -55.91%. Gross margin FY2022 -763.21%. Gross margin FY2023 -671.01%. Gross margin FY2024 -79.49%. Gross margin FY2025 98.97%. Operating margin FY2021 -89.93%. Operating margin FY2022 -1119.41%. Operating margin FY2023 -958.27%. Operating margin FY2024 -125.93%. Operating margin FY2025 20.42%. Net margin FY2021 -91.49%. Net margin FY2022 -1251.33%. Net margin FY2023 -953.66%. Net margin FY2024 -159.10%. Net margin FY2025 -5.64%.

Income trends

Revenue

234.6M USD+157.01%

Operating income

47.9M USD+162.85M USD

Net income

−13.23M USD+90.89%
Income trends across reported periods274.5M USD114.9M USD−44.71M USD−204.31M USDRevenue, FY2021: 63.18M USDRevenue, FY2022: 10.29M USDRevenue, FY2023: 17.16M USDRevenue, FY2024: 91.28M USDRevenue, FY2025: 234.6M USDOperating income, FY2021: −56.81M USDOperating income, FY2022: −115.15M USDOperating income, FY2023: −164.41M USDOperating income, FY2024: −114.95M USDOperating income, FY2025: 47.9M USDNet income, FY2021: −57.8M USDNet income, FY2022: −128.72M USDNet income, FY2023: −163.62M USDNet income, FY2024: −145.23M USDNet income, FY2025: −13.23M USDFY2021FY2022FY2023FY2024FY2025
Revenue FY2021 63.18M USD. Revenue FY2022 10.29M USD. Revenue FY2023 17.16M USD. Revenue FY2024 91.28M USD. Revenue FY2025 234.6M USD. Operating income FY2021 −56.81M USD. Operating income FY2022 −115.15M USD. Operating income FY2023 −164.41M USD. Operating income FY2024 −114.95M USD. Operating income FY2025 47.9M USD. Net income FY2021 −57.8M USD. Net income FY2022 −128.72M USD. Net income FY2023 −163.62M USD. Net income FY2024 −145.23M USD. Net income FY2025 −13.23M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Revenue234.6M USD91.28M USD17.16M USD10.29M USD63.18M USD
Cost of goods sold2.42M USD163.84M USD132.28M USD88.8M USD98.5M USD
Gross profit232.18M USD−72.56M USD−115.13M USD−78.51M USD−35.32M USD
Research and development135.97M USD163.84M USD139.62M USD88.8M USD98.5M USD
Selling, general, and administrative50.74M USD42.39M USD41.95M USD36.64M USD21.49M USD
Operating expenses184.28M USD42.39M USD49.29M USD36.64M USD21.49M USD
Interest income13.5M USD19.79M USD18.87M USD7.55M USD431K USD
Interest expense79.89M USD50.09M USD18.08M USD21.11M USD1.45M USD
Depreciation and amortization2.42M USD2.4M USD652K USD2.34M USD2.09M USD
Operating income47.9M USD−114.95M USD−164.41M USD−115.15M USD−56.81M USD
Net income−13.23M USD−145.23M USD−163.62M USD−128.72M USD−57.8M USD

Company facts updated Aug 24, 2026.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Analyst price target

Average target

$73.67

27.59% upside
Past 12 months12-month forecastHigh $90.00Average $73.67Low $50.00

Recent analyst actions

12 institutions
Leerink PartnersmaintainOutperform

ANAB news

ANAB peers

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