
Axsome Therapeutics, Inc.
AXSMNASDAQHealthcareBiotechnology
Previous close
$207.77
−$0.26 · -0.12%
AXSM company overview
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GoAI snapshot
AI-powered factor overview
GoAI score
Buy
Favorable setup — positive multi-factor alignment
Valuation
66
Undervalued
Momentum
59
Neutral
Sentiment
64
Bullish
Risk resilience
73
Moderate Risk
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Company profile
Company websiteAxsome Therapeutics, Inc. is a biopharmaceutical company dedicated to discovering and advancing innovative treatments for a range of central nervous system (CNS) disorders within the United States. Its robust product pipeline features several promising candidates, including: AXS-05, an investigational therapy currently being developed for major depressive disorder and treatment-resistant depression. This compound is also in Phase III clinical evaluation for Alzheimer's disease agitation and has successfully finished Phase II trials investigating its use for smoking cessation. AXS-07, a novel, orally administered, rapidly-acting investigational medicine that employs multiple mechanisms of action. It has concluded two Phase III studies for the acute treatment of migraine attacks. AXS-12, a selective and potent norepinephrine reuptake inhibitor, which is presently undergoing a Phase III trial for narcolepsy. AXS-14, an oral investigational drug, advancing through Phase III trials for the management of fibromyalgia. Axsome Therapeutics also engages in a research collaboration with Duke University to further assess AXS-05's potential in smoking cessation. The company, established in 2012, has its main offices in New York, New York.
- Industry
- Biotechnology
- Sector
- Healthcare
- Headquarters
- US
- CEO
- Herriot Tabuteau
- Listed since
- Nov 19, 2015
- Employees
- 1,346
Market position
Day range
Current $207.77
52-week range
Current $207.77
- Open
- $209.33
- Previous close
- $208.03
- Volume
- 734.95K
- 0.86× average
- Average volume
- 858.64K
- Average daily volume
- Market cap
- 10.69B USD
- Beta
- 0.6
- Market reference 1
- 50-day average
- $232.4
- -10.60% below average
- 200-day average
- $191.43
- +8.54% above average
Financials
Financial snapshot
Latest / TTMValuation & yield
- Enterprise value
- 9B USD
- P/E (TTM)
- -55.41×
- P/B (TTM)
- 128.45×
- P/S (TTM)
- 13.77×
- EV / EBITDA
- -53.57×
- Earnings yield
- -2.02%
- Free cash flow yield
- -1.03%
- Dividend yield
- 0.00%
Profitability & efficiency
- Gross margin
- 93.24%
- Operating margin
- -24.28%
- Net margin
- -24.68%
- Return on equity
- -207.46%
- Return on assets
- -26.55%
- Return on invested capital
- -43.95%
Financial health
- Debt / equity
- 2.63×
- Current ratio
- 1.55×
Financial statements
Margin trends
Profitability as a percentage of reported revenue.
Income trends
Revenue
Operating income
Net income
| Metric (USD) | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 |
|---|---|---|---|---|---|
| Revenue | 638.5M USD | 385.69M USD | 270.6M USD | 50.04M USD | — |
| Cost of goods sold | 47.48M USD | 33.3M USD | 26.07M USD | 5.2M USD | — |
| Gross profit | 591.02M USD | 352.39M USD | 244.54M USD | 44.84M USD | — |
| Research and development | 183.28M USD | 187.08M USD | 97.94M USD | 57.95M USD | 58.06M USD |
| Selling, general, and administrative | 570.6M USD | 411.36M USD | 323.12M USD | 159.25M USD | 66.65M USD |
| Operating expenses | 760.25M USD | 632.95M USD | 476.36M USD | 224.64M USD | 124.71M USD |
| Interest income | 9.37M USD | — | — | — | — |
| Interest expense | 6.56M USD | 6.57M USD | 6.45M USD | 7.34M USD | 5.7M USD |
| Depreciation and amortization | 9.06M USD | 7.96M USD | 6.83M USD | 4.4M USD | 76K USD |
| Operating income | −169.24M USD | −280.56M USD | −231.83M USD | −179.8M USD | −124.71M USD |
| Net income | −183.17M USD | −287.22M USD | −239.24M USD | −187.13M USD | −130.4M USD |
Company facts updated Aug 24, 2026.
Analyst ratings
Third-party consensus; not a GoAI recommendation.
Analyst price target
Average target
$282.53
35.98% upsideRating distribution
26 ratingsAXSM peers
ETFs holding AXSM
Funds reporting this stock among their holdings, ordered by reported position size.
Vanguard Morningstar Total Stock Market ETFVTI303.75M0.01%2.3T USD0.03%$378.24+0.44%
Vanguard Morningstar Small-Cap ETFVB219.08M0.12%183.4B USD0.03%$304.76+0.64%
Vanguard Morningstar Small-Cap Growth ETFVBK126.83M0.28%43.8B USD0.05%$358.65+0.70%
Vanguard Extended Market ETFVXF108.47M0.11%93.7B USD0.05%$245.53+0.82%
First Trust NYSE Arca Biotechnology Index FundFBT80.19M2.76%2.94B USD0.55%$271.07+1.10%
iShares Biotechnology ETFIBB66.98M0.63%10.75B USD0.44%$213.56+1.29%
iShares Russell Mid-Cap Growth ETFIWP51.64M0.25%20.62B USD0.23%$143.66+0.99%
Schwab U.S. Small-Cap ETFSCHA42.98M0.19%23.1B USD0.03%$34.83+0.52%
Vanguard Morningstar Total Stock Market ETFVTI- Market value
- 303.75M
- Weight
- 0.01%
- AUM
- 2.3T USD
- Expense ratio
- 0.03%
- Price / 1D
- $378.24+0.44%
Vanguard Morningstar Small-Cap ETFVB- Market value
- 219.08M
- Weight
- 0.12%
- AUM
- 183.4B USD
- Expense ratio
- 0.03%
- Price / 1D
- $304.76+0.64%
Vanguard Morningstar Small-Cap Growth ETFVBK- Market value
- 126.83M
- Weight
- 0.28%
- AUM
- 43.8B USD
- Expense ratio
- 0.05%
- Price / 1D
- $358.65+0.70%
Vanguard Extended Market ETFVXF- Market value
- 108.47M
- Weight
- 0.11%
- AUM
- 93.7B USD
- Expense ratio
- 0.05%
- Price / 1D
- $245.53+0.82%
First Trust NYSE Arca Biotechnology Index FundFBT- Market value
- 80.19M
- Weight
- 2.76%
- AUM
- 2.94B USD
- Expense ratio
- 0.55%
- Price / 1D
- $271.07+1.10%
iShares Biotechnology ETFIBB- Market value
- 66.98M
- Weight
- 0.63%
- AUM
- 10.75B USD
- Expense ratio
- 0.44%
- Price / 1D
- $213.56+1.29%
iShares Russell Mid-Cap Growth ETFIWP- Market value
- 51.64M
- Weight
- 0.25%
- AUM
- 20.62B USD
- Expense ratio
- 0.23%
- Price / 1D
- $143.66+0.99%
Schwab U.S. Small-Cap ETFSCHA- Market value
- 42.98M
- Weight
- 0.19%
- AUM
- 23.1B USD
- Expense ratio
- 0.03%
- Price / 1D
- $34.83+0.52%
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