Silexion Therapeutics Ltd. logo

Silexion Therapeutics Ltd.

SLXN

NASDAQHealthcareBiotechnology

Previous close

$0.3941

−$0.0049 · -1.23%

Aug 21, 4:00 PM ET

SLXN company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Sell

Trim exposure — unfavorable risk-reward

Valuation

43

Fair Value

Momentum

17

Strong Down

Sentiment

53

Mixed

Risk resilience

37

High Risk

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Company profile

Company website

Silexion Therapeutics LTD is a biopharmaceutical company specializing in the discovery and advancement of RNA interference (RNAi)-based cancer therapies and their associated delivery systems, with a focus on treating aggressive solid tumors. The company's strategy for addressing these tumors relies on its proprietary LODER delivery platform. Its product pipeline features several key candidates: SiG12D-LODER, which has progressed through both preclinical studies and an open-label Phase I clinical trial for pancreatic cancer; Prostate-LODER, currently undergoing preclinical evaluation for prostate cancer; and GBM-LODER, also in preclinical development, targeting Glioblastoma Multiforme, a highly malignant primary brain tumor. Founded in 2008, Silexion Therapeutics is headquartered in Jerusalem, Israel.

Industry
Biotechnology
Sector
Healthcare
Headquarters
IL
CEO
Ilan Hadar
Listed since
Aug 16, 2024
Employees
14

Market position

Day range

Current $0.3941

52-week range

Current $0.3941

Open
$0.389
Previous close
$0.399
Volume
226.98K
0.4× average
Average volume
562.54K
Average daily volume
Market cap
165.13K USD
Beta
-0.25
Market reference 1
50-day average
$2.1083
-81.31% below average
200-day average
$12.8391
-96.93% below average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
-2.97M USD
P/E (TTM)
-0.01×
P/B (TTM)
6.16×
P/S (TTM)
EV / EBITDA
0.25×
Earnings yield
-466.65%
Free cash flow yield
-424.19%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
0.00%
Operating margin
0.00%
Net margin
0.00%
Return on equity
-457.63%
Return on assets
-165.10%
Return on invested capital
250.74%

Financial health

Debt / equity
32.05×
Current ratio
2.41×
Altman Z-score
-31.25
Piotroski F-score
1 of 9

Financial statements

Income trends

Operating income

11.63M USD+24.2M USD

Net income

−11.91M USD+27.56%
Income trends across reported periods14.44M USD3.21M USD−8.02M USD−19.25M USDOperating income, FY2021: −943.93K USDOperating income, FY2022: −3.86M USDOperating income, FY2023: −4.68M USDOperating income, FY2024: −12.57M USDOperating income, FY2025: 11.63M USDNet income, FY2021: −755.22K USDNet income, FY2022: −3.22M USDNet income, FY2023: −4.94M USDNet income, FY2024: −16.44M USDNet income, FY2025: −11.91M USDFY2021FY2022FY2023FY2024FY2025
Operating income FY2021 −943.93K USD. Operating income FY2022 −3.86M USD. Operating income FY2023 −4.68M USD. Operating income FY2024 −12.57M USD. Operating income FY2025 11.63M USD. Net income FY2021 −755.22K USD. Net income FY2022 −3.22M USD. Net income FY2023 −4.94M USD. Net income FY2024 −16.44M USD. Net income FY2025 −11.91M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Research and development7.14M USD5.82M USD3.71M USD3.23M USD
Selling, general, and administrative4.48M USD6.73M USD928K USD577K USD943.93K USD
Operating expenses−11.63M USD12.57M USD4.68M USD3.86M USD943.93K USD
Interest income142K USD1K USD153K USD114K USD6.37K USD
Interest expense13K USD52K USD9K USD85K USD
Depreciation and amortization14K USD25K USD45K USD57K USD
Operating income11.63M USD−12.57M USD−4.68M USD−3.86M USD−943.93K USD
Net income−11.91M USD−16.44M USD−4.94M USD−3.22M USD−755.22K USD

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
50%
4 beats, 4 misses, 0 met estimates
Average EPS surprise
-230.94%
8 comparable reports
Latest EPS result
-5.17
Estimate -21.2 · Beat by 75.61%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates-0.99-53.55-106.11-158.67Q1 '25BeatQ2 '25MissQ3 '25MissQ4 '25BeatQ1 '26MissQ2 '26BeatQ3 '26BeatQ4 '26Estimate
Q1 2025, reported Mar 18, 2025: actual -115.5, estimate -147, surprise +21.43%, Beat. Q2 2025, reported May 13, 2025: actual -38.98, estimate -33, surprise -18.12%, Miss. Q3 2025, reported Aug 12, 2025: actual -43.2, estimate -31.5, surprise -37.14%, Miss. Q4 2025, reported Nov 12, 2025: actual -28.8, estimate -34, surprise +15.29%, Beat. Q1 2026, reported Mar 17, 2026: actual -23.85, estimate -1.17, surprise -1938.46%, Miss. Q2 2026, reported May 12, 2026: actual -8.5, estimate -12.9, surprise +34.11%, Beat. Q3 2026, reported Aug 14, 2026: actual -5.17, estimate -21.2, surprise +75.61%, Beat. Q4 2026, reported Nov 11, 2026: actual —, estimate -9.1, surprise —, Comparison unavailable.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Recent analyst actions

1 institution
Maxim GroupmaintainBuy

SLXN news

Corporate actions

Corporate action history

Stock split

Effective May 29, 2026

1:10

Stock split

Effective Jul 29, 2025

1:15

Stock split

Effective Nov 29, 2024

1:9

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