
Alto Neuroscience, Inc.
ANRONYSEHealthcareBiotechnology
Previous close
$34.28
+$0.03 · +0.09%
ANRO company overview
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GoAI snapshot
AI-powered factor overview
GoAI score
Hold
Wait — insufficient conviction to act
Valuation
40
Expensive
Momentum
79
Gaining
Sentiment
61
Bullish
Risk resilience
55
Elevated Risk
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Company profile
Company websiteAlto Neuroscience, Inc. operates as a biopharmaceutical entity in the clinical stage, specializing in the creation of novel psychiatric medications. Its development pipeline includes ALTO-100, an investigational therapy targeting individuals affected by major depressive disorder (MDD) and post-traumatic stress disorder. Also in its portfolio is ALTO-300, a small molecule designed to function as both a melatonergic agonist and serotonergic antagonist, exhibiting antidepressant properties for MDD patients. For addressing the cognitive impairments linked with schizophrenia, Alto Neuroscience is advancing ALTO-101, an innovative small molecule phosphodiesterase 4 inhibitor. The company's therapeutic candidates further extend to ALTO-203, a pioneering small-molecule histamine H3 receptor inverse agonist intended for MDD patients experiencing heightened anhedonia, and ALTO-202, an orally available antagonist of the GluN2B subunit of the NMDA receptor, also under investigation for MDD. Beyond these individual drug candidates, the firm is engaged in developing novel drug combinations that demonstrate synergistic pharmacodynamic effects. Crucially, Alto Neuroscience leverages an advanced AI-enabled biomarker platform that synthesizes data concerning patients' brain activity and behavioral patterns. This platform's purpose is to accurately identify which individuals are most likely to respond positively to its cutting-edge product candidates. Alto Neuroscience, Inc., established in 2019, maintains its headquarters in Los Altos, California.
- Industry
- Biotechnology
- Sector
- Healthcare
- Headquarters
- US
- CEO
- Amit Etkin
- Listed since
- Feb 2, 2024
- Employees
- 68
Market position
Day range
Current $34.28
52-week range
Current $34.28
- Open
- $34.44
- Previous close
- $34.25
- Volume
- 238.71K
- 0.52× average
- Average volume
- 459.2K
- Average daily volume
- Market cap
- 1.2B USD
- Beta
- 1.09
- Market reference 1
- 50-day average
- $27.262
- +25.74% above average
- 200-day average
- $21.0723
- +62.68% above average
Financials
Financial snapshot
Latest / TTMValuation & yield
- P/E (TTM)
- -13.82×
- P/B (TTM)
- 6.69×
- P/S (TTM)
- 0×
- Dividend yield
- 0.00%
Profitability & efficiency
- Gross margin
- 0.00%
- Operating margin
- 0.00%
- Net margin
- 0.00%
Financial health
- Debt / equity
- 0.03×
- Altman Z-score
- 19.35
- Piotroski F-score
- 2 of 9
Financial statements
Income trends
Operating income
Net income
| Metric (USD) | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 |
|---|---|---|---|---|---|
| Revenue | — | — | — | — | 210K USD |
| Cost of goods sold | 661K USD | 502K USD | — | 342K USD | 145K USD |
| Gross profit | −661K USD | −502K USD | — | −342K USD | 65K USD |
| Research and development | 45.62M USD | 47M USD | 30.29M USD | 23.69M USD | 8.37M USD |
| Selling, general, and administrative | 20.75M USD | 21.61M USD | 7.52M USD | 5.16M USD | 3.75M USD |
| Operating expenses | 65.7M USD | 68.11M USD | 37.81M USD | 28.85M USD | 12.12M USD |
| Interest income | 6.6M USD | 8.85M USD | 2.35M USD | 114K USD | 2K USD |
| Interest expense | 2.47M USD | −1.38M USD | 1.37M USD | — | — |
| Depreciation and amortization | 661K USD | 502K USD | 373K USD | 342K USD | 145K USD |
| Operating income | −66.36M USD | −68.61M USD | −37.81M USD | −29.19M USD | −12.06M USD |
| Net income | −63.24M USD | −61.43M USD | −36.31M USD | −27.71M USD | −9.19M USD |
Company facts updated Aug 24, 2026.
Earnings
- EPS beat rate
- 64%
- 7 beats, 4 misses, 0 met estimates
- Average EPS surprise
- -35.28%
- 11 comparable reports
- Latest EPS result
- -0.65
- Estimate -0.73 · Beat by 11.51%
EPS: actual versus estimate
Recent quarterly results
Analyst ratings
Third-party consensus; not a GoAI recommendation.
Analyst price target
Average target
$37.40
9.10% upsidePrice history unavailable
High $55.00Average $37.40Low $24.00Recent analyst actions
ANRO peers
ETFs holding ANRO
Funds reporting this stock among their holdings, ordered by reported position size.
Vanguard Morningstar Total Stock Market ETFVTI27.39M0.00%2.3T USD0.03%$378.24—
iShares Russell 2000 ETFIWM22.67M0.03%81.62B USD0.19%$299.96—
Vanguard Extended Market ETFVXF9.4M0.01%93.7B USD0.05%$245.53—
iShares Biotechnology ETFIBB9.01M0.09%10.75B USD0.44%$213.56—
iShares Russell 2000 Growth ETFIWO8.23M0.05%15.16B USD0.24%$387.37—
State Street SPDR S&P Pharmaceuticals ETFXPH7.95M1.42%——$72.80—
Vanguard Russell 2000 ETFVTWO3.97M0.02%17.4B USD0.06%$121.25—
iShares Micro-Cap ETFIWC3.09M0.20%1.53B USD0.60%$198.39—
Vanguard Morningstar Total Stock Market ETFVTI- Market value
- 27.39M
- Weight
- 0.00%
- AUM
- 2.3T USD
- Expense ratio
- 0.03%
- Price / 1D
- $378.24—
iShares Russell 2000 ETFIWM- Market value
- 22.67M
- Weight
- 0.03%
- AUM
- 81.62B USD
- Expense ratio
- 0.19%
- Price / 1D
- $299.96—
Vanguard Extended Market ETFVXF- Market value
- 9.4M
- Weight
- 0.01%
- AUM
- 93.7B USD
- Expense ratio
- 0.05%
- Price / 1D
- $245.53—
iShares Biotechnology ETFIBB- Market value
- 9.01M
- Weight
- 0.09%
- AUM
- 10.75B USD
- Expense ratio
- 0.44%
- Price / 1D
- $213.56—
iShares Russell 2000 Growth ETFIWO- Market value
- 8.23M
- Weight
- 0.05%
- AUM
- 15.16B USD
- Expense ratio
- 0.24%
- Price / 1D
- $387.37—
State Street SPDR S&P Pharmaceuticals ETFXPH- Market value
- 7.95M
- Weight
- 1.42%
- AUM
- —
- Expense ratio
- —
- Price / 1D
- $72.80—
Vanguard Russell 2000 ETFVTWO- Market value
- 3.97M
- Weight
- 0.02%
- AUM
- 17.4B USD
- Expense ratio
- 0.06%
- Price / 1D
- $121.25—
iShares Micro-Cap ETFIWC- Market value
- 3.09M
- Weight
- 0.20%
- AUM
- 1.53B USD
- Expense ratio
- 0.60%
- Price / 1D
- $198.39—
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