Milestone Pharmaceuticals Inc. logo

Milestone Pharmaceuticals Inc.

MIST

NASDAQHealthcareBiotechnology

Previous close

$1.055

+$0.025 · +2.43%

Aug 21, 4:00 PM ET

MIST company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Sell

Trim exposure — unfavorable risk-reward

Valuation

37

Expensive

Momentum

19

Strong Down

Sentiment

31

Bearish

Risk resilience

37

High Risk

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Company profile

Company website

Milestone Pharmaceuticals Inc. is a biopharmaceutical company based in Montréal, Canada, specializing in the creation and commercialization of cardiovascular therapeutics. Their flagship product, etripamil, an innovative channel blocker, is currently in advanced clinical development. It is undergoing Phase III trials for the treatment of paroxysmal supraventricular tachycardia (PSVT) in the United States and Canada, while also progressing through Phase II trials for atrial fibrillation and rapid ventricular rate. Furthermore, Milestone Pharmaceuticals has forged a licensing and collaboration alliance with Ji Xing Pharmaceuticals to advance and distribute etripamil for both preventative and therapeutic applications in humans. The company was founded in 2003.

Industry
Biotechnology
Sector
Healthcare
Headquarters
CA
CEO
Joseph G. Oliveto
Listed since
May 9, 2019
Employees
38

Market position

Day range

Current $1.055

52-week range

Current $1.055

Open
$1.07
Previous close
$1.03
Volume
1.92M
1.31× average
Average volume
1.47M
Average daily volume
Market cap
131.35M USD
Beta
0.98
Market reference 1
50-day average
$1.2116
-12.93% below average
200-day average
$1.6999
-37.94% below average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
154.77M USD
P/E (TTM)
-1.53×
P/B (TTM)
8.03×
P/S (TTM)
56.06×
EV / EBITDA
-2.6×
Earnings yield
-37.21%
Free cash flow yield
-29.12%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
94.58%
Operating margin
-3353.01%
Net margin
-3585.62%
Return on equity
-150.97%
Return on assets
-55.53%
Return on invested capital
-62.00%

Financial health

Debt / equity
3.3×
Current ratio
8.01×

Earnings

EPS beat rate
45%
5 beats, 6 misses, 0 met estimates
Average EPS surprise
-40.91%
11 comparable reports
Latest EPS result
-0.21
Estimate -0.2 · Miss by 7.69%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates0.1-0.05-0.2-0.35Q1 '25MissQ2 '25MissQ3 '25MissQ4 '25BeatQ1 '26BeatQ2 '26MissQ3 '26MissQ4 '26Estimate
Q1 2025, reported Mar 13, 2025: actual -0.19, estimate -0.15, surprise -26.67%, Miss. Q2 2025, reported May 14, 2025: actual -0.31, estimate -0.19, surprise -63.16%, Miss. Q3 2025, reported Aug 12, 2025: actual -0.2, estimate -0.18, surprise -11.11%, Miss. Q4 2025, reported Nov 12, 2025: actual -0.12, estimate -0.17, surprise +29.41%, Beat. Q1 2026, reported Mar 20, 2026: actual -0.16, estimate -0.18, surprise +11.11%, Beat. Q2 2026, reported May 13, 2026: actual -0.2, estimate 0.06, surprise -433.33%, Miss. Q3 2026, reported Aug 12, 2026: actual -0.21, estimate -0.195, surprise -7.69%, Miss. Q4 2026, reported Nov 11, 2026: actual —, estimate -0.2, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates40.59M25.75M10.9M-3.94MQ1 '24No estimateQ1 '26MissQ2 '26MissQ3 '26MissQ4 '26Estimate
Q1 2024, reported Mar 21, 2024: actual -868K USD, estimate —, surprise —, Comparison unavailable. Q1 2026, reported Mar 20, 2026: actual 1.5M USD, estimate 37.52M USD, surprise -96.00%, Miss. Q2 2026, reported May 13, 2026: actual 238K USD, estimate 30.12M USD, surprise -99.21%, Miss. Q3 2026, reported Aug 12, 2026: actual 559K USD, estimate 816.67K USD, surprise -31.55%, Miss. Q4 2026, reported Nov 11, 2026: actual —, estimate 1.14M USD, surprise —, Comparison unavailable.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Analyst price target

Average target

$4.50

326.54% upside
Past 12 months12-month forecastHigh $6.00Average $4.50Low $3.00

Rating distribution

7 ratings
Strong buy00%
Buy686%
Hold114%
Sell00%
Strong sell00%

MIST peers

ETFs holding MIST

Funds reporting this stock among their holdings, ordered by reported position size.

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