aTyr Pharma, Inc. logo

aTyr Pharma, Inc.

ATYR

NASDAQHealthcareBiotechnology

Previous close

$0.5015

−$0.0015 · -0.30%

Aug 21, 4:00 PM ET

ATYR company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Strong Sell

Exit — multiple negative signals converging

Valuation

7

Overpriced

Momentum

25

Weakening

Sentiment

39

Bearish

Risk resilience

36

High Risk

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Company profile

Company website

aTyr Pharma, Inc., a biopharmaceutical firm established in San Diego, California, in 2005, is dedicated to the discovery and advancement of therapeutic solutions. Operating within the United States, the company's research focuses on pioneering novel immunological pathways to address various medical conditions. Its primary investigational drug, efzofitimod, functions as a selective modulator of NRP2. This compound is currently undergoing a Phase III clinical trial for pulmonary sarcoidosis. Additionally, efzofitimod is being evaluated in a Phase 1b/2a clinical study for the treatment of other interstitial lung diseases (ILDs), including conditions such as chronic hypersensitivity pneumonitis and ILDs linked to connective tissue diseases. Beyond its lead candidate, aTyr Pharma's pipeline features ATYR0101, a fusion protein derived from a domain of aspartyl-tRNA synthetase, which is in preclinical stages of development for combating fibrosis. The company is also progressing with ATYR0750, a domain sourced from alanyl-tRNA synthetase, intended for the management of liver disorders. Furthermore, aTyr Pharma has entered into a strategic collaboration and licensing agreement with Kyorin Pharmaceutical Co., Ltd. This partnership is focused on the development and commercialization of efzofitimod for interstitial lung diseases specifically within the Japanese market.

Industry
Biotechnology
Sector
Healthcare
Headquarters
US
CEO
Sanjay S. Shukla
Listed since
May 7, 2015
Employees
58

Market position

Day range

Current $0.5015

52-week range

Current $0.5015

Open
$0.5138
Previous close
$0.503
Volume
522.71K
0.25× average
Average volume
2.13M
Average daily volume
Market cap
49.17M USD
Beta
0.52
Market reference 1
50-day average
$0.5201
-3.57% below average
200-day average
$0.708
-29.17% below average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
74.11M USD
EV / EBITDA
-1.02×
Earnings yield
-101.79%
Free cash flow yield
-85.23%

Profitability & efficiency

Return on equity
-109.84%
Return on assets
-78.71%
Return on invested capital
-96.45%

Financial health

Current ratio
5.3×

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends4196%-12187%-28569%-44952%Gross margin, FY2022: 83.68%Gross margin, FY2023: 100.00%Gross margin, FY2024: 100.00%Gross margin, FY2025: -717.37%Operating margin, FY2022: -446.79%Operating margin, FY2023: -15557.79%Operating margin, FY2024: -28899.57%Operating margin, FY2025: -40856.32%Net margin, FY2022: -436.53%Net margin, FY2023: -14274.50%Net margin, FY2024: -27243.83%Net margin, FY2025: -39009.47%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2022 83.68%. Gross margin FY2023 100.00%. Gross margin FY2024 100.00%. Gross margin FY2025 -717.37%. Operating margin FY2022 -446.79%. Operating margin FY2023 -15557.79%. Operating margin FY2024 -28899.57%. Operating margin FY2025 -40856.32%. Net margin FY2022 -436.53%. Net margin FY2023 -14274.50%. Net margin FY2024 -27243.83%. Net margin FY2025 -39009.47%.

Income trends

Revenue

190K USD-19.15%

Operating income

−77.63M USD-14.30%

Net income

−74.12M USD-15.77%
Income trends across reported periods19.19M USD−16.02M USD−51.22M USD−86.43M USDRevenue, FY2022: 10.39M USDRevenue, FY2023: 353K USDRevenue, FY2024: 235K USDRevenue, FY2025: 190K USDOperating income, FY2021: −34.02M USDOperating income, FY2022: −46.4M USDOperating income, FY2023: −54.92M USDOperating income, FY2024: −67.91M USDOperating income, FY2025: −77.63M USDNet income, FY2021: −33.77M USDNet income, FY2022: −45.34M USDNet income, FY2023: −50.39M USDNet income, FY2024: −64.02M USDNet income, FY2025: −74.12M USDFY2021FY2022FY2023FY2024FY2025
Revenue FY2022 10.39M USD. Revenue FY2023 353K USD. Revenue FY2024 235K USD. Revenue FY2025 190K USD. Operating income FY2021 −34.02M USD. Operating income FY2022 −46.4M USD. Operating income FY2023 −54.92M USD. Operating income FY2024 −67.91M USD. Operating income FY2025 −77.63M USD. Net income FY2021 −33.77M USD. Net income FY2022 −45.34M USD. Net income FY2023 −50.39M USD. Net income FY2024 −64.02M USD. Net income FY2025 −74.12M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Revenue190K USD235K USD353K USD10.39M USD
Cost of goods sold1.55M USD1.7M USD1.3M USD
Gross profit−1.36M USD235K USD353K USD8.69M USD−1.3M USD
Research and development60.22M USD54.37M USD42.29M USD42.81M USD23.26M USD
Selling, general, and administrative17.6M USD13.78M USD12.98M USD12.29M USD10.75M USD
Operating expenses76.26M USD68.15M USD55.27M USD55.1M USD32.71M USD
Depreciation and amortization1.55M USD1.54M USD2.74M USD1.7M USD1.3M USD
Operating income−77.63M USD−67.91M USD−54.92M USD−46.4M USD−34.02M USD
Net income−74.12M USD−64.02M USD−50.39M USD−45.34M USD−33.77M USD

Company facts updated Aug 24, 2026.

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