Dyadic International, Inc. logo

Dyadic International, Inc.

DYAI

NASDAQHealthcareBiotechnology

Previous close

$0.69

−$0.01 · -1.43%

Aug 21, 4:00 PM ET

DYAI company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Sell

Trim exposure — unfavorable risk-reward

Valuation

34

Expensive

Momentum

52

Neutral

Sentiment

44

Mixed

Risk resilience

41

Elevated Risk

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Company profile

Company website

Dyadic International, Inc. operates as a U.S.-based biotechnology platform company, specializing in the development, production, and commercialization of enzymes and other proteins. Its core activities are underpinned by a patented and proprietary C1 platform, alongside other advanced technologies. This technological foundation drives their research, development, and commercial endeavors, focusing on the creation and manufacturing of various human and animal vaccines and pharmaceutical products. These offerings span a wide range of biological therapeutics, including virus-like particles (VLPs), antigens, monoclonal, bi-specific, and tri-specific antibodies, Fab antibody fragments, Fc-fusion proteins, biosimilars, biobetters, and diverse therapeutic enzymes and proteins. A key pipeline asset is DYAI-100, a SARS-CoV-2-RBD antigen vaccine candidate. This candidate is currently slated for a first-in-human Phase 1 clinical trial, with the objective of establishing proof of concept for the development of next-generation, multivariant COVID-19 vaccine candidates. Dyadic also maintains several strategic alliances, including a research and development agreement with VTT Technical Research Centre of Finland, Ltd., a strategic research services agreement with Biotechnology Developments for Industry in Pharmaceuticals, S.L.U., and a collaboration with Syngene International Limited. Established in 1979, the company is headquartered in Jupiter, Florida.

Industry
Biotechnology
Sector
Healthcare
Headquarters
US
CEO
Mark A. Emalfarb
Listed since
Jan 16, 2008
Employees
5

Market position

Day range

Current $0.69

52-week range

Current $0.69

Open
$0.708
Previous close
$0.70
Volume
116.18K
0.43× average
Average volume
272.82K
Average daily volume
Market cap
25.14M USD
Beta
1.15
Market reference 1
50-day average
$0.9652
-28.51% below average
200-day average
$0.8791
-21.51% below average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
31.11M USD
EV / EBITDA
-4.5×
Earnings yield
-24.01%
Free cash flow yield
-18.59%

Profitability & efficiency

Return on equity
-597.58%
Return on assets
-74.05%
Return on invested capital
-113.55%

Financial health

Current ratio
2.68×
Altman Z-score
-21.84
Piotroski F-score
3 of 9

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends134%-138%-409%-681%Gross margin, FY2021: 19.11%Gross margin, FY2022: 27.54%Gross margin, FY2023: 31.84%Gross margin, FY2024: 65.82%Gross margin, FY2025: -88.25%Operating margin, FY2021: -612.67%Operating margin, FY2022: -346.92%Operating margin, FY2023: -283.90%Operating margin, FY2024: -168.82%Operating margin, FY2025: -579.88%Net margin, FY2021: -543.73%Net margin, FY2022: -332.23%Net margin, FY2023: -234.42%Net margin, FY2024: -166.19%Net margin, FY2025: -597.63%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2021 19.11%. Gross margin FY2022 27.54%. Gross margin FY2023 31.84%. Gross margin FY2024 65.82%. Gross margin FY2025 -88.25%. Operating margin FY2021 -612.67%. Operating margin FY2022 -346.92%. Operating margin FY2023 -283.90%. Operating margin FY2024 -168.82%. Operating margin FY2025 -579.88%. Net margin FY2021 -543.73%. Net margin FY2022 -332.23%. Net margin FY2023 -234.42%. Net margin FY2024 -166.19%. Net margin FY2025 -597.63%.

Income trends

Revenue

1.23M USD-64.74%

Operating income

−7.15M USD-21.10%

Net income

−7.36M USD-26.78%
Income trends across reported periods5.32M USD−1.97M USD−9.26M USD−16.55M USDRevenue, FY2021: 2.4M USDRevenue, FY2022: 2.93M USDRevenue, FY2023: 2.9M USDRevenue, FY2024: 3.5M USDRevenue, FY2025: 1.23M USDOperating income, FY2021: −14.73M USDOperating income, FY2022: −10.17M USDOperating income, FY2023: −8.23M USDOperating income, FY2024: −5.9M USDOperating income, FY2025: −7.15M USDNet income, FY2021: −13.07M USDNet income, FY2022: −9.74M USDNet income, FY2023: −6.8M USDNet income, FY2024: −5.81M USDNet income, FY2025: −7.36M USDFY2021FY2022FY2023FY2024FY2025
Revenue FY2021 2.4M USD. Revenue FY2022 2.93M USD. Revenue FY2023 2.9M USD. Revenue FY2024 3.5M USD. Revenue FY2025 1.23M USD. Operating income FY2021 −14.73M USD. Operating income FY2022 −10.17M USD. Operating income FY2023 −8.23M USD. Operating income FY2024 −5.9M USD. Operating income FY2025 −7.15M USD. Net income FY2021 −13.07M USD. Net income FY2022 −9.74M USD. Net income FY2023 −6.8M USD. Net income FY2024 −5.81M USD. Net income FY2025 −7.36M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Revenue1.23M USD3.5M USD2.9M USD2.93M USD2.4M USD
Cost of goods sold2.32M USD1.19M USD1.98M USD2.12M USD1.94M USD
Gross profit−1.09M USD2.3M USD922.96K USD807.11K USD459.39K USD
Research and development2.15M USD2.04M USD3.3M USD4.5M USD8.39M USD
Selling, general, and administrative5.76M USD6.13M USD5.82M USD6.42M USD6.7M USD
Operating expenses6.06M USD8.2M USD9.15M USD10.97M USD15.19M USD
Interest income284.09K USD456.99K USD416.69K USD180.42K USD51.7K USD
Interest expense455.9K USD427.97K USD
Depreciation and amortization38.42K USD3.49M USD
Operating income−7.15M USD−5.9M USD−8.23M USD−10.17M USD−14.73M USD
Net income−7.36M USD−5.81M USD−6.8M USD−9.74M USD−13.07M USD

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
11%
1 beat, 6 misses, 2 met estimates
Average EPS surprise
-22.22%
9 comparable reports
Latest EPS result
-0.06
Estimate -0.04 · Miss by 71.43%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates-0.03-0.05-0.08-0.11Q1 '25MissQ2 '25No estimateQ3 '25MetQ4 '25MissQ1 '26MissQ2 '26MissQ3 '26MissQ4 '26Estimate
Q1 2025, reported Mar 26, 2025: actual -0.05, estimate -0.04, surprise -25.00%, Miss. Q2 2025, reported May 14, 2025: actual -0.07, estimate —, surprise —, Comparison unavailable. Q3 2025, reported Aug 13, 2025: actual -0.06, estimate -0.06, surprise 0.00%, Met estimate. Q4 2025, reported Nov 12, 2025: actual -0.06, estimate -0.04, surprise -50.00%, Miss. Q1 2026, reported Mar 25, 2026: actual -0.06, estimate -0.03, surprise -100.00%, Miss. Q2 2026, reported May 13, 2026: actual -0.05, estimate -0.04, surprise -25.00%, Miss. Q3 2026, reported Aug 12, 2026: actual -0.06, estimate -0.035, surprise -71.43%, Miss. Q4 2026, reported Nov 11, 2026: actual —, estimate -0.03, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates1.7M1.24M788.53K334.54KQ1 '25MissQ2 '25No estimateQ3 '25MissQ4 '25MissQ1 '26MissQ2 '26BeatQ3 '26MissQ4 '26Estimate
Q1 2025, reported Mar 26, 2025: actual 817.38K USD, estimate 1.6M USD, surprise -48.91%, Miss. Q2 2025, reported May 14, 2025: actual 393.57K USD, estimate —, surprise —, Comparison unavailable. Q3 2025, reported Aug 13, 2025: actual 463.45K USD, estimate 1.5M USD, surprise -69.10%, Miss. Q4 2025, reported Nov 12, 2025: actual 1.16M USD, estimate 1.34M USD, surprise -13.30%, Miss. Q1 2026, reported Mar 25, 2026: actual 564.35K USD, estimate 1.34M USD, surprise -57.99%, Miss. Q2 2026, reported May 13, 2026: actual 1.11M USD, estimate 903.75K USD, surprise +22.93%, Beat. Q3 2026, reported Aug 12, 2026: actual 961.14K USD, estimate 1.03M USD, surprise -6.27%, Miss. Q4 2026, reported Nov 11, 2026: actual —, estimate 1.43M USD, surprise —, Comparison unavailable.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Analyst price target

Average target

$3.00

334.78% upside
Past 12 months12-month forecast

Price history unavailable

High $3.00Average $3.00Low $3.00

DYAI peers

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