TransCode Therapeutics, Inc. logo

TransCode Therapeutics, Inc.

RNAZ

NASDAQHealthcareBiotechnology

Previous close

$2.87

−$0.10 · -3.37%

Aug 21, 4:00 PM ET

Pre-market

$2.972

+$0.102 · +3.55%

Aug 24, 7:48 AM ET

RNAZ company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Sell

Trim exposure — unfavorable risk-reward

Valuation

44

Fair Value

Momentum

55

Neutral

Sentiment

54

Mixed

Risk resilience

26

High Risk

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Company profile

Company website

TransCode Therapeutics, Inc. is a biopharmaceutical firm dedicated to pioneering and marketing therapeutic agents and diagnostic tools specifically aimed at combating and detecting metastatic disease. Central to its pipeline is TTX-MC138, a lead therapeutic compound currently undergoing preclinical evaluation for its potential in treating advanced, spreading cancers. Beyond its primary candidate, the company's preclinical portfolio also features TTX-siPDL1, an siRNA designed to modulate programmed death-ligand 1, and TTX-siLIN28B, another siRNA that inhibits the RNA-binding protein LIN28B. TransCode also pursues several cancer-agnostic initiatives. These encompass TTX-RIGA, an RNA-based agent engineered to stimulate the RIG-I immune pathway within the tumor's immediate surroundings; TTX-CRISPR, a gene-editing platform utilizing CRISPR/Cas9 technology to correct or eradicate oncogenic genes within cancer cells; and TTX-mRNA, an innovative mRNA platform dedicated to creating cancer vaccines that incite powerful cytotoxic immune reactions against malignant cells. Established in 2016, TransCode Therapeutics is headquartered in Boston, Massachusetts.

Industry
Biotechnology
Sector
Healthcare
Headquarters
US
CEO
Philippe Calais
Listed since
Jul 8, 2021
Employees
12

Market position

Day range

Current $2.87

52-week range

Current $2.87

Open
$2.94
Previous close
$2.97
Volume
42.18K
0.87× average
Average volume
48.33K
Average daily volume
Market cap
3.04M USD
Beta
1.24
Market reference 1
50-day average
$5.7415
-50.01% below average
200-day average
$7.7843
-63.13% below average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
-13.1M USD
P/E (TTM)
-0.06×
P/B (TTM)
0.02×
P/S (TTM)
EV / EBITDA
0.38×
Earnings yield
-735.79%
Free cash flow yield
-414.43%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
0.00%
Operating margin
0.00%
Net margin
0.00%
Return on equity
-335.36%
Return on assets
-21.34%
Return on invested capital
-17.61%

Financial health

Debt / equity
4.72×
Current ratio
6.29×
Altman Z-score
-44.88
Piotroski F-score
0 of 9

Financial statements

Income trends

Operating income

−27.98M USD-78.66%

Net income

−34.66M USD-106.87%
Income trends across reported periods−3.3M USD−14.7M USD−26.11M USD−37.51M USDOperating income, FY2021: −6.15M USDOperating income, FY2022: −18.67M USDOperating income, FY2023: −19.42M USDOperating income, FY2024: −15.66M USDOperating income, FY2025: −27.98M USDNet income, FY2021: −6.84M USDNet income, FY2022: −17.56M USDNet income, FY2023: −18.55M USDNet income, FY2024: −16.75M USDNet income, FY2025: −34.66M USDFY2021FY2022FY2023FY2024FY2025
Operating income FY2021 −6.15M USD. Operating income FY2022 −18.67M USD. Operating income FY2023 −19.42M USD. Operating income FY2024 −15.66M USD. Operating income FY2025 −27.98M USD. Net income FY2021 −6.84M USD. Net income FY2022 −17.56M USD. Net income FY2023 −18.55M USD. Net income FY2024 −16.75M USD. Net income FY2025 −34.66M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Cost of goods sold534.86K USD516.75K USD98.61K USD42.47K USD
Gross profit−534.86K USD−516.75K USD−98.61K USD−42.47K USD
Research and development13.42M USD9.62M USD12.26M USD10.23M USD2.75M USD
Selling, general, and administrative5.77M USD5.51M USD6.64M USD8.33M USD3.35M USD
Operating expenses27.98M USD15.13M USD18.9M USD18.57M USD6.11M USD
Interest income79.2K USD684 USD5.29K USD20.41K USD664 USD
Interest expense6.62K USD26.81K USD55.9K USD17.56M USD95.07K USD
Depreciation and amortization114.18K USD534.86K USD516.75K USD98.61K USD42.47K USD
Operating income−27.98M USD−15.66M USD−19.42M USD−18.67M USD−6.15M USD
Net income−34.66M USD−16.75M USD−18.55M USD−17.56M USD−6.84M USD

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
44%
4 beats, 5 misses, 0 met estimates
Average EPS surprise
-404.91%
9 comparable reports
Latest EPS result
-7.17

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates-1.7-164.07-326.45-488.82Q4 '24BeatQ2 '25MissQ2 '25MissQ3 '25BeatQ4 '25BeatQ2 '26MissQ2 '26No estimateQ3 '26No estimate
Q4 2024, reported Nov 14, 2024: actual -147.91, estimate -452.76, surprise +67.33%, Beat. Q2 2025, reported Apr 7, 2025: actual -8.5, estimate -3.21, surprise -164.80%, Miss. Q2 2025, reported May 21, 2025: actual -70.28, estimate -2, surprise -3414.00%, Miss. Q3 2025, reported Aug 14, 2025: actual -4.94, estimate -8.68, surprise +43.09%, Beat. Q4 2025, reported Nov 14, 2025: actual -5.49, estimate -9.24, surprise +40.58%, Beat. Q2 2026, reported Apr 15, 2026: actual -18.58, estimate -10.08, surprise -84.33%, Miss. Q2 2026, reported May 15, 2026: actual -21.28, estimate —, surprise —, Comparison unavailable. Q3 2026, reported Aug 14, 2026: actual -7.17, estimate —, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates324K308K292K276KQ4 '24EstimateQ2 '25Estimate
Q4 2024, reported Nov 14, 2024: actual —, estimate 300K USD, surprise —, Comparison unavailable. Q2 2025, reported Apr 7, 2025: actual —, estimate 300K USD, surprise —, Comparison unavailable.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Recent analyst actions

1 institution

RNAZ news

Corporate actions

Corporate action history

Stock split

Effective May 15, 2025

1:28

Stock split

Effective Dec 4, 2024

1:33

Stock split

Effective Jan 16, 2024

1:40

Stock split

Effective May 23, 2023

1:20

RNAZ peers

ETFs holding RNAZ

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