Heron Therapeutics, Inc. logo

Heron Therapeutics, Inc.

HRTX

NASDAQHealthcareBiotechnology

Latest quote

$0.3158

+$0.0092 · +2.98%

Aug 21, 3:55 PM ET

HRTX company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Sell

Trim exposure — unfavorable risk-reward

Valuation

65

Undervalued

Momentum

19

Strong Down

Sentiment

49

Mixed

Risk resilience

26

High Risk

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Company profile

Company website

Heron Therapeutics, Inc. is a biotechnology firm dedicated to creating innovative therapies for critical patient requirements. The company leverages its proprietary Biochronomer drug delivery platform, an advanced system that enables the controlled release of various short-acting pharmacological agents. This technology ensures therapeutic concentrations are maintained for periods ranging from days to weeks following just a single administration. Among its commercialized products is SUSTOL (granisetron), an extended-release injectable designed to prevent both immediate and delayed nausea and vomiting triggered by moderately emetogenic chemotherapy, or specific anthracycline and cyclophosphamide combination therapies. Additionally, Heron markets CINVANTI, an intravenous formulation of aprepitant. CINVANTI, which acts as a substance P/neurokinin-1 receptor antagonist, is indicated for the prevention of acute and delayed chemotherapy-induced nausea and vomiting in patients undergoing highly or moderately emetogenic cancer chemotherapy. The company's development pipeline includes ZYNRELEF, an innovative dual-acting local anesthetic that combines bupivacaine, a local anesthetic, with a low dose of the nonsteroidal anti-inflammatory drug (NSAID) meloxicam in a single fixed-dose formulation. Also in development is HTX-019, an experimental therapy aimed at preventing postoperative nausea and vomiting (PONV). Furthermore, HTX-034 is being advanced for postoperative pain management and is currently undergoing Phase Ib/II clinical trials, notably in patients recovering from bunionectomy procedures. Originally established in 1983 as A.P. Pharma, Inc., the company adopted its current name, Heron Therapeutics, Inc., in January 2014. Its corporate headquarters are situated in San Diego, California.

Industry
Biotechnology
Sector
Healthcare
Headquarters
US
CEO
Craig Alexander Collard
Listed since
Aug 26, 1987
Employees
128

Market position

Volume
3.02M
0.94× average
Average volume
3.2M
Average daily volume
Market cap
60.23M USD
Beta
1.67
Market reference 1

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
328.71M USD
P/E (TTM)
-1.7×
P/B (TTM)
8.77×
P/S (TTM)
0.4×
EV / EBITDA
-18.38×
Earnings yield
-9.32%
Free cash flow yield
-12.88%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
70.07%
Operating margin
-7.19%
Net margin
-22.52%
Return on equity
-140.90%
Return on assets
-7.89%
Return on invested capital
-1.59%

Financial health

Debt / equity
21.48×
Current ratio
2.48×

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends106%-25%-157%-288%Gross margin, FY2021: 46.70%Gross margin, FY2022: 49.04%Gross margin, FY2023: 48.75%Gross margin, FY2024: 73.21%Gross margin, FY2025: 73.31%Operating margin, FY2021: -252.27%Operating margin, FY2022: -162.21%Operating margin, FY2023: -87.07%Operating margin, FY2024: -7.99%Operating margin, FY2025: -1.64%Net margin, FY2021: -255.58%Net margin, FY2022: -169.05%Net margin, FY2023: -87.02%Net margin, FY2024: -9.41%Net margin, FY2025: -13.04%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2021 46.70%. Gross margin FY2022 49.04%. Gross margin FY2023 48.75%. Gross margin FY2024 73.21%. Gross margin FY2025 73.31%. Operating margin FY2021 -252.27%. Operating margin FY2022 -162.21%. Operating margin FY2023 -87.07%. Operating margin FY2024 -7.99%. Operating margin FY2025 -1.64%. Net margin FY2021 -255.58%. Net margin FY2022 -169.05%. Net margin FY2023 -87.02%. Net margin FY2024 -9.41%. Net margin FY2025 -13.04%.

Income trends

Revenue

154.9M USD+7.36%

Operating income

−2.54M USD+77.98%

Net income

−20.2M USD-48.71%
Income trends across reported periods192.46M USD42.23M USD−108.01M USD−258.24M USDRevenue, FY2021: 86.35M USDRevenue, FY2022: 107.67M USDRevenue, FY2023: 127.04M USDRevenue, FY2024: 144.29M USDRevenue, FY2025: 154.9M USDOperating income, FY2021: −217.83M USDOperating income, FY2022: −174.66M USDOperating income, FY2023: −110.62M USDOperating income, FY2024: −11.53M USDOperating income, FY2025: −2.54M USDNet income, FY2021: −220.68M USDNet income, FY2022: −182.02M USDNet income, FY2023: −110.56M USDNet income, FY2024: −13.58M USDNet income, FY2025: −20.2M USDFY2021FY2022FY2023FY2024FY2025
Revenue FY2021 86.35M USD. Revenue FY2022 107.67M USD. Revenue FY2023 127.04M USD. Revenue FY2024 144.29M USD. Revenue FY2025 154.9M USD. Operating income FY2021 −217.83M USD. Operating income FY2022 −174.66M USD. Operating income FY2023 −110.62M USD. Operating income FY2024 −11.53M USD. Operating income FY2025 −2.54M USD. Net income FY2021 −220.68M USD. Net income FY2022 −182.02M USD. Net income FY2023 −110.56M USD. Net income FY2024 −13.58M USD. Net income FY2025 −20.2M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Revenue154.9M USD144.29M USD127.04M USD107.67M USD86.35M USD
Cost of goods sold41.35M USD38.65M USD65.11M USD54.87M USD46.02M USD
Gross profit113.56M USD105.64M USD61.94M USD52.8M USD40.33M USD
Research and development12.43M USD16.68M USD39.13M USD82.7M USD130.82M USD
Selling, general, and administrative103.67M USD100.48M USD119.82M USD144.75M USD127.33M USD
Operating expenses116.1M USD117.17M USD172.55M USD227.46M USD258.15M USD
Interest income3.55M USD3.36M USD1.64M USD433K USD
Interest expense6.03M USD3.87M USD2.47M USD2.41M USD
Depreciation and amortization2.31M USD2.49M USD2.9M USD2.89M USD3.02M USD
Operating income−2.54M USD−11.53M USD−110.62M USD−174.66M USD−217.83M USD
Net income−20.2M USD−13.58M USD−110.56M USD−182.02M USD−220.68M USD

Company facts updated Aug 24, 2026.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Analyst price target

Average target

$6.67

1996.17% upside
Past 12 months12-month forecastHigh $9.00Average $6.67Low $5.00

Rating distribution

19 ratings
Strong buy00%
Buy1789%
Hold211%
Sell00%
Strong sell00%

HRTX peers

ETFs holding HRTX

Funds reporting this stock among their holdings, ordered by reported position size.

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