
Personalis, Inc.
PSNLNASDAQHealthcareMedical - Diagnostics & Research
Previous close
$18.38
+$1.50 · +8.89%
PSNL company overview
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GoAI snapshot
AI-powered factor overview
GoAI score
Sell
Trim exposure — unfavorable risk-reward
Valuation
24
Expensive
Momentum
75
Gaining
Sentiment
51
Mixed
Risk resilience
44
Elevated Risk
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Company profile
Company websitePersonalis, Inc. operates globally as a specialized cancer genomics firm. The company delivers advanced sequencing and data analysis capabilities, primarily supporting the development of novel cancer treatments and facilitating extensive genetic research initiatives. Central to their offerings is the NeXT Platform, which enables detailed data analysis of tumors and their surrounding immune microenvironments, even from small tissue or plasma samples. This platform encompasses several specialized solutions: ImmunoID Next for tissue-based tumor profiling; NeXT Liquid Biopsy for plasma analysis; NeXT Personal, a specific liquid biopsy designed for individual patient tumor tracking; the NeXT Dx Test, a genomic cancer profiling tool that identifies composite biomarkers for treatment guidance; and the sophisticated NeXT SHERPA and NeXT NEOPS for predicting neoantigens. Additionally, Personalis offers the ACE platform, utilized for diverse clinical and therapeutic applications like neoantigen prediction, biomarker identification, and the selection of new drug targets. Their clientele includes biopharmaceutical companies, academic institutions, non-profit organizations, and government entities. The company has established significant partnerships with organizations such as Mayo Clinic, MapKure, LLC, SpringWorks Therapeutics, Inc., and Moores Cancer Center. Personalis, Inc. was founded in 2011 and is based in Menlo Park, California.
- Industry
- Medical - Diagnostics & Research
- Sector
- Healthcare
- Headquarters
- US
- CEO
- Christopher Hall
- Listed since
- Jun 20, 2019
- Employees
- 260
Market position
Day range
Current $18.38
52-week range
Current $18.38
- Open
- $16.655
- Previous close
- $16.88
- Volume
- 8M
- 2.2× average
- Average volume
- 3.63M
- Average daily volume
- Market cap
- 1.96B USD
- Beta
- 2.29
- Market reference 1
- 50-day average
- $13.1958
- +39.29% above average
- 200-day average
- $9.4277
- +94.96% above average
Financials
Financial snapshot
Latest / TTMValuation & yield
- Enterprise value
- 626.06M USD
- P/E (TTM)
- -16.86×
- P/B (TTM)
- 8.24×
- P/S (TTM)
- 28.16×
- EV / EBITDA
- -8.82×
- Earnings yield
- -11.44%
- Free cash flow yield
- -11.18%
- Dividend yield
- 0.00%
Profitability & efficiency
- Gross margin
- 12.69%
- Operating margin
- -164.07%
- Net margin
- -153.84%
- Return on equity
- -31.12%
- Return on assets
- -24.32%
- Return on invested capital
- -29.10%
Financial health
- Debt / equity
- 0.16×
- Current ratio
- 6.76×
- Altman Z-score
- 12.04
- Piotroski F-score
- 1 of 9
Financial statements
Margin trends
Profitability as a percentage of reported revenue.
Income trends
Revenue
Operating income
Net income
| Metric (USD) | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 |
|---|---|---|---|---|---|
| Revenue | 69.65M USD | 84.61M USD | 73.48M USD | 65.05M USD | 85.49M USD |
| Cost of goods sold | 53.87M USD | 57.79M USD | 55.27M USD | 51.7M USD | 53.84M USD |
| Gross profit | 15.78M USD | 26.83M USD | 18.21M USD | 13.35M USD | 31.66M USD |
| Research and development | 50.26M USD | 48.91M USD | 64.78M USD | 64.91M USD | 49.31M USD |
| Selling, general, and administrative | 53.57M USD | 46.19M USD | 49.73M USD | 63.97M USD | 47.7M USD |
| Operating expenses | 103.83M USD | 95.09M USD | 114.5M USD | 128.88M USD | 97.01M USD |
| Interest income | 7.16M USD | 5.51M USD | 5.9M USD | 2.4M USD | 367K USD |
| Interest expense | 205K USD | 24K USD | 110K USD | 201K USD | 184K USD |
| Depreciation and amortization | 10.05M USD | 10.94M USD | 11.3M USD | 8.43M USD | 6.01M USD |
| Operating income | −88.06M USD | −68.27M USD | −96.29M USD | −115.53M USD | −65.35M USD |
| Net income | −81.27M USD | −81.28M USD | −108.3M USD | −113.32M USD | −65.23M USD |
Company facts updated Aug 24, 2026.
Earnings
- EPS beat rate
- 73%
- 8 beats, 3 misses, 0 met estimates
- Average EPS surprise
- +3.44%
- 11 comparable reports
- Latest EPS result
- -0.3
- Estimate -0.26 · Miss by 13.93%
EPS: actual versus estimate
Recent quarterly results
Revenue: actual versus estimate
Recent quarterly results
Analyst ratings
Third-party consensus; not a GoAI recommendation.
Analyst price target
Average target
$14.63
20.40% downsideRating distribution
12 ratingsRecent analyst actions
PSNL peers
ETFs holding PSNL
Funds reporting this stock among their holdings, ordered by reported position size.
ARK Genomic Revolution ETFARKG128.83M6.21%1.56B USD0.75%$49.45+3.80%
iShares Russell 2000 ETFIWM29.52M0.04%81.62B USD0.19%$299.96+0.77%
Vanguard Morningstar Total Stock Market ETFVTI27.12M0.00%2.3T USD0.03%$378.24+0.44%
iShares Russell 2000 Value ETFIWN10.77M0.07%14.66B USD0.24%$224.81+0.45%
Vanguard Extended Market ETFVXF10.09M0.01%93.7B USD0.05%$245.53+0.82%
iShares Biotechnology ETFIBB7.87M0.07%10.75B USD0.44%$213.56+1.29%
Dimensional - US Small Cap ETFDFAS5.74M0.04%15.92B USD0.26%$83.02+0.73%
Vanguard Russell 2000 ETFVTWO4.82M0.03%17.4B USD0.06%$121.25+0.74%
ARK Genomic Revolution ETFARKG- Market value
- 128.83M
- Weight
- 6.21%
- AUM
- 1.56B USD
- Expense ratio
- 0.75%
- Price / 1D
- $49.45+3.80%
iShares Russell 2000 ETFIWM- Market value
- 29.52M
- Weight
- 0.04%
- AUM
- 81.62B USD
- Expense ratio
- 0.19%
- Price / 1D
- $299.96+0.77%
Vanguard Morningstar Total Stock Market ETFVTI- Market value
- 27.12M
- Weight
- 0.00%
- AUM
- 2.3T USD
- Expense ratio
- 0.03%
- Price / 1D
- $378.24+0.44%
iShares Russell 2000 Value ETFIWN- Market value
- 10.77M
- Weight
- 0.07%
- AUM
- 14.66B USD
- Expense ratio
- 0.24%
- Price / 1D
- $224.81+0.45%
Vanguard Extended Market ETFVXF- Market value
- 10.09M
- Weight
- 0.01%
- AUM
- 93.7B USD
- Expense ratio
- 0.05%
- Price / 1D
- $245.53+0.82%
iShares Biotechnology ETFIBB- Market value
- 7.87M
- Weight
- 0.07%
- AUM
- 10.75B USD
- Expense ratio
- 0.44%
- Price / 1D
- $213.56+1.29%
Dimensional - US Small Cap ETFDFAS- Market value
- 5.74M
- Weight
- 0.04%
- AUM
- 15.92B USD
- Expense ratio
- 0.26%
- Price / 1D
- $83.02+0.73%
Vanguard Russell 2000 ETFVTWO- Market value
- 4.82M
- Weight
- 0.03%
- AUM
- 17.4B USD
- Expense ratio
- 0.06%
- Price / 1D
- $121.25+0.74%
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