Fractyl Health, Inc. logo

Fractyl Health, Inc.

GUTS

NASDAQHealthcareBiotechnology

Previous close

$0.78

+$0.0949 · +13.85%

Aug 21, 4:00 PM ET

GUTS company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Sell

Trim exposure — unfavorable risk-reward

Valuation

21

Expensive

Momentum

26

Weakening

Sentiment

43

Mixed

Risk resilience

20

High Risk

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Company profile

Company website

Fractyl Health, Inc., a metabolic therapeutics company, develops therapies for the treatment of type 2 diabetes (T2D) and obesity. The company develops Revita DMR System (Revita), an outpatient procedural therapy designed to durably modify duodenal dysfunction, a pathologic consequence of a high fat and high sugar diet, which can initiate T2D and obesity in humans. It develops Rejuva, a novel adeno-associated virus delivered pancreatic gene therapy platform that is designed to enable long-term remission of T2D and obesity by durably altering metabolic hormone function in the pancreatic islet cells of patients. Fractyl Health, Inc. was formerly known as Fractyl Laboratories Inc. and changed its name to Fractyl Health, Inc. on June 09, 2021. The company was incorporated in 2010 and is headquartered in Burlington, Massachusetts.

Industry
Biotechnology
Sector
Healthcare
Headquarters
US
CEO
Harith Rajagopalan
Listed since
Feb 2, 2024
Employees
100

Market position

Day range

Current $0.78

52-week range

Current $0.78

Open
$0.685
Previous close
$0.6851
Volume
3.39M
1.86× average
Average volume
1.83M
Average daily volume
Market cap
123.75M USD
Beta
2.32
Market reference 1
50-day average
$0.7589
+2.77% above average
200-day average
$0.9921
-21.38% below average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
317.52M USD
P/E (TTM)
-0.71×
P/B (TTM)
-74.32×
P/S (TTM)
EV / EBITDA
-2.27×
Earnings yield
-41.77%
Free cash flow yield
-26.94%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
0.00%
Operating margin
0.00%
Net margin
0.00%
Return on equity
-1490.32%
Return on assets
-116.11%
Return on invested capital
-89.50%

Financial health

Debt / equity
-36.48×
Current ratio
4.78×

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends10108%-30139%-70386%-110633%Gross margin, FY2023: 35.83%Gross margin, FY2024: 46.24%Operating margin, FY2023: -42363.33%Operating margin, FY2024: -100570.97%Net margin, FY2023: -64242.50%Net margin, FY2024: -73864.52%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2023 35.83%. Gross margin FY2024 46.24%. Operating margin FY2023 -42363.33%. Operating margin FY2024 -100570.97%. Net margin FY2023 -64242.50%. Net margin FY2024 -73864.52%.

Income trends

Revenue

93K USD-22.50%

Operating income

−96.82M USD-3.51%

Net income

−140.95M USD-105.19%
Income trends across reported periods14.23M USD−42.2M USD−98.63M USD−155.06M USDRevenue, FY2023: 120K USDRevenue, FY2024: 93K USDOperating income, FY2021: −36.93M USDOperating income, FY2022: −49.39M USDOperating income, FY2023: −50.84M USDOperating income, FY2024: −93.53M USDOperating income, FY2025: −96.82M USDNet income, FY2021: −38.74M USDNet income, FY2022: −46.45M USDNet income, FY2023: −77.09M USDNet income, FY2024: −68.69M USDNet income, FY2025: −140.95M USDFY2021FY2022FY2023FY2024FY2025
Revenue FY2023 120K USD. Revenue FY2024 93K USD. Operating income FY2021 −36.93M USD. Operating income FY2022 −49.39M USD. Operating income FY2023 −50.84M USD. Operating income FY2024 −93.53M USD. Operating income FY2025 −96.82M USD. Net income FY2021 −38.74M USD. Net income FY2022 −46.45M USD. Net income FY2023 −77.09M USD. Net income FY2024 −68.69M USD. Net income FY2025 −140.95M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Revenue93K USD120K USD
Cost of goods sold50K USD77K USD452K USD
Gross profit43K USD43K USD−452K USD
Research and development74.54M USD70.47M USD38.04M USD34.35M USD26.44M USD
Selling, general, and administrative22.28M USD14.58M USD10.49M USD
Operating expenses96.82M USD93.57M USD50.88M USD48.93M USD36.93M USD
Interest income1.54M USD4.15M USD1.26M USD797K USD
Interest expense1.44M USD
Depreciation and amortization1.13M USD677K USD286K USD452K USD676K USD
Operating income−96.82M USD−93.53M USD−50.84M USD−49.39M USD−36.93M USD
Net income−140.95M USD−68.69M USD−77.09M USD−46.45M USD−38.74M USD

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
36%
4 beats, 6 misses, 1 met estimate
Average EPS surprise
-165.52%
11 comparable reports
Latest EPS result
-0.12
Estimate -0.14 · Beat by 11.11%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates0.12-0.18-0.47-0.77Q1 '25MissQ2 '25MetQ3 '25MissQ4 '25MissQ1 '26MissQ2 '26BeatQ3 '26BeatQ4 '26Estimate
Q1 2025, reported Mar 3, 2025: actual -0.52, estimate -0.44, surprise -18.18%, Miss. Q2 2025, reported May 13, 2025: actual -0.49, estimate -0.49, surprise 0.00%, Met estimate. Q3 2025, reported Aug 12, 2025: actual -0.53, estimate -0.37, surprise -43.24%, Miss. Q4 2025, reported Nov 12, 2025: actual -0.71, estimate -0.34, surprise -108.82%, Miss. Q1 2026, reported Mar 24, 2026: actual -0.29, estimate -0.19, surprise -52.63%, Miss. Q2 2026, reported May 12, 2026: actual 0.06, estimate -0.17, surprise +135.29%, Beat. Q3 2026, reported Aug 10, 2026: actual -0.12, estimate -0.135, surprise +11.11%, Beat. Q4 2026, reported Nov 11, 2026: actual —, estimate -0.13, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates46.2K31.65K17.1K2.55KQ2 '24No estimateQ2 '24No estimateQ3 '24No estimateQ4 '24BeatQ1 '25Miss
Q2 2024, reported Apr 1, 2024: actual 7K USD, estimate —, surprise —, Comparison unavailable. Q2 2024, reported May 13, 2024: actual 33K USD, estimate —, surprise —, Comparison unavailable. Q3 2024, reported Aug 14, 2024: actual 43K USD, estimate —, surprise —, Comparison unavailable. Q4 2024, reported Nov 12, 2024: actual 14K USD, estimate 10K USD, surprise +40.00%, Beat. Q1 2025, reported Mar 3, 2025: actual 3K USD, estimate 10K USD, surprise -70.00%, Miss.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Analyst price target

Average target

$5.00

541.03% upside
Past 12 months12-month forecastHigh $8.00Average $5.00Low $2.00

Recent analyst actions

3 institutions

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