Neurocrine Biosciences, Inc. logo

Neurocrine Biosciences, Inc.

NBIX

NASDAQHealthcareBiotechnology

Previous close

$152.57

−$0.36 · -0.24%

Aug 21, 4:00 PM ET

NBIX company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Buy

Favorable setup — positive multi-factor alignment

Valuation

98

Deep Value

Momentum

65

Gaining

Sentiment

77

Bullish

Risk resilience

80

Low Risk

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Company profile

Company website

Neurocrine Biosciences, Inc. is a pharmaceutical firm dedicated to the creation, advancement, and commercialization of medicines addressing a spectrum of neurological, endocrine, and psychiatric conditions. Its current therapeutic pipeline and marketed products target disorders such as tardive dyskinesia, Parkinson's disease, endometriosis, and uterine fibroids, alongside numerous experimental compounds in various clinical stages. The company's primary commercial asset is INGREZZA, a VMAT2 inhibitor indicated for the management of tardive dyskinesia. Other available treatments include ONGENTYS, which serves as an auxiliary therapy for individuals with Parkinson's disease who are also receiving levodopa/DOPA decarboxylase inhibitors; ORILISSA, prescribed for the alleviation of moderate to severe pain linked with endometriosis in women; and ORIAHNN, an oral, non-surgical option for pre-menopausal women experiencing significant menstrual bleeding associated with uterine fibroids. Furthermore, Neurocrine is actively progressing a number of drug candidates through clinical development. These include NBI-921352 for treating pediatric patients and adult focal epilepsy; NBI-827104, designed to address rare pediatric epilepsy and essential tremor; NBI-1065845 for major depressive disorder; NBI-1065846 specifically for anhedonia within major depressive disorder; and NBI-118568 for the treatment of schizophrenia. The company also maintains strategic licensing and collaborative ventures with partners such as Heptares Therapeutics Limited, Takeda Pharmaceutical Company Limited, Idorsia Pharmaceuticals Ltd, Xenon Pharmaceuticals Inc., Voyager Therapeutics, Inc., BIAL Portela & Ca, S.A., Mitsubishi Tanabe Pharma Corporation, and AbbVie Inc. Neurocrine Biosciences, Inc. was founded in 1992 and operates from its headquarters in San Diego, California.

Industry
Biotechnology
Sector
Healthcare
Headquarters
US
CEO
Kyle W. Gano
Listed since
May 23, 1996
Employees
2,500

Market position

Day range

Current $152.57

52-week range

Current $152.57

Open
$153.2
Previous close
$152.93
Volume
1.23M
0.97× average
Average volume
1.26M
Average daily volume
Market cap
15.34B USD
Beta
0.39
Market reference 1
50-day average
$166.94
-8.61% below average
200-day average
$147.16
+3.67% above average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
13.81B USD
P/E (TTM)
21.64×
P/B (TTM)
4.17×
P/S (TTM)
4.55×
EV / EBITDA
20.72×
Earnings yield
3.39%
Free cash flow yield
5.31%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
97.97%
Operating margin
23.38%
Net margin
20.91%
Return on equity
14.71%
Return on assets
10.33%
Return on invested capital
10.80%

Financial health

Debt / equity
0.11×
Current ratio
3.39×

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends108%71%35%-1%Gross margin, FY2021: 98.74%Gross margin, FY2022: 98.44%Gross margin, FY2023: 97.90%Gross margin, FY2024: 98.56%Gross margin, FY2025: 98.18%Operating margin, FY2021: 9.04%Operating margin, FY2022: 16.73%Operating margin, FY2023: 13.30%Operating margin, FY2024: 24.22%Operating margin, FY2025: 21.64%Net margin, FY2021: 7.90%Net margin, FY2022: 10.38%Net margin, FY2023: 13.23%Net margin, FY2024: 14.49%Net margin, FY2025: 16.73%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2021 98.74%. Gross margin FY2022 98.44%. Gross margin FY2023 97.90%. Gross margin FY2024 98.56%. Gross margin FY2025 98.18%. Operating margin FY2021 9.04%. Operating margin FY2022 16.73%. Operating margin FY2023 13.30%. Operating margin FY2024 24.22%. Operating margin FY2025 21.64%. Net margin FY2021 7.90%. Net margin FY2022 10.38%. Net margin FY2023 13.23%. Net margin FY2024 14.49%. Net margin FY2025 16.73%.

Income trends

Revenue

2.86B USD+21.45%

Operating income

619.1M USD+8.52%

Net income

478.6M USD+40.23%
Income trends across reported periods3.14B USD2.03B USD920.87M USD−187.49M USDRevenue, FY2021: 1.13B USDRevenue, FY2022: 1.49B USDRevenue, FY2023: 1.89B USDRevenue, FY2024: 2.36B USDRevenue, FY2025: 2.86B USDOperating income, FY2021: 102.5M USDOperating income, FY2022: 249M USDOperating income, FY2023: 250.9M USDOperating income, FY2024: 570.5M USDOperating income, FY2025: 619.1M USDNet income, FY2021: 89.6M USDNet income, FY2022: 154.5M USDNet income, FY2023: 249.7M USDNet income, FY2024: 341.3M USDNet income, FY2025: 478.6M USDFY2021FY2022FY2023FY2024FY2025
Revenue FY2021 1.13B USD. Revenue FY2022 1.49B USD. Revenue FY2023 1.89B USD. Revenue FY2024 2.36B USD. Revenue FY2025 2.86B USD. Operating income FY2021 102.5M USD. Operating income FY2022 249M USD. Operating income FY2023 250.9M USD. Operating income FY2024 570.5M USD. Operating income FY2025 619.1M USD. Net income FY2021 89.6M USD. Net income FY2022 154.5M USD. Net income FY2023 249.7M USD. Net income FY2024 341.3M USD. Net income FY2025 478.6M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Revenue2.86B USD2.36B USD1.89B USD1.49B USD1.13B USD
Cost of goods sold52.1M USD34M USD39.7M USD23.2M USD14.3M USD
Gross profit2.81B USD2.32B USD1.85B USD1.47B USD1.12B USD
Research and development1.02B USD731.1M USD565M USD463.8M USD328.1M USD
Selling, general, and administrative1.16B USD1.01B USD887.6M USD752.7M USD583.3M USD
Operating expenses2.19B USD1.75B USD1.6B USD1.22B USD1.02B USD
Interest income90.3M USD91M USD11.2M USD
Interest expense126.6M USD4.6M USD7.1M USD25.8M USD
Depreciation and amortization30.1M USD27.1M USD21.3M USD15.6M USD10.9M USD
Operating income619.1M USD570.5M USD250.9M USD249M USD102.5M USD
Net income478.6M USD341.3M USD249.7M USD154.5M USD89.6M USD

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
45%
5 beats, 6 misses, 0 met estimates
Average EPS surprise
-11.77%
11 comparable reports
Latest EPS result
1.39
Estimate 1.65 · Miss by 15.76%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates2.791.880.980.07Q1 '25MissQ2 '25MissQ3 '25BeatQ4 '25BeatQ1 '26BeatQ2 '26BeatQ3 '26MissQ4 '26Estimate
Q1 2025, reported Feb 6, 2025: actual 1, estimate 1.62, surprise -38.27%, Miss. Q2 2025, reported May 5, 2025: actual 0.08, estimate 0.535, surprise -85.05%, Miss. Q3 2025, reported Jul 30, 2025: actual 1.06, estimate 0.98, surprise +8.16%, Beat. Q4 2025, reported Oct 28, 2025: actual 2.04, estimate 1.58, surprise +29.11%, Beat. Q1 2026, reported Feb 11, 2026: actual 1.88, estimate 1.8, surprise +4.44%, Beat. Q2 2026, reported May 5, 2026: actual 1.94, estimate 1.22, surprise +59.02%, Beat. Q3 2026, reported Jul 30, 2026: actual 1.39, estimate 1.65, surprise -15.76%, Miss. Q4 2026, reported Oct 27, 2026: actual —, estimate 2.59, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates1.08B895.79M706.85M517.91MQ1 '25MissQ2 '25BeatQ3 '25MissQ4 '25MissQ1 '26BeatQ2 '26BeatQ3 '26BeatQ4 '26Estimate
Q1 2025, reported Feb 6, 2025: actual 627.7M USD, estimate 629.44M USD, surprise -0.28%, Miss. Q2 2025, reported May 5, 2025: actual 572.6M USD, estimate 559.63M USD, surprise +2.32%, Beat. Q3 2025, reported Jul 30, 2025: actual 687.5M USD, estimate 746.41M USD, surprise -7.89%, Miss. Q4 2025, reported Oct 28, 2025: actual 794.9M USD, estimate 806.8M USD, surprise -1.48%, Miss. Q1 2026, reported Feb 11, 2026: actual 805.5M USD, estimate 790.5M USD, surprise +1.90%, Beat. Q2 2026, reported May 5, 2026: actual 814.5M USD, estimate 768.25M USD, surprise +6.02%, Beat. Q3 2026, reported Jul 30, 2026: actual 959M USD, estimate 891.16M USD, surprise +7.61%, Beat. Q4 2026, reported Oct 27, 2026: actual —, estimate 1.04B USD, surprise —, Comparison unavailable.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Rating distribution

37 ratings
Strong buy00%
Buy3286%
Hold514%
Sell00%
Strong sell00%

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