Shuttle Pharmaceuticals Holdings, Inc. logo

Shuttle Pharmaceuticals Holdings, Inc.

SHPH

NASDAQHealthcareDrug Manufacturers - Specialty & Generic

Previous close

$3.76

+$0.05 · +1.35%

Aug 21, 4:00 PM ET

SHPH company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Sell

Trim exposure — unfavorable risk-reward

Valuation

25

Expensive

Momentum

17

Strong Down

Sentiment

53

Mixed

Risk resilience

29

High Risk

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Company profile

Company website

Shuttle Pharmaceuticals Holdings, Inc., in conjunction with its subsidiary Shuttle Pharmaceuticals, Inc., is committed to the identification, advancement, and commercialization of pharmaceutical agents crafted to heighten the susceptibility of cancerous cells to radiation therapy. Its current portfolio of clinical-phase treatments features Ropidoxuridine, an orally administered halogenated pyrimidine, which is intended for individuals afflicted with brain tumors and soft tissue sarcomas. Additionally, the company is progressing Doranidazole, an injectable compound designed to make oxygen-deprived tumor cells more responsive to radiation, targeting malignancies of the pancreas, lungs, and liver. This enterprise was established in 2012 and maintains its principal operations in Rockville, Maryland.

Industry
Drug Manufacturers - Specialty & Generic
Sector
Healthcare
Headquarters
US
CEO
Christopher Robert Cooper
Listed since
Aug 31, 2022
Employees
2

Market position

Day range

Current $3.76

52-week range

Current $3.76

Open
$3.74
Previous close
$3.71
Volume
10.43K
0.01× average
Average volume
2.07M
Average daily volume
Market cap
2.2M USD
Beta
1.22
Market reference 1
50-day average
$3.6333
+3.49% above average
200-day average
$10.5965
-64.52% below average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
2.85M USD
P/E (TTM)
-0.06×
P/B (TTM)
0.57×
P/S (TTM)
EV / EBITDA
-0.25×
Earnings yield
-397.58%
Free cash flow yield
-321.60%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
0.00%
Operating margin
0.00%
Net margin
0.00%
Return on equity
-519.94%
Return on assets
-111.89%
Return on invested capital
-460.77%

Financial health

Debt / equity
0.06×
Current ratio
0.06×

Financial statements

Income trends

Operating income

−11.92M USD-54.84%

Net income

−11.72M USD-28.18%
Income trends across reported periods−75.67K USD−4.38M USD−8.69M USD−12.99M USDOperating income, FY2021: −1.74M USDOperating income, FY2022: −2.34M USDOperating income, FY2023: −5.89M USDOperating income, FY2024: −7.7M USDOperating income, FY2025: −11.92M USDNet income, FY2021: −1.15M USDNet income, FY2022: −5M USDNet income, FY2023: −6.59M USDNet income, FY2024: −9.14M USDNet income, FY2025: −11.72M USDFY2021FY2022FY2023FY2024FY2025
Operating income FY2021 −1.74M USD. Operating income FY2022 −2.34M USD. Operating income FY2023 −5.89M USD. Operating income FY2024 −7.7M USD. Operating income FY2025 −11.92M USD. Net income FY2021 −1.15M USD. Net income FY2022 −5M USD. Net income FY2023 −6.59M USD. Net income FY2024 −9.14M USD. Net income FY2025 −11.72M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Cost of goods sold5.97K USD60.83K USD
Gross profit−5.97K USD−60.83K USD
Research and development4.05M USD3.62M USD3.52M USD1.05M USD1.02M USD
Selling, general, and administrative7.86M USD4.08M USD2.38M USD1.29M USD721.18K USD
Operating expenses11.92M USD7.7M USD5.89M USD2.34M USD1.68M USD
Interest income1.09K USD38.14K USD79.12K USD
Interest expense70.83K USD1.36M USD2.6M USD670.61K USD50.79K USD
Depreciation and amortization290.11K USD5.46K USD6.81K USD5.97K USD60.83K USD
Operating income−11.92M USD−7.7M USD−5.89M USD−2.34M USD−1.74M USD
Net income−11.72M USD−9.14M USD−6.59M USD−5M USD−1.15M USD

Company facts updated Aug 24, 2026.

Earnings

Latest EPS result
-4.3

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Estimates unavailable
Quarterly EPS actual values compared with estimates-0.68-14.74-28.8-42.87Q3 '24Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q2 '26Q2 '26
Q3 2024, reported Sep 3, 2024: actual -24, estimate —, surprise —, Comparison unavailable. Q4 2024, reported Nov 13, 2024: actual -39.75, estimate —, surprise —, Comparison unavailable. Q1 2025, reported Mar 20, 2025: actual -0.8, estimate —, surprise —, Comparison unavailable. Q2 2025, reported May 8, 2025: actual -7.5, estimate —, surprise —, Comparison unavailable. Q3 2025, reported Aug 12, 2025: actual -3.29, estimate —, surprise —, Comparison unavailable. Q4 2025, reported Nov 13, 2025: actual -1.05, estimate —, surprise —, Comparison unavailable. Q2 2026, reported Apr 1, 2026: actual -12.9, estimate —, surprise —, Comparison unavailable. Q2 2026, reported May 15, 2026: actual -4.3, estimate —, surprise —, Comparison unavailable.

Corporate actions

Corporate action history

Stock split

Effective Jun 11, 2026

1:10

Stock split

Effective Jun 16, 2025

1:25

Stock split

Effective Aug 13, 2024

1:8

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