Precigen, Inc. logo

Precigen, Inc.

PGEN

NASDAQHealthcareBiotechnology

Previous close

$7.20

−$0.24 · -3.23%

Aug 21, 4:00 PM ET

PGEN company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Sell

Trim exposure — unfavorable risk-reward

Valuation

2

Overpriced

Momentum

68

Gaining

Sentiment

63

Bullish

Risk resilience

53

Elevated Risk

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Company profile

Company website

Precigen, Inc. is an American company dedicated to the discovery and development of cutting-edge gene and cellular therapies. The company also offers disease-modifying treatments, genetically engineered swine for regenerative medicine, and advanced reproductive and embryo transfer technologies. Its extensive portfolio of proprietary platforms includes UltraVector, which leverages advanced DNA construction and computational modeling to engineer complex gene expression programs; mbIL15, a gene designed to enhance immune cell function; the non-viral Sleeping Beauty transposon/transposase system for genetic modification; and AttSite recombinases, tools for precise DNA recombination. Furthermore, Precigen utilizes its AdenoVerse platform, a library of engineered adenovectors for gene delivery and immunotherapy applications, alongside L. lactis, a food-grade bacterium. The company also provides RheoSwitch, an inducible gene switch system offering quantitative, dose-proportionate control over target protein expression's timing and amount; kill switches, designed to selectively eliminate cell therapies within the body; tissue-specific promoters for targeted gene expression; the UltraCAR-T platform for cancer treatment; and the ActoBiotics platform, which employs genetically modified bacteria to deliver proteins and peptides directly to mucosal sites. Precigen maintains strategic collaboration and license agreements with Alaunos Therapeutics, Inc., Ares Trading S.A., Oragenics, Inc., Castle Creek Biosciences, Inc., and Intrexon Energy Partners I and II, LLC. Established in 1998, Precigen, Inc., previously known as Intrexon Corporation, adopted its current name in January 2020 and is headquartered in Germantown, Maryland.

Industry
Biotechnology
Sector
Healthcare
Headquarters
US
CEO
Helen Sabzevari
Listed since
Aug 8, 2013
Employees
160

Market position

Day range

Current $7.20

52-week range

Current $7.20

Open
$7.50
Previous close
$7.44
Volume
4.41M
0.93× average
Average volume
4.76M
Average daily volume
Market cap
2.57B USD
Beta
1.01
Market reference 1
50-day average
$5.7788
+24.59% above average
200-day average
$4.4953
+60.17% above average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
1.34B USD
P/E (TTM)
-6.36×
P/B (TTM)
58.97×
P/S (TTM)
29.95×
EV / EBITDA
-5.51×
Earnings yield
-19.68%
Free cash flow yield
-7.05%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
89.56%
Operating margin
-46.08%
Net margin
-183.98%
Return on equity
-1198.61%
Return on assets
-160.03%
Return on invested capital
-88.50%

Financial health

Debt / equity
2.26×
Current ratio
3.09×
Altman Z-score
-8.62
Piotroski F-score
4 of 9

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends460%-958%-2377%-3795%Gross margin, FY2021: -276.24%Gross margin, FY2022: 76.44%Gross margin, FY2023: 1.70%Gross margin, FY2024: -8.71%Gross margin, FY2025: 37.05%Operating margin, FY2021: -644.48%Operating margin, FY2022: -281.42%Operating margin, FY2023: -1602.54%Operating margin, FY2024: -3440.23%Operating margin, FY2025: -1100.78%Net margin, FY2021: -646.01%Net margin, FY2022: 105.23%Net margin, FY2023: -1540.63%Net margin, FY2024: -3216.18%Net margin, FY2025: -2588.21%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2021 -276.24%. Gross margin FY2022 76.44%. Gross margin FY2023 1.70%. Gross margin FY2024 -8.71%. Gross margin FY2025 37.05%. Operating margin FY2021 -644.48%. Operating margin FY2022 -281.42%. Operating margin FY2023 -1602.54%. Operating margin FY2024 -3440.23%. Operating margin FY2025 -1100.78%. Net margin FY2021 -646.01%. Net margin FY2022 105.23%. Net margin FY2023 -1540.63%. Net margin FY2024 -3216.18%. Net margin FY2025 -2588.21%.

Income trends

Revenue

9.68M USD+146.73%

Operating income

−106.6M USD+21.05%

Net income

−250.64M USD-98.55%
Income trends across reported periods56.21M USD−55.37M USD−166.95M USD−278.54M USDRevenue, FY2021: 14.27M USDRevenue, FY2022: 26.91M USDRevenue, FY2023: 6.23M USDRevenue, FY2024: 3.93M USDRevenue, FY2025: 9.68M USDOperating income, FY2021: −91.95M USDOperating income, FY2022: −75.73M USDOperating income, FY2023: −99.76M USDOperating income, FY2024: −135.03M USDOperating income, FY2025: −106.6M USDNet income, FY2021: −92.17M USDNet income, FY2022: 28.32M USDNet income, FY2023: −95.9M USDNet income, FY2024: −126.24M USDNet income, FY2025: −250.64M USDFY2021FY2022FY2023FY2024FY2025
Revenue FY2021 14.27M USD. Revenue FY2022 26.91M USD. Revenue FY2023 6.23M USD. Revenue FY2024 3.93M USD. Revenue FY2025 9.68M USD. Operating income FY2021 −91.95M USD. Operating income FY2022 −75.73M USD. Operating income FY2023 −99.76M USD. Operating income FY2024 −135.03M USD. Operating income FY2025 −106.6M USD. Net income FY2021 −92.17M USD. Net income FY2022 28.32M USD. Net income FY2023 −95.9M USD. Net income FY2024 −126.24M USD. Net income FY2025 −250.64M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Revenue9.68M USD3.93M USD6.23M USD26.91M USD14.27M USD
Cost of goods sold6.1M USD4.27M USD6.12M USD6.34M USD53.68M USD
Gross profit3.59M USD−342K USD106K USD20.57M USD−39.41M USD
Research and development40.06M USD53.07M USD48.61M USD47.17M USD47.93M USD
Selling, general, and administrative70.13M USD41.29M USD40.42M USD48.01M USD
Operating expenses110.19M USD134.69M USD99.86M USD96.3M USD52.54M USD
Interest income3.22M USD1.42M USD3.24M USD133K USD171K USD
Interest expense3.87M USD6K USD468K USD6.77M USD18.76M USD
Depreciation and amortization3.2M USD4.53M USD6.67M USD10.77M USD13.76M USD
Operating income−106.6M USD−135.03M USD−99.76M USD−75.73M USD−91.95M USD
Net income−250.64M USD−126.24M USD−95.9M USD28.32M USD−92.17M USD

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
36%
4 beats, 6 misses, 1 met estimate
Average EPS surprise
-72.59%
11 comparable reports
Latest EPS result
0.05
Estimate -0.01 · Beat by 514.25%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates0.18-0.26-0.71-1.15Q1 '25BeatQ2 '25MissQ3 '25MissQ4 '25MissQ1 '26BeatQ2 '26BeatQ3 '26BeatQ4 '26Estimate
Q1 2025, reported Mar 19, 2025: actual -0.04, estimate -0.06, surprise +33.33%, Beat. Q2 2025, reported May 14, 2025: actual -0.18, estimate -0.08, surprise -125.00%, Miss. Q3 2025, reported Aug 12, 2025: actual -0.11, estimate -0.087, surprise -26.92%, Miss. Q4 2025, reported Nov 13, 2025: actual -1.06, estimate -0.08, surprise -1225.00%, Miss. Q1 2026, reported Mar 25, 2026: actual -0.066, estimate -0.1, surprise +33.60%, Beat. Q2 2026, reported May 13, 2026: actual -0.02, estimate -0.03, surprise +33.33%, Beat. Q3 2026, reported Aug 4, 2026: actual 0.05, estimate -0.012, surprise +514.25%, Beat. Q4 2026, reported Nov 12, 2026: actual —, estimate 0.09, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates74.71M49.95M25.19M425KQ1 '25MissQ2 '25BeatQ3 '25MissQ4 '25BeatQ1 '26MissQ2 '26BeatQ3 '26BeatQ4 '26Estimate
Q1 2025, reported Mar 19, 2025: actual 1.19M USD, estimate 3.03M USD, surprise -60.66%, Miss. Q2 2025, reported May 14, 2025: actual 1.34M USD, estimate 650K USD, surprise +106.31%, Beat. Q3 2025, reported Aug 12, 2025: actual 878K USD, estimate 952K USD, surprise -7.77%, Miss. Q4 2025, reported Nov 13, 2025: actual 2.92M USD, estimate 500K USD, surprise +484.40%, Beat. Q1 2026, reported Mar 25, 2026: actual 4.58M USD, estimate 8.42M USD, surprise -45.56%, Miss. Q2 2026, reported May 13, 2026: actual 23.25M USD, estimate 20.81M USD, surprise +11.75%, Beat. Q3 2026, reported Aug 4, 2026: actual 54.98M USD, estimate 27.98M USD, surprise +96.47%, Beat. Q4 2026, reported Nov 12, 2026: actual —, estimate 69.21M USD, surprise —, Comparison unavailable.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Analyst price target

Average target

$18.00

150.00% upside
Past 12 months12-month forecastHigh $18.00Average $18.00Low $18.00

Rating distribution

16 ratings
Strong buy00%
Buy1169%
Hold425%
Sell16%
Strong sell00%

Recent analyst actions

7 institutions
Cantor FitzgeraldmaintainOverweight
Citizens Capital MarketsmaintainMarket Outperform

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