Matinas BioPharma Holdings, Inc. logo

Matinas BioPharma Holdings, Inc.

MTNB

AMEXHealthcareBiotechnology

Previous close

$0.1988

+$0.0163 · +8.93%

Aug 21, 4:00 PM ET

Pre-market

$0.1957

−$0.0031 · -1.56%

Aug 24, 8:39 AM ET

MTNB company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Sell

Trim exposure — unfavorable risk-reward

Valuation

25

Expensive

Momentum

54

Neutral

Sentiment

50

Mixed

Risk resilience

22

High Risk

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Company profile

Company website

Matinas BioPharma Holdings, Inc. is a biopharmaceutical firm in the clinical development phase, dedicated to identifying and advancing a range of potential therapeutic products. The company's innovative Lipid Nanocrystal (LNC) platform technology underpins its product development efforts. This sophisticated LNC delivery system leverages lipid nano-crystals to transport a diverse array of therapeutic agents, including small molecules, nucleic acids, gene therapies, vaccines, proteins, and peptides. Its primary experimental drug, LYPDISO, is a proprietary, prescription-grade omega-3 free fatty acid compound engineered to address cardiovascular and metabolic disorders. Matinas BioPharma is also advancing MAT2203, an orally administered version of amphotericin B. This candidate is currently in Phase II clinical trials, where it is being evaluated for its ability to prevent invasive fungal infections in patients undergoing immunosuppressive treatment. Furthermore, MAT2501, an oral formulation of the broad-spectrum aminoglycoside antibiotic amikacin, has successfully completed Phase I clinical trials. Its aim is to combat a spectrum of multidrug-resistant bacterial infections, such as non-tuberculous mycobacterium, multidrug-resistant gram-negative, and intracellular bacterial pathogens. The company actively engages in collaborations, including a research partnership with the National Institute of Allergy and Infectious Diseases (NIAID) to further the development of Gilead's antiviral drug, remdesivir. Additionally, it has a feasibility collaboration with Genentech, Inc. focused on creating new oral drug formulations. Established in 2013, Matinas BioPharma maintains its corporate headquarters in Bedminster, New Jersey.

Industry
Biotechnology
Sector
Healthcare
Headquarters
US
CEO
Jerome D. Jabbour
Listed since
Jul 21, 2014
Employees
2

Market position

Day range

Current $0.1988

52-week range

Current $0.1988

Open
$0.1821
Previous close
$0.1825
Volume
781.93K
0.15× average
Average volume
5.23M
Average daily volume
Market cap
1.27M USD
Beta
1.75
Market reference 1
50-day average
$0.4365
-54.46% below average
200-day average
$0.6304
-68.46% below average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
562.84K USD
P/E (TTM)
-0.16×
P/B (TTM)
0.71×
P/S (TTM)
EV / EBITDA
-0.06×
Earnings yield
-322.49%
Free cash flow yield
-218.56%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
0.00%
Operating margin
0.00%
Net margin
0.00%
Return on equity
-214.18%
Return on assets
-143.52%
Return on invested capital
-108.06%

Financial health

Debt / equity
Current ratio
2.79×

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends7511%-22476%-52464%-82451%Gross margin, FY2021: -44090.91%Gross margin, FY2022: -423.15%Gross margin, FY2023: 14.14%Operating margin, FY2021: -74954.55%Operating margin, FY2022: -771.33%Operating margin, FY2023: -2168.43%Net margin, FY2021: -70554.55%Net margin, FY2022: -658.63%Net margin, FY2023: -2093.25%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2021 -44090.91%. Gross margin FY2022 -423.15%. Gross margin FY2023 14.14%. Operating margin FY2021 -74954.55%. Operating margin FY2022 -771.33%. Operating margin FY2023 -2168.43%. Net margin FY2021 -70554.55%. Net margin FY2022 -658.63%. Net margin FY2023 -2093.25%.

Income trends

Revenue

1.1M USD-65.62%

Operating income

−6.96M USD+65.48%

Net income

−10.35M USD+57.34%
Income trends across reported periods5.98M USD−5.19M USD−16.36M USD−27.53M USDRevenue, FY2021: 33K USDRevenue, FY2022: 3.19M USDRevenue, FY2023: 1.1M USDOperating income, FY2021: −24.74M USDOperating income, FY2022: −24.59M USDOperating income, FY2023: −23.77M USDOperating income, FY2024: −20.16M USDOperating income, FY2025: −6.96M USDNet income, FY2021: −23.28M USDNet income, FY2022: −21M USDNet income, FY2023: −22.94M USDNet income, FY2024: −24.25M USDNet income, FY2025: −10.35M USDFY2021FY2022FY2023FY2024FY2025
Revenue FY2021 33K USD. Revenue FY2022 3.19M USD. Revenue FY2023 1.1M USD. Operating income FY2021 −24.74M USD. Operating income FY2022 −24.59M USD. Operating income FY2023 −23.77M USD. Operating income FY2024 −20.16M USD. Operating income FY2025 −6.96M USD. Net income FY2021 −23.28M USD. Net income FY2022 −21M USD. Net income FY2023 −22.94M USD. Net income FY2024 −24.25M USD. Net income FY2025 −10.35M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Revenue1.1M USD3.19M USD33K USD
Cost of goods sold456K USD972K USD941K USD16.68M USD14.58M USD
Gross profit−456K USD−972K USD155K USD−13.49M USD−14.55M USD
Research and development85K USD11.43M USD14.49M USD16.68M USD14.58M USD
Selling, general, and administrative6.88M USD7.76M USD9.43M USD11.1M USD10.19M USD
Operating expenses6.5M USD19.19M USD23.92M USD11.1M USD10.19M USD
Depreciation and amortization456K USD972K USD941K USD356K USD280K USD
Operating income−6.96M USD−20.16M USD−23.77M USD−24.59M USD−24.74M USD
Net income−10.35M USD−24.25M USD−22.94M USD−21M USD−23.28M USD

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
73%
8 beats, 2 misses, 1 met estimate
Average EPS surprise
-410.72%
11 comparable reports
Latest EPS result
-0.21
Estimate -1.32 · Beat by 84.06%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates-0.18-0.72-1.26-1.8Q2 '25BeatQ2 '25MissQ3 '25BeatQ4 '25BeatQ1 '26BeatQ2 '26BeatQ3 '26BeatQ4 '26Estimate
Q2 2025, reported Apr 4, 2025: actual -1, estimate -1.5, surprise +33.33%, Beat. Q2 2025, reported Apr 15, 2025: actual -1.68, estimate -1.5, surprise -12.00%, Miss. Q3 2025, reported Aug 14, 2025: actual -1.03, estimate -1.25, surprise +17.60%, Beat. Q4 2025, reported Nov 10, 2025: actual -0.4, estimate -1.06, surprise +62.09%, Beat. Q1 2026, reported Mar 31, 2026: actual -0.26, estimate -0.78, surprise +66.67%, Beat. Q2 2026, reported May 8, 2026: actual -0.3, estimate -1.32, surprise +77.23%, Beat. Q3 2026, reported Aug 13, 2026: actual -0.21, estimate -1.32, surprise +84.06%, Beat. Q4 2026, reported Nov 12, 2026: actual —, estimate -1.5, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates322K221.75K121.5K21.25KQ3 '24EstimateQ4 '24EstimateQ2 '25EstimateQ4 '25EstimateQ1 '26EstimateQ2 '26EstimateQ3 '26EstimateQ4 '26Estimate
Q3 2024, reported Aug 14, 2024: actual —, estimate 300K USD, surprise —, Comparison unavailable. Q4 2024, reported Nov 13, 2024: actual —, estimate 300K USD, surprise —, Comparison unavailable. Q2 2025, reported Apr 4, 2025: actual —, estimate 300K USD, surprise —, Comparison unavailable. Q4 2025, reported Nov 10, 2025: actual —, estimate 25K USD, surprise —, Comparison unavailable. Q1 2026, reported Mar 31, 2026: actual —, estimate 25K USD, surprise —, Comparison unavailable. Q2 2026, reported May 8, 2026: actual —, estimate 25K USD, surprise —, Comparison unavailable. Q3 2026, reported Aug 13, 2026: actual —, estimate 25K USD, surprise —, Comparison unavailable. Q4 2026, reported Nov 12, 2026: actual —, estimate 25K USD, surprise —, Comparison unavailable.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Rating distribution

8 ratings
Strong buy00%
Buy788%
Hold113%
Sell00%
Strong sell00%

Recent analyst actions

1 institution
Maxim GroupdowngradeBuyHold

MTNB news

Corporate actions

Corporate action history

Stock split

Effective Sep 3, 2024

1:50

MTNB peers

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