Tonix Pharmaceuticals Holding Corp. logo

Tonix Pharmaceuticals Holding Corp.

TNXP

NASDAQHealthcareBiotechnology

Previous close

$12.55

+$0.16 · +1.29%

Aug 21, 4:00 PM ET

TNXP company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Hold

Wait — insufficient conviction to act

Valuation

88

Deep Value

Momentum

34

Weakening

Sentiment

73

Bullish

Risk resilience

26

High Risk

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Company profile

Company website

Tonix Pharmaceuticals Holding Corp. is a biopharmaceutical firm primarily operating in the clinical development stage. Its overarching mission involves the discovery, acquisition, advancement, and commercialization of novel therapeutic agents and diagnostic tools, all aimed at combating human illnesses and easing patient discomfort. The company boasts a comprehensive pipeline of potential treatments spanning several key medical fields: immunology, rare conditions, infectious diseases, and central nervous system (CNS) disorders. In the realm of immunology, Tonix is progressing with biologics designed to address organ transplant rejection, various autoimmune diseases, and certain forms of cancer. A prominent candidate here is TNX-1500, a humanized monoclonal antibody targeting CD40-ligand, which is being investigated for its utility in preventing both allograft and xenograft rejection, as well as in treating autoimmune disorders. Its rare disease initiatives include TNX-2900, a specific treatment candidate for Prader-Willi syndrome. The infectious disease segment features a diverse array of programs: TNX-801, a vaccine designed to offer protection against smallpox and monkeypox. TNX-1840 and TNX-1850, which are live virus vaccines based on the company's recombinant pox vaccine (RPV) platform, targeting COVID-19. TNX-3500, a small molecule antiviral drug for the treatment of acute COVID-19. TNX-102 SL, a small molecule medication under investigation for Long COVID, a persistent post-acute COVID-19 condition. Finally, the CNS portfolio encompasses both small molecules and biologics intended to manage pain, neurological conditions, psychiatric ailments, and addiction. Notably, TNX-102 SL is also in mid-Phase 3 development for alleviating fibromyalgia symptoms. Other CNS candidates include TNX-1900, which is being developed to prevent migraine headaches, and TNX-1300, a biologic aimed at treating cocaine intoxication. The company was established in 2007 and maintains its headquarters in Chatham, New Jersey.

Industry
Biotechnology
Sector
Healthcare
Headquarters
US
CEO
Seth Lederman
Listed since
May 10, 2012
Employees
142

Market position

Day range

Current $12.55

52-week range

Current $12.55

Open
$12.68
Previous close
$12.39
Volume
369.68K
0.75× average
Average volume
492.27K
Average daily volume
Market cap
200.06M USD
Beta
1.69
Market reference 1
50-day average
$11.78
+6.54% above average
200-day average
$14.2907
-12.18% below average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
-73.38M USD
P/E (TTM)
-0.95×
P/B (TTM)
0.94×
P/S (TTM)
6.87×
EV / EBITDA
0.6×
Earnings yield
-93.29%
Free cash flow yield
-77.63%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
80.25%
Operating margin
-568.43%
Net margin
-548.64%
Return on equity
-50.59%
Return on assets
-44.75%
Return on invested capital
-51.00%

Financial health

Debt / equity
0.01×
Current ratio
7.42×

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends195%-430%-1055%-1680%Gross margin, FY2023: 38.97%Gross margin, FY2024: 23.07%Gross margin, FY2025: 34.65%Operating margin, FY2023: -1523.94%Operating margin, FY2024: -1354.28%Operating margin, FY2025: -959.05%Net margin, FY2023: -1501.78%Net margin, FY2024: -1288.25%Net margin, FY2025: -946.22%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2023 38.97%. Gross margin FY2024 23.07%. Gross margin FY2025 34.65%. Operating margin FY2023 -1523.94%. Operating margin FY2024 -1354.28%. Operating margin FY2025 -959.05%. Net margin FY2023 -1501.78%. Net margin FY2024 -1288.25%. Net margin FY2025 -946.22%.

Income trends

Revenue

13.11M USD+29.85%

Operating income

−125.7M USD+8.05%

Net income

−124.02M USD+4.63%
Income trends across reported periods28.09M USD−31.84M USD−91.76M USD−151.68M USDRevenue, FY2023: 7.77M USDRevenue, FY2024: 10.09M USDRevenue, FY2025: 13.11M USDOperating income, FY2021: −92.31M USDOperating income, FY2022: −112.09M USDOperating income, FY2023: −118.38M USDOperating income, FY2024: −136.7M USDOperating income, FY2025: −125.7M USDNet income, FY2021: −92.29M USDNet income, FY2022: −110.22M USDNet income, FY2023: −116.66M USDNet income, FY2024: −130.04M USDNet income, FY2025: −124.02M USDFY2021FY2022FY2023FY2024FY2025
Revenue FY2023 7.77M USD. Revenue FY2024 10.09M USD. Revenue FY2025 13.11M USD. Operating income FY2021 −92.31M USD. Operating income FY2022 −112.09M USD. Operating income FY2023 −118.38M USD. Operating income FY2024 −136.7M USD. Operating income FY2025 −125.7M USD. Net income FY2021 −92.29M USD. Net income FY2022 −110.22M USD. Net income FY2023 −116.66M USD. Net income FY2024 −130.04M USD. Net income FY2025 −124.02M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Revenue13.11M USD10.09M USD7.77M USD
Cost of goods sold8.57M USD7.77M USD4.74M USD
Gross profit4.54M USD2.33M USD3.03M USD
Research and development44.49M USD40.45M USD86.66M USD81.88M USD68.84M USD
Selling, general, and administrative85.76M USD40.1M USD34.75M USD30.22M USD23.47M USD
Operating expenses130.25M USD139.03M USD121.41M USD112.09M USD92.31M USD
Interest income4.15M USD1.87M USD25K USD
Interest expense89K USD
Depreciation and amortization1.93M USD3.42M USD4.29M USD1.25M USD50K USD
Operating income−125.7M USD−136.7M USD−118.38M USD−112.09M USD−92.31M USD
Net income−124.02M USD−130.04M USD−116.66M USD−110.22M USD−92.29M USD

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
45%
5 beats, 5 misses, 1 met estimate
Average EPS surprise
-38.28%
11 comparable reports
Latest EPS result
-2.44
Estimate -2.64 · Beat by 7.58%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates-2.07-4.83-7.6-10.36Q1 '25MissQ2 '25BeatQ3 '25MissQ4 '25MetQ1 '26MissQ2 '26MissQ3 '26BeatQ4 '26Estimate
Q1 2025, reported Mar 18, 2025: actual -9.77, estimate -6.23, surprise -56.82%, Miss. Q2 2025, reported May 12, 2025: actual -2.84, estimate -3.23, surprise +12.07%, Beat. Q3 2025, reported Aug 12, 2025: actual -3.86, estimate -3.1, surprise -24.52%, Miss. Q4 2025, reported Nov 10, 2025: actual -3.59, estimate -3.59, surprise 0.00%, Met estimate. Q1 2026, reported Mar 12, 2026: actual -3.98, estimate -3.16, surprise -25.95%, Miss. Q2 2026, reported May 11, 2026: actual -2.93, estimate -2.54, surprise -15.35%, Miss. Q3 2026, reported Aug 10, 2026: actual -2.44, estimate -2.64, surprise +7.58%, Beat. Q4 2026, reported Nov 9, 2026: actual —, estimate -2.5, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates15.12M10.64M6.17M1.7MQ1 '25MissQ2 '25MissQ3 '25MissQ4 '25BeatQ1 '26BeatQ2 '26BeatQ3 '26BeatQ4 '26Estimate
Q1 2025, reported Mar 18, 2025: actual 2.58M USD, estimate 3.2M USD, surprise -19.31%, Miss. Q2 2025, reported May 12, 2025: actual 2.43M USD, estimate 2.6M USD, surprise -6.58%, Miss. Q3 2025, reported Aug 12, 2025: actual 2M USD, estimate 2.43M USD, surprise -17.89%, Miss. Q4 2025, reported Nov 10, 2025: actual 3.29M USD, estimate 2.3M USD, surprise +43.04%, Beat. Q1 2026, reported Mar 12, 2026: actual 5.39M USD, estimate 2.97M USD, surprise +81.69%, Beat. Q2 2026, reported May 11, 2026: actual 6.88M USD, estimate 6.13M USD, surprise +12.29%, Beat. Q3 2026, reported Aug 10, 2026: actual 13.54M USD, estimate 7.72M USD, surprise +75.38%, Beat. Q4 2026, reported Nov 9, 2026: actual —, estimate 14.15M USD, surprise —, Comparison unavailable.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Analyst price target

Average target

$27.00

115.14% upside
Past 12 months12-month forecastHigh $27.00Average $27.00Low $27.00

Rating distribution

7 ratings
Strong buy00%
Buy686%
Hold114%
Sell00%
Strong sell00%

Recent analyst actions

2 institutions
Noble Capital MarketsmaintainOutperform
Alliance Global PartnersmaintainBuy

TNXP news

Corporate actions

Corporate action history

Stock split

Effective Feb 5, 2025

1:100

Stock split

Effective Jun 10, 2024

1:32

Stock split

Effective May 10, 2023

4:25

Stock split

Effective May 17, 2022

1:32

Stock split

Effective Nov 1, 2019

1:10

Stock split

Effective Nov 28, 2018

1:10

TNXP peers

ETFs holding TNXP

Funds reporting this stock among their holdings, ordered by reported position size.

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