Sana Biotechnology, Inc. logo

Sana Biotechnology, Inc.

SANA

NASDAQHealthcareBiotechnology

Previous close

$3.91

+$0.17 · +4.55%

Aug 21, 4:00 PM ET

Pre-market

$3.86

−$0.05 · -1.28%

Aug 24, 5:13 AM ET

SANA company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Sell

Trim exposure — unfavorable risk-reward

Valuation

27

Expensive

Momentum

51

Neutral

Sentiment

54

Mixed

Risk resilience

29

High Risk

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Company profile

Company website

Sana Biotechnology, Inc. is a biotechnology firm focused on creating treatments using engineered cells. The company develops advanced ex vivo and in vivo cell engineering platforms to address a range of conditions with significant unmet medical needs, including various cancers, diabetes, central nervous system disorders, cardiovascular diseases, and genetic illnesses. Its portfolio of drug candidates includes SG295 and SG242, which are designed to target CD19+ cancer cells involved in non-Hodgkin Lymphoma, chronic lymphocytic leukemia, and acute lymphoblastic leukemia. For multiple myeloma, Sana is progressing SG221, SG239, and SC255. Other pipeline assets include SG328 for ornithine transcarbamylase deficiency, and SG418 for sickle cell disease and beta-thalassemia. Additionally, the company is advancing SC291, a CD19 allogeneic T cell therapy, SC451 for type I diabetes mellitus, and SC379 for secondary progressive multiple sclerosis, Pelizaeus-Merzbacher disease, and Huntington's disease. Founded in 2018 as FD Therapeutics, Inc., the company adopted its current name, Sana Biotechnology, Inc., in September 2018 and is based in Seattle, Washington.

Industry
Biotechnology
Sector
Healthcare
Headquarters
US
CEO
Steven D. Harr
Listed since
Feb 4, 2021
Employees
142

Market position

Day range

Current $3.91

52-week range

Current $3.91

Open
$3.79
Previous close
$3.74
Volume
2.93M
0.86× average
Average volume
3.42M
Average daily volume
Market cap
1.09B USD
Beta
2.1
Market reference 1
50-day average
$3.4366
+13.78% above average
200-day average
$3.7033
+5.58% above average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
1.04B USD
P/E (TTM)
-5.14×
P/B (TTM)
7.48×
P/S (TTM)
EV / EBITDA
-4.48×
Earnings yield
-23.69%
Free cash flow yield
-14.05%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
0.00%
Operating margin
0.00%
Net margin
0.00%
Return on equity
-151.77%
Return on assets
-58.57%
Return on invested capital
-54.08%

Financial health

Debt / equity
0.48×
Current ratio
1.89×
Altman Z-score
-5.49
Piotroski F-score
1 of 9

Financial statements

Income trends

Operating income

−190.96M USD+29.98%

Net income

−244.17M USD+8.47%
Income trends across reported periods−174.36M USD−240.74M USD−307.12M USD−373.5M USDOperating income, FY2021: −356.91M USDOperating income, FY2022: −272.56M USDOperating income, FY2023: −293.14M USDOperating income, FY2024: −272.72M USDOperating income, FY2025: −190.96M USDNet income, FY2021: −355.93M USDNet income, FY2022: −269.48M USDNet income, FY2023: −283.26M USDNet income, FY2024: −266.76M USDNet income, FY2025: −244.17M USDFY2021FY2022FY2023FY2024FY2025
Operating income FY2021 −356.91M USD. Operating income FY2022 −272.56M USD. Operating income FY2023 −293.14M USD. Operating income FY2024 −272.72M USD. Operating income FY2025 −190.96M USD. Net income FY2021 −355.93M USD. Net income FY2022 −269.48M USD. Net income FY2023 −283.26M USD. Net income FY2024 −266.76M USD. Net income FY2025 −244.17M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Cost of goods sold12.75M USD
Gross profit−12.75M USD
Research and development131.98M USD208.68M USD219.84M USD201M USD306.5M USD
Selling, general, and administrative44.3M USD64.04M USD73.3M USD71.56M USD50.41M USD
Operating expenses178.21M USD272.72M USD293.14M USD272.56M USD356.91M USD
Interest income3.85M USD10.47M USD9.94M USD3.76M USD676K USD
Depreciation and amortization12.75M USD17.39M USD24.56M USD15.63M USD11.07M USD
Operating income−190.96M USD−272.72M USD−293.14M USD−272.56M USD−356.91M USD
Net income−244.17M USD−266.76M USD−283.26M USD−269.48M USD−355.93M USD

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
55%
6 beats, 4 misses, 1 met estimate
Average EPS surprise
-12.04%
11 comparable reports
Latest EPS result
-0.22
Estimate -0.15 · Miss by 49.76%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates-0.11-0.22-0.32-0.43Q1 '25BeatQ2 '25BeatQ3 '25MissQ4 '25BeatQ1 '26MissQ2 '26BeatQ3 '26MissQ4 '26Estimate
Q1 2025, reported Mar 17, 2025: actual -0.23, estimate -0.25, surprise +8.00%, Beat. Q2 2025, reported May 8, 2025: actual -0.2, estimate -0.22, surprise +9.09%, Beat. Q3 2025, reported Aug 11, 2025: actual -0.39, estimate -0.2, surprise -95.00%, Miss. Q4 2025, reported Nov 6, 2025: actual -0.15, estimate -0.18, surprise +16.67%, Beat. Q1 2026, reported Mar 3, 2026: actual -0.16, estimate -0.13, surprise -23.08%, Miss. Q2 2026, reported May 11, 2026: actual -0.14, estimate -0.15, surprise +6.67%, Beat. Q3 2026, reported Aug 11, 2026: actual -0.22, estimate -0.147, surprise -49.76%, Miss. Q4 2026, reported Nov 5, 2026: actual —, estimate -0.16, surprise —, Comparison unavailable.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Analyst price target

Average target

$8.67

121.74% upside
Past 12 months12-month forecast

Price history unavailable

High $12.00Average $8.67Low $7.00

Recent analyst actions

8 institutions
CitizensmaintainMarket Outperform
Citizens Capital MarketsupgradeMarket PerformMarket Outperform
TD CowenupgradeHoldBuy
CitigroupmaintainBuy

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