
OPKO Health, Inc.
OPKNASDAQHealthcareMedical - Diagnostics & Research
Regular session
$1.495
+$0.015 · +1.01%
OPK company overview
Regular session · ET · Market data may be delayed.
GoAI snapshot
AI-powered factor overview
GoAI score
Sell
Trim exposure — unfavorable risk-reward
Valuation
42
Fair Value
Momentum
48
Neutral
Sentiment
41
Mixed
Risk resilience
52
Elevated Risk
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Company profile
Company websiteOPKO Health, Inc. operates as a healthcare enterprise with a dual focus on diagnostics and pharmaceuticals. Its operations span the United States, Ireland, Chile, Spain, Israel, Mexico, and other international markets. The company's Diagnostics division encompasses BioReference Laboratories, which delivers a comprehensive suite of laboratory testing services. These services are crucial for disease detection, diagnosis, evaluation, monitoring, and treatment, covering areas such as esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare. BioReference serves a diverse client base, including medical practices, clinics, hospitals, employers, and government entities. Additionally, this segment provides a cutting-edge diagnostic instrument system designed for immediate, point-of-care blood test results, alongside its specialized 4Kscore testing for prostate cancer. Within the Pharmaceutical segment, OPKO offers a range of therapeutic products and a robust development pipeline. Key offerings include Rayaldee, indicated for the management of secondary hyperparathyroidism in adults suffering from stage 3 or 4 chronic kidney disease and vitamin D insufficiency. The pipeline features OPK88004, an investigational orally administered selective androgen receptor modulator; OPK88003, a peptide administered once weekly currently in Phase IIb trials for the treatment of type 2 diabetes and obesity; and hGH-CTP, a once-weekly human growth hormone injection that has successfully completed Phase III clinical trials in collaboration with Pfizer, Inc. A core strategy for this segment involves the development and commercialization of proprietary, extended-release versions of existing therapeutic proteins. Furthermore, OPKO Health supplies specialty active pharmaceutical ingredients (APIs) and is involved in the development, manufacturing, marketing, and sale of pharmaceutical, nutraceutical, veterinary, and ophthalmic products. The company also commercializes food supplements and over-the-counter products, produces and sells items primarily within the generics market, and handles the import, marketing, distribution, and sales of pharmaceutical products across various therapeutic areas, including cardiovascular conditions, vaccines, antibiotics, gastro-intestinal ailments, and hormone-related treatments, among others. Its pharmaceutical operations are further bolstered by platforms situated in Ireland, Chile, Spain, and Mexico. Founded in 1991, OPKO Health, Inc. maintains its corporate headquarters in Miami, Florida.
- Industry
- Medical - Diagnostics & Research
- Sector
- Healthcare
- Headquarters
- US
- CEO
- Phillip Frost
- Listed since
- Nov 2, 1995
- Employees
- 2,275
Market position
Day range
Current $1.495
52-week range
Current $1.495
- Open
- $1.49
- Previous close
- $1.48
- Volume
- 780.3K
- 0.24× average
- Average volume
- 3.2M
- Average daily volume
- Market cap
- 1.12B USD
- Beta
- 1.49
- Market reference 1
- 50-day average
- $1.3754
- +8.70% above average
- 200-day average
- $1.2851
- +16.33% above average
Financials
Financial snapshot
Latest / TTMValuation & yield
- P/E (TTM)
- -15.69×
- P/B (TTM)
- 0.95×
- P/S (TTM)
- 1.9×
- Dividend yield
- 0.00%
Profitability & efficiency
- Gross margin
- 30.98%
- Operating margin
- -25.49%
- Net margin
- -12.40%
Financial health
- Debt / equity
- 0.33×
Financial statements
Margin trends
Profitability as a percentage of reported revenue.
Income trends
Revenue
Operating income
Net income
| Metric (USD) | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 |
|---|---|---|---|---|---|
| Revenue | 606.88M USD | 713.14M USD | 863.5M USD | 1B USD | 1.77B USD |
| Cost of goods sold | 478.83M USD | 402.11M USD | 545.37M USD | 715.98M USD | 1.19B USD |
| Gross profit | 128.05M USD | 311.03M USD | 318.13M USD | 288.22M USD | 581.52M USD |
| Research and development | 124.03M USD | 105.21M USD | 89.59M USD | 73.89M USD | 76.85M USD |
| Selling, general, and administrative | 223M USD | 304.22M USD | 300.56M USD | 372.67M USD | 468.86M USD |
| Operating expenses | 347.04M USD | 463.1M USD | 475.15M USD | 514.47M USD | 562.77M USD |
| Interest income | 14.81M USD | 8.43M USD | 3.98M USD | 1.98M USD | 28K USD |
| Interest expense | 108.46M USD | 47.47M USD | 13.51M USD | 12.06M USD | 18.88M USD |
| Depreciation and amortization | 91.63M USD | 98.18M USD | 105.3M USD | 108.66M USD | 78.72M USD |
| Operating income | −218.99M USD | −152.07M USD | −157.02M USD | −226.25M USD | 18.75M USD |
| Net income | −225.68M USD | −53.22M USD | −188.86M USD | −328.41M USD | −30.14M USD |
Company facts updated Aug 24, 2026.
Earnings
- EPS beat rate
- 55%
- 6 beats, 3 misses, 2 met estimates
- Average EPS surprise
- +50.31%
- 11 comparable reports
- Latest EPS result
- -0.01
- Estimate -0.08 · Beat by 87.50%
EPS: actual versus estimate
Recent quarterly results
Revenue: actual versus estimate
Recent quarterly results
Analyst ratings
Third-party consensus; not a GoAI recommendation.
Rating distribution
13 ratingsOPK peers
ETFs holding OPK
Funds reporting this stock among their holdings, ordered by reported position size.
iShares Russell 2000 ETFIWM15.18M0.02%81.62B USD0.19%$298.3-0.56%
Vanguard Morningstar Total Stock Market ETFVTI12.87M0.00%2.3T USD0.03%$376.73-0.40%
Vanguard Morningstar Small-Cap ETFVB9.14M0.00%183.4B USD0.03%$302.85-0.63%
Vanguard Extended Market ETFVXF6.5M0.01%93.7B USD0.05%$243.65-0.77%
iShares Russell 2000 Value ETFIWN5.63M0.04%14.66B USD0.24%$224.38-0.19%
iShares Biotechnology ETFIBB4.12M0.04%10.75B USD0.44%$211.46-0.98%
Schwab U.S. Small-Cap ETFSCHA2.99M0.01%23.1B USD0.03%$34.4201-1.19%
Vanguard Russell 2000 ETFVTWO2.98M0.02%17.4B USD0.06%$120.6-0.54%
iShares Russell 2000 ETFIWM- Market value
- 15.18M
- Weight
- 0.02%
- AUM
- 81.62B USD
- Expense ratio
- 0.19%
- Price / 1D
- $298.3-0.56%
Vanguard Morningstar Total Stock Market ETFVTI- Market value
- 12.87M
- Weight
- 0.00%
- AUM
- 2.3T USD
- Expense ratio
- 0.03%
- Price / 1D
- $376.73-0.40%
Vanguard Morningstar Small-Cap ETFVB- Market value
- 9.14M
- Weight
- 0.00%
- AUM
- 183.4B USD
- Expense ratio
- 0.03%
- Price / 1D
- $302.85-0.63%
Vanguard Extended Market ETFVXF- Market value
- 6.5M
- Weight
- 0.01%
- AUM
- 93.7B USD
- Expense ratio
- 0.05%
- Price / 1D
- $243.65-0.77%
iShares Russell 2000 Value ETFIWN- Market value
- 5.63M
- Weight
- 0.04%
- AUM
- 14.66B USD
- Expense ratio
- 0.24%
- Price / 1D
- $224.38-0.19%
iShares Biotechnology ETFIBB- Market value
- 4.12M
- Weight
- 0.04%
- AUM
- 10.75B USD
- Expense ratio
- 0.44%
- Price / 1D
- $211.46-0.98%
Schwab U.S. Small-Cap ETFSCHA- Market value
- 2.99M
- Weight
- 0.01%
- AUM
- 23.1B USD
- Expense ratio
- 0.03%
- Price / 1D
- $34.4201-1.19%
Vanguard Russell 2000 ETFVTWO- Market value
- 2.98M
- Weight
- 0.02%
- AUM
- 17.4B USD
- Expense ratio
- 0.06%
- Price / 1D
- $120.6-0.54%
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