BeOne Medicines AG logo

BeOne Medicines AG

ONC

NASDAQHealthcareBiotechnology

Latest quote

$374.48

+$5.31 · +1.44%

Aug 21, 3:55 PM ET

ONC company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Buy

Favorable setup — positive multi-factor alignment

Valuation

78

Undervalued

Momentum

49

Neutral

Sentiment

65

Bullish

Risk resilience

70

Moderate Risk

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Company profile

Company website

BeOne Medicines AG, an oncology company, engages in discovering and developing various treatments for cancer patients in the United States, China, Europe, and internationally. The company’s commercial stage products include BRUKINSA, a small molecule inhibitor of Bruton’s Tyrosine Kinase (BTK) for the treatment of various blood cancers; TEVIMBRA, an anti-PD-1 antibody immunotherapy for the treatment of various solid tumor and blood cancers; SYLVANT for the treatment of adult patients with multicentric castleman disease; BAITUOWEI for patients with BC in premenopausal and perimenopausal women, and cancer; and PARTRUVIX for the treatment of various solid tumors. Its clinical stage products comprise Sonrotoclax BGB-11417, a small molecule Bcl-2 inhibitor; BGB-16673, a BTK targeting chimeric degradation activation compound active against wild type and mutant BTK; BG-60366, an EGFR-targeted CDAC; BG-89894 (SYH2039), a MAT2A Inhibitor; BGB-58067, an MTA-Cooperative PRMT5 Inhibitor; BG-T187 and BG-C0902, an anti-EGFRxMET trispecific antibody; BGB-26808, a HPK-1 Inhibitor; BGB-C354, an anti-B7H3 ADC; Zanidatamab, a bispecific HER2-targeted antibody; BG-C137, an anti-FGFR2b ADC; BGB-53038, a Pan-KRAS Inhibitor; BGB-B2033, an anti-GPC3x4-1BB bispecific antibody; BGB-B3227, an anti-MUC1xCD16A bispecific antibody; BG-C477, an anti-CEAADC; BGB-43395, a CDK4 Inhibitor; BG-68501, a CDK2 Inhibitor; BG-C9074, an anti-B7H4 ADC; BGB-21447, a Bcl-2 Inhibitor; and BGB-45035, an IRAK4-targeted CDAC. It also has various preclinical programs. The company has agreements Amgen, BMS, Bio-Thera, EUSA Pharma, Luye Pharmaceutical, and Novartis. The company was formerly known as BeiGene, Ltd. and changed its name to BeOne Medicines AG in May 2025. BeOne Medicines AG was founded in 2010 and is based in Basel, Switzerland.

Industry
Biotechnology
Sector
Healthcare
Headquarters
CH
CEO
John V. Oyler
Listed since
Feb 3, 2016
Employees
12,000

Market position

Volume
252.6K
0.8× average
Average volume
315.47K
Average daily volume
Market cap
40.02B USD
Beta
0.5
Market reference 1

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
30.59B USD
P/E (TTM)
27.35×
P/B (TTM)
11.48×
P/S (TTM)
6.95×
EV / EBITDA
49.59×
Earnings yield
0.87%
Free cash flow yield
2.84%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
87.82%
Operating margin
15.05%
Net margin
10.68%
Return on equity
6.58%
Return on assets
3.50%
Return on invested capital
4.74%

Financial health

Debt / equity
0.22×
Current ratio
3.41×

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends110%19%-73%-164%Gross margin, FY2021: 85.98%Gross margin, FY2022: 79.77%Gross margin, FY2023: 84.55%Gross margin, FY2024: 84.41%Gross margin, FY2025: 87.49%Operating margin, FY2021: -122.31%Operating margin, FY2022: -126.40%Operating margin, FY2023: -49.12%Operating margin, FY2024: -14.91%Operating margin, FY2025: 8.37%Net margin, FY2021: -123.93%Net margin, FY2022: -141.52%Net margin, FY2023: -35.86%Net margin, FY2024: -16.92%Net margin, FY2025: 5.37%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2021 85.98%. Gross margin FY2022 79.77%. Gross margin FY2023 84.55%. Gross margin FY2024 84.41%. Gross margin FY2025 87.49%. Operating margin FY2021 -122.31%. Operating margin FY2022 -126.40%. Operating margin FY2023 -49.12%. Operating margin FY2024 -14.91%. Operating margin FY2025 8.37%. Net margin FY2021 -123.93%. Net margin FY2022 -141.52%. Net margin FY2023 -35.86%. Net margin FY2024 -16.92%. Net margin FY2025 5.37%.

Income trends

Revenue

5.34B USD+40.23%

Operating income

447.14M USD+1.02B USD

Net income

286.93M USD+931.72M USD
Income trends across reported periods6.08B USD3.14B USD200.24M USD−2.74B USDRevenue, FY2021: 1.18B USDRevenue, FY2022: 1.42B USDRevenue, FY2023: 2.46B USDRevenue, FY2024: 3.81B USDRevenue, FY2025: 5.34B USDOperating income, FY2021: −1.44B USDOperating income, FY2022: −1.79B USDOperating income, FY2023: −1.21B USDOperating income, FY2024: −568.2M USDOperating income, FY2025: 447.14M USDNet income, FY2021: −1.46B USDNet income, FY2022: −2B USDNet income, FY2023: −881.71M USDNet income, FY2024: −644.79M USDNet income, FY2025: 286.93M USDFY2021FY2022FY2023FY2024FY2025
Revenue FY2021 1.18B USD. Revenue FY2022 1.42B USD. Revenue FY2023 2.46B USD. Revenue FY2024 3.81B USD. Revenue FY2025 5.34B USD. Operating income FY2021 −1.44B USD. Operating income FY2022 −1.79B USD. Operating income FY2023 −1.21B USD. Operating income FY2024 −568.2M USD. Operating income FY2025 447.14M USD. Net income FY2021 −1.46B USD. Net income FY2022 −2B USD. Net income FY2023 −881.71M USD. Net income FY2024 −644.79M USD. Net income FY2025 286.93M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Revenue5.34B USD3.81B USD2.46B USD1.42B USD1.18B USD
Cost of goods sold668.54M USD594.09M USD379.92M USD286.48M USD164.91M USD
Gross profit4.67B USD3.22B USD2.08B USD1.13B USD1.01B USD
Research and development2.15B USD1.95B USD1.78B USD1.64B USD1.46B USD
Selling, general, and administrative2.08B USD1.83B USD1.51B USD1.28B USD990.12M USD
Operating expenses4.23B USD3.78B USD3.29B USD2.92B USD2.45B USD
Interest income70.51M USD47.84M USD74.01M USD52.48M USD15.76M USD
Interest expense58.23M USD
Depreciation and amortization141.69M USD171.76M USD87.68M USD66.28M USD46.46M USD
Operating income447.14M USD−568.2M USD−1.21B USD−1.79B USD−1.44B USD
Net income286.93M USD−644.79M USD−881.71M USD−2B USD−1.46B USD

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
67%
6 beats, 3 misses, 0 met estimates
Average EPS surprise
+53.42%
9 comparable reports
Latest EPS result
2.05
Estimate 1.63 · Beat by 25.77%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates2.330.98-0.36-1.71Q1 '25MissQ2 '25BeatQ3 '25BeatQ4 '25BeatQ1 '26MissQ2 '26BeatQ3 '26BeatQ4 '26Estimate
Q1 2025, reported Feb 27, 2025: actual -1.43, estimate -0.88, surprise -62.50%, Miss. Q2 2025, reported May 7, 2025: actual 1.22, estimate -0.71, surprise +271.83%, Beat. Q3 2025, reported Aug 6, 2025: actual 0.84, estimate 0.48, surprise +75.00%, Beat. Q4 2025, reported Nov 6, 2025: actual 1.09, estimate 0.72, surprise +51.39%, Beat. Q1 2026, reported Feb 26, 2026: actual 0.58, estimate 1.6, surprise -63.75%, Miss. Q2 2026, reported May 6, 2026: actual 1.96, estimate 0.73, surprise +168.49%, Beat. Q3 2026, reported Aug 5, 2026: actual 2.05, estimate 1.63, surprise +25.77%, Beat. Q4 2026, reported Nov 5, 2026: actual —, estimate 1.9, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates1.82B1.54B1.25B969.07MQ1 '25BeatQ2 '25MissQ3 '25MissQ4 '25MissQ1 '26BeatQ2 '26BeatQ3 '26BeatQ4 '26Estimate
Q1 2025, reported Feb 27, 2025: actual 1.13B USD, estimate 1.04B USD, surprise +8.53%, Beat. Q2 2025, reported May 7, 2025: actual 1.12B USD, estimate 1.25B USD, surprise -10.36%, Miss. Q3 2025, reported Aug 6, 2025: actual 1.32B USD, estimate 1.44B USD, surprise -8.82%, Miss. Q4 2025, reported Nov 6, 2025: actual 1.41B USD, estimate 1.45B USD, surprise -2.72%, Miss. Q1 2026, reported Feb 26, 2026: actual 1.5B USD, estimate 1.47B USD, surprise +2.24%, Beat. Q2 2026, reported May 6, 2026: actual 1.51B USD, estimate 1.44B USD, surprise +5.35%, Beat. Q3 2026, reported Aug 5, 2026: actual 1.71B USD, estimate 1.62B USD, surprise +4.95%, Beat. Q4 2026, reported Nov 5, 2026: actual —, estimate 1.75B USD, surprise —, Comparison unavailable.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Rating distribution

14 ratings
Strong buy00%
Buy14100%
Hold00%
Sell00%
Strong sell00%

Recent analyst actions

12 institutions

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