Anavex Life Sciences Corp. logo

Anavex Life Sciences Corp.

AVXL

NASDAQHealthcareBiotechnology

Previous close

$3.24

+$0.11 · +3.51%

Aug 21, 4:00 PM ET

AVXL company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Sell

Trim exposure — unfavorable risk-reward

Valuation

40

Expensive

Momentum

22

Weakening

Sentiment

40

Bearish

Risk resilience

30

High Risk

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Company profile

Company website

Operating as a clinical-stage biopharmaceutical entity, Anavex Life Sciences Corp. specializes in developing therapeutic drug candidates for various central nervous system (CNS) conditions. Its leading compound, ANAVEX 2-73, is currently in advanced development, undergoing Phase III clinical evaluation for both Alzheimer's disease and pediatric Rett syndrome. This same drug is also in Phase II trials for Parkinson's disease and is being explored in preclinical studies for a wider range of disorders, including epilepsy, infantile spasms, Fragile X syndrome, Angelman syndrome, multiple sclerosis, and tuberous sclerosis complex. Another significant drug candidate, ANAVEX 3-71, has progressed to Phase I clinical trials for frontotemporal dementia and other forms of dementia, with additional preclinical investigation underway for neurodegenerative illnesses like Alzheimer's and Parkinson's. The company's earlier-stage portfolio includes ANAVEX 1-41, a sigma-1 receptor agonist targeting depression, stroke, Parkinson's, and Alzheimer's diseases; ANAVEX 1066, a mixed sigma-1/sigma-2 ligand with potential applications in neuropathic and visceral pain; and ANAVEX 1037, aimed at treating prostate and pancreatic cancers. Anavex Life Sciences Corp. was founded in 2004 and maintains its headquarters in New York, New York.

Industry
Biotechnology
Sector
Healthcare
Headquarters
US
CEO
Terrie Kellmeyer
Listed since
Aug 2, 2006
Employees
34

Market position

Day range

Current $3.24

52-week range

Current $3.24

Open
$3.165
Previous close
$3.13
Volume
480.79K
0.44× average
Average volume
1.1M
Average daily volume
Market cap
300.26M USD
Beta
1.14
Market reference 1
50-day average
$2.766
+17.14% above average
200-day average
$3.6516
-11.27% below average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
656.5M USD
P/E (TTM)
-8.28×
P/B (TTM)
2.47×
P/S (TTM)
EV / EBITDA
-14.16×
Earnings yield
-6.11%
Free cash flow yield
-5.14%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
0.00%
Operating margin
0.00%
Net margin
0.00%
Return on equity
-48.89%
Return on assets
-44.67%
Return on invested capital
-54.19%

Financial health

Debt / equity
Current ratio
11.6×
Altman Z-score
21.53
Piotroski F-score
2 of 9

Financial statements

Income trends

Operating income

−51.41M USD+2.78%

Net income

−46.38M USD-7.85%
Income trends across reported periods−36.12M USD−43.27M USD−50.41M USD−57.55M USDOperating income, FY2021: −42M USDOperating income, FY2022: −50.99M USDOperating income, FY2023: −55.76M USDOperating income, FY2024: −52.88M USDOperating income, FY2025: −51.41M USDNet income, FY2021: −37.91M USDNet income, FY2022: −47.98M USDNet income, FY2023: −47.51M USDNet income, FY2024: −43M USDNet income, FY2025: −46.38M USDFY2021FY2022FY2023FY2024FY2025
Operating income FY2021 −42M USD. Operating income FY2022 −50.99M USD. Operating income FY2023 −55.76M USD. Operating income FY2024 −52.88M USD. Operating income FY2025 −51.41M USD. Net income FY2021 −37.91M USD. Net income FY2022 −47.98M USD. Net income FY2023 −47.51M USD. Net income FY2024 −43M USD. Net income FY2025 −46.38M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Research and development37.59M USD41.84M USD43.72M USD37.92M USD32.98M USD
Selling, general, and administrative13.82M USD11.04M USD12.05M USD13.07M USD9.02M USD
Operating expenses51.41M USD52.88M USD55.76M USD50.99M USD42M USD
Interest income4.68M USD7.32M USD6.52M USD947K USD26K USD
Interest expense964K USD
Operating income−51.41M USD−52.88M USD−55.76M USD−50.99M USD−42M USD
Net income−46.38M USD−43M USD−47.51M USD−47.98M USD−37.91M USD

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
82%
9 beats, 2 misses, 0 met estimates
Average EPS surprise
+12.90%
11 comparable reports
Latest EPS result
-0.06
Estimate -0.08 · Beat by 25.00%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates-0.05-0.1-0.16-0.21Q4 '24BeatQ1 '25BeatQ2 '25BeatQ3 '25MissQ4 '25BeatQ1 '26BeatQ3 '26BeatQ4 '26Estimate
Q4 2024, reported Dec 23, 2024: actual -0.14, estimate -0.16, surprise +12.50%, Beat. Q1 2025, reported Feb 12, 2025: actual -0.14, estimate -0.17, surprise +17.65%, Beat. Q2 2025, reported May 13, 2025: actual -0.13, estimate -0.16, surprise +18.75%, Beat. Q3 2025, reported Aug 12, 2025: actual -0.16, estimate -0.13, surprise -23.08%, Miss. Q4 2025, reported Nov 25, 2025: actual -0.11, estimate -0.13, surprise +15.38%, Beat. Q1 2026, reported Feb 9, 2026: actual -0.06, estimate -0.1, surprise +40.00%, Beat. Q3 2026, reported Aug 24, 2026: actual -0.06, estimate -0.08, surprise +25.00%, Beat. Q4 2026, reported Nov 30, 2026: actual —, estimate -0.08, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates116.84M91.31M65.78M40.25MQ4 '24EstimateQ2 '25EstimateQ3 '25EstimateQ4 '25Estimate
Q4 2024, reported Dec 23, 2024: actual —, estimate 45.92M USD, surprise —, Comparison unavailable. Q2 2025, reported May 13, 2025: actual —, estimate 45.53M USD, surprise —, Comparison unavailable. Q3 2025, reported Aug 12, 2025: actual —, estimate 71.73M USD, surprise —, Comparison unavailable. Q4 2025, reported Nov 25, 2025: actual —, estimate 111.56M USD, surprise —, Comparison unavailable.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Analyst price target

Average target

$11.00

239.51% upside
Past 12 months12-month forecastHigh $11.00Average $11.00Low $11.00

Rating distribution

13 ratings
Strong buy00%
Buy1185%
Hold215%
Sell00%
Strong sell00%

Recent analyst actions

4 institutions
Jones TradingdowngradeBuyHold

AVXL news

Corporate actions

Corporate action history

Stock split

Effective Oct 7, 2015

1:4

AVXL peers

ETFs holding AVXL

Funds reporting this stock among their holdings, ordered by reported position size.

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