Cue Biopharma, Inc. is a clinical-stage biopharmaceutical enterprise focused on creating biological therapies. Its central objective is the precise manipulation of the human immune system to address a spectrum of severe conditions, such as various cancers, chronic infectious diseases, and autoimmune disorders. The company's leading investigational therapeutic is CUE-101, a specialized fusion protein biologic. This candidate is currently advancing through Phase 1b clinical trials, engineered to specifically identify and activate antigen-specific T cells involved in cancers originating from human papillomavirus. Beyond its flagship program, Cue Biopharma is also developing a range of other innovative platforms: CUE-102, another fusion protein biologic designed to stimulate specific T cells to combat cancer; CUE-103, an Immuno-STAT from the CUE-100 series, which is developed to target the KRAS G12V mutation relevant in diseases like colorectal, lung, and pancreatic cancers; CUE-200, which concentrates on cell surface receptors such as CD80 and/or 4-1BBL to counteract T cell exhaustion often seen in chronic infections; and the CUE-300 and CUE-400 frameworks, conceptual platforms aimed at treating diverse autoimmune conditions. Cue Biopharma maintains key strategic alliances, including collaborations with Merck Sharp & Dohme Corp. for the research and development of its unique biologics targeting autoimmune indications, with LG Chem Life Sciences for advancing Immuno-STATs in the field of oncology, and with the Albert Einstein College of Medicine. The company, founded in 2014, was initially known as Imagen Biopharma, Inc. before adopting its current name, Cue Biopharma, Inc., in October 2016. It is headquartered in Cambridge, Massachusetts.
Previous close
$22.33
−$0.18 · -0.80%
Pre-market
$21.6192
−$0.7108 · -3.18%
Oct 9, 7:29 AM ET
Regular session · ET · Market data may be delayed.
Cue Biopharma, Inc. is a clinical-stage biopharmaceutical enterprise focused on creating biological therapies. Its central objective is the precise manipulation of the human immune system to address a spectrum of severe conditions, such as various cancers, chronic infectious diseases, and autoimmune disorders. The company's leading investigational therapeutic is CUE-101, a specialized fusion protein biologic. This candidate is currently advancing through Phase 1b clinical trials, engineered to specifically identify and activate antigen-specific T cells involved in cancers originating from human papillomavirus. Beyond its flagship program, Cue Biopharma is also developing a range of other innovative platforms: CUE-102, another fusion protein biologic designed to stimulate specific T cells to combat cancer; CUE-103, an Immuno-STAT from the CUE-100 series, which is developed to target the KRAS G12V mutation relevant in diseases like colorectal, lung, and pancreatic cancers; CUE-200, which concentrates on cell surface receptors such as CD80 and/or 4-1BBL to counteract T cell exhaustion often seen in chronic infections; and the CUE-300 and CUE-400 frameworks, conceptual platforms aimed at treating diverse autoimmune conditions. Cue Biopharma maintains key strategic alliances, including collaborations with Merck Sharp & Dohme Corp. for the research and development of its unique biologics targeting autoimmune indications, with LG Chem Life Sciences for advancing Immuno-STATs in the field of oncology, and with the Albert Einstein College of Medicine. The company, founded in 2014, was initially known as Imagen Biopharma, Inc. before adopting its current name, Cue Biopharma, Inc., in October 2016. It is headquartered in Cambridge, Massachusetts.
Day range
Current $22.33
52-week range
Current $22.33
Regular session · ET · Market data may be delayed.
GoAI Score
Hold
Valuation
71
Undervalued
Sentiment
54
Mixed
Risk
63
High Risk
Momentum
65
Gaining
Full GoAI research
Thesis, catalysts, evidence, and risk analysis.
Cue Biopharma, Inc. is a clinical-stage biopharmaceutical enterprise focused on creating biological therapies. Its central objective is the precise manipulation of the human immune system to address a spectrum of severe conditions, such as various cancers, chronic infectious diseases, and autoimmune disorders. The company's leading investigational therapeutic is CUE-101, a specialized fusion protein biologic. This candidate is currently advancing through Phase 1b clinical trials, engineered to specifically identify and activate antigen-specific T cells involved in cancers originating from human papillomavirus. Beyond its flagship program, Cue Biopharma is also developing a range of other innovative platforms: CUE-102, another fusion protein biologic designed to stimulate specific T cells to combat cancer; CUE-103, an Immuno-STAT from the CUE-100 series, which is developed to target the KRAS G12V mutation relevant in diseases like colorectal, lung, and pancreatic cancers; CUE-200, which concentrates on cell surface receptors such as CD80 and/or 4-1BBL to counteract T cell exhaustion often seen in chronic infections; and the CUE-300 and CUE-400 frameworks, conceptual platforms aimed at treating diverse autoimmune conditions. Cue Biopharma maintains key strategic alliances, including collaborations with Merck Sharp & Dohme Corp. for the research and development of its unique biologics targeting autoimmune indications, with LG Chem Life Sciences for advancing Immuno-STATs in the field of oncology, and with the Albert Einstein College of Medicine. The company, founded in 2014, was initially known as Imagen Biopharma, Inc. before adopting its current name, Cue Biopharma, Inc., in October 2016. It is headquartered in Cambridge, Massachusetts.
Day range
Current $22.33
52-week range
Current $22.33
Profitability as a percentage of reported revenue.
Revenue
Operating income
Net income
| Metric (USD) | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 |
|---|---|---|---|---|---|
| Revenue | 27.47M USD | 9.29M USD | 5.49M USD | 1.25M USD | 14.94M USD |
| Cost of goods sold | — | — | 38.1M USD | — | −1.78M USD |
| Gross profit | 27.47M USD | 9.29M USD | −32.61M USD | 1.25M USD | 16.72M USD |
| Research and development | 37.74M USD | 36.3M USD | 40.8M USD | 38.58M USD | 41.35M USD |
| Selling, general, and administrative | 16.24M USD | 14.59M USD | 16.68M USD | 16.17M USD | 17.31M USD |
| Operating expenses | 53.99M USD | 50.79M USD | 19.54M USD | 54.47M USD | 60.43M USD |
| Interest income | 807K USD | 1.62M USD | 2.66M USD | 928.24K USD | 45.9K USD |
| Interest expense | 357K USD | 796K USD | 1.25M USD | 713.82K USD | — |
| Depreciation and amortization | 958K USD | 2.35M USD | 3.44M USD | 1.81M USD | −1.78M USD |
| Operating income | −26.52M USD | −41.5M USD | −52.15M USD | −53.23M USD | −43.71M USD |
| Net income | −26.6M USD | −40.67M USD | −50.73M USD | −53.01M USD | −44.16M USD |
Company facts updated Oct 9, 2026.
Recent quarterly results
Recent quarterly results
Third-party consensus; not a GoAI recommendation.
Funds reporting this stock among their holdings, ordered by reported position size.
Vanguard Morningstar Total Stock Market ETFVTI2.85M0.00%2.3T USD0.03%$379.56-0.39%
Vanguard Extended Market ETFVXF1.2M0.00%95.4B USD0.05%$233.13-0.15%
iShares Micro-Cap ETFIWC194.44K0.01%1.32B USD0.60%$182.79-0.31%
Avantis U.S. Small Cap Equity ETFAVSC6.78K—3.04B USD0.25%$69.96+0.47%
Avantis Total Equity Markets ETF 1AVTM225.1—790.12M USD0.23%$55.24-0.56%
Vanguard Morningstar Total Stock Market ETFVTI
Vanguard Extended Market ETFVXF
iShares Micro-Cap ETFIWC
Avantis U.S. Small Cap Equity ETFAVSC
Avantis Total Equity Markets ETF 1AVTMAI-generated and delayed market data for informational and educational purposes only. Not investment advice.