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Taysha Gene Therapies, Inc. logo

Taysha Gene Therapies, Inc.

TSHA

NASDAQHealthcareBiotechnology

Open in GoAI

Previous close

$6.09

−$0.02 · -0.33%

Aug 21, 4:00 PM ET

TSHA company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Hold

Wait — insufficient conviction to act

Valuation

53

Fair Value

Momentum

61

Gaining

Sentiment

69

Bullish

Risk resilience

52

Elevated Risk

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AI-generated, informational only, and not investment advice.

Company profile

Industry
Biotechnology
Sector
Healthcare
Headquarters
US

Market position

Day range

Current $6.09

52-week range

Current $6.09

Open
$6.18
Previous close
$6.11
Volume
2.83M
Market cap
1.95B USD
50-day average
$6.1434
-0.87% below average
200-day average
$5.3519
+13.79% above average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
1.46B USD
P/E (TTM)
-14.41×
P/B (TTM)
5.8×
P/S (TTM)
355.14×
EV / EBITDA
-13.52×
Earnings yield
-6.20%
Free cash flow yield
-5.34%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
83.96%
Operating margin
-2792.32%
Net margin
-2728.04%
Return on equity
-44.14%
Return on assets
-31.75%
Return on invested capital
-34.88%

Financial health

Debt / equity
0.14×
Current ratio
12.23×

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends774%-1921%-4615%-7309%Gross margin, FY2022: 0.60%Gross margin, FY2023: 100.00%Gross margin, FY2024: 100.00%Gross margin, FY2025: 100.00%Operating margin, FY2022: -5037.05%Operating margin, FY2023: -468.83%Operating margin, FY2024: -1097.55%Operating margin, FY2025: -1130.65%Net margin, FY2022: -6635.25%Net margin, FY2023: -722.06%Net margin, FY2024: -1071.62%Net margin, FY2025: -1115.27%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2022 0.60%. Gross margin FY2023 100.00%. Gross margin FY2024 100.00%. Gross margin FY2025 100.00%. Operating margin FY2022 -5037.05%. Operating margin FY2023 -468.83%. Operating margin FY2024 -1097.55%. Operating margin FY2025 -1130.65%. Net margin FY2022 -6635.25%. Net margin FY2023 -722.06%. Net margin FY2024 -1071.62%. Net margin FY2025 -1115.27%.

Income trends

Revenue

9.77M USD+17.28%

Operating income

−110.5M USD-20.82%

Net income

−109M USD-22.06%
Income trends across reported periods34.45M USD−41.54M USD−117.53M USD−193.52M USDRevenue, FY2022: 2.5M USDRevenue, FY2023: 15.45M USDRevenue, FY2024: 8.33M USDRevenue, FY2025: 9.77M USDOperating income, FY2021: −173.27M USDOperating income, FY2022: −126.03M USDOperating income, FY2023: −72.44M USDOperating income, FY2024: −91.46M USDOperating income, FY2025: −110.5M USDNet income, FY2021: −174.52M USDNet income, FY2022: −166.01M USDNet income, FY2023: −111.57M USDNet income, FY2024: −89.3M USDNet income, FY2025: −109M USDFY2021FY2022FY2023FY2024FY2025
Revenue FY2022 2.5M USD. Revenue FY2023 15.45M USD. Revenue FY2024 8.33M USD. Revenue FY2025 9.77M USD. Operating income FY2021 −173.27M USD. Operating income FY2022 −126.03M USD. Operating income FY2023 −72.44M USD. Operating income FY2024 −91.46M USD. Operating income FY2025 −110.5M USD. Net income FY2021 −174.52M USD. Net income FY2022 −166.01M USD. Net income FY2023 −111.57M USD. Net income FY2024 −89.3M USD. Net income FY2025 −109M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Revenue9.77M USD8.33M USD15.45M USD2.5M USD—
Cost of goods sold———2.49M USD—
Gross profit9.77M USD8.33M USD15.45M USD15K USD—
Research and development86.4M USD66M USD56.78M USD91.17M USD131.94M USD
Selling, general, and administrative33.87M USD28.95M USD30.05M USD34.87M USD41.32M USD
Operating expenses120.27M USD99.79M USD87.89M USD126.04M USD173.27M USD
Interest income9.22M USD6.94M USD3.57M USD249K USD172K USD
Interest expense63K USD102K USD5M USD3.8M USD1.43M USD
Depreciation and amortization1.15M USD1.25M USD1.37M USD2.49M USD492K USD
Operating income−110.5M USD−91.46M USD−72.44M USD−126.03M USD−173.27M USD
Net income−109M USD−89.3M USD−111.57M USD−166.01M USD−174.52M USD

Company facts updated Aug 24, 2026.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Analyst price target

Average target

$14.00

129.89% upside
Past 12 months12-month forecastHigh $15.00Average $14.00Low $13.00

TSHA peers

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ISRG

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$378.81

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Sanofi logo

SNY

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$45.85

+1.55%

Regeneron Pharmaceuticals, Inc. logo

REGN

Regeneron Pharmaceuticals, Inc.

$834.04

+0.90%

ETFs holding TSHA

Funds reporting this stock among their holdings, ordered by reported position size.

Vanguard Morningstar Total Stock Market ETF logoVanguard Morningstar Total Stock Market ETFVTI
Market value
53.82M
Weight
0.00%
AUM
2.3T USD
Expense ratio
0.03%
Price / 1D
$378.24+0.44%
iShares Russell 2000 ETF logoiShares Russell 2000 ETFIWM
Market value
37.57M
Weight
0.05%
AUM
81.62B USD
Expense ratio
0.19%
Price / 1D
$299.96+0.77%
State Street SPDR S&P Biotech ETF logoState Street SPDR S&P Biotech ETFXBI
Market value
35.69M
Weight
0.31%
AUM
11.39B USD
Expense ratio
0.35%
Price / 1D
$165.73+1.44%
Vanguard Extended Market ETF logoVanguard Extended Market ETFVXF
Market value
17.87M
Weight
0.02%
AUM
93.7B USD
Expense ratio
0.05%
Price / 1D
$245.53+0.82%
iShares Russell 2000 Growth ETF logoiShares Russell 2000 Growth ETFIWO
Market value
13.52M
Weight
0.09%
AUM
15.16B USD
Expense ratio
0.24%
Price / 1D
$387.37+1.24%
iShares Biotechnology ETF logoiShares Biotechnology ETFIBB
Market value
12.13M
Weight
0.11%
AUM
10.75B USD
Expense ratio
0.44%
Price / 1D
$213.56+1.29%
Vanguard Russell 2000 ETF logoVanguard Russell 2000 ETFVTWO
Market value
7.89M
Weight
0.04%
AUM
17.4B USD
Expense ratio
0.06%
Price / 1D
$121.25+0.74%
Schwab U.S. Small-Cap ETF logoSchwab U.S. Small-Cap ETFSCHA
Market value
7.79M
Weight
0.03%
AUM
23.1B USD
Expense ratio
0.03%
Price / 1D
$34.83+0.52%

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