Wave Life Sciences Ltd. logo

Wave Life Sciences Ltd.

WVE

NASDAQHealthcareBiotechnology

Previous close

$5.29

+$0.04 · +0.76%

Aug 21, 4:00 PM ET

WVE company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Hold

Wait — insufficient conviction to act

Valuation

53

Fair Value

Momentum

28

Weakening

Sentiment

64

Bullish

Risk resilience

42

Elevated Risk

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Company profile

Company website

Wave Life Sciences Ltd., a clinical-stage biotechnology company, designs, develops, and commercializes ribonucleic acid (RNA) medicines through PRISM, a discovery and drug development platform. The company’s medicines platform, PRISM combines multiple modalities, chemistry innovation, and deep insights into human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. It is developing WVE-006, a GalNAc-conjugated RNA editing oligonucleotide for the treatment of alpha-1 antitrypsin deficiency; WVE-007, a GalNAc-conjugated small interfering RNA designed to silence INHBE mRNA targeting obesity; WVE-008, a GalNAc-conjugated RNA editing oligonucleotide for the treatment of liver disease; WVE-N531, an exon splicing oligonucleotide for the treatment of Duchenne muscular dystrophy; and WVE-003, an allele-selective oligonucleotide for the treatment of Huntington’s disease (HD). The company has collaboration agreements with GlaxoSmithKline for the research, development, and commercialization of oligonucleotide therapeutics; Takeda Pharmaceutical Company Limited for the research, development, and commercialization of oligonucleotide therapeutics for disorders of the Central Nervous System; and Asuragen, Inc. for the development and potential commercialization of companion diagnostics for investigational allele-selective therapeutic programs targeting HD. Wave Life Sciences Ltd. was founded in 2012 and is based in Singapore.

Industry
Biotechnology
Sector
Healthcare
Headquarters
US
CEO
Paul Bolno
Listed since
Nov 11, 2015
Employees
317

Market position

Day range

Current $5.29

52-week range

Current $5.29

Open
$5.32
Previous close
$5.25
Volume
2.72M
0.78× average
Average volume
3.48M
Average daily volume
Market cap
1.04B USD
Beta
-1.29
Market reference 1
50-day average
$5.8136
-9.01% below average
200-day average
$9.4283
-43.89% below average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
2.28B USD
P/E (TTM)
-4.85×
P/B (TTM)
2.36×
P/S (TTM)
15.95×
EV / EBITDA
-11.67×
Earnings yield
-7.13%
Free cash flow yield
-6.54%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
96.54%
Operating margin
-333.36%
Net margin
-309.73%
Return on equity
-38.84%
Return on assets
-32.01%
Return on invested capital
-39.03%

Financial health

Debt / equity
0.1×
Current ratio
6.47×

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends556%-1268%-3092%-4915%Gross margin, FY2021: 100.00%Gross margin, FY2022: 100.00%Gross margin, FY2023: 100.00%Gross margin, FY2024: 100.00%Gross margin, FY2025: 79.28%Operating margin, FY2021: -310.07%Operating margin, FY2022: -4459.30%Operating margin, FY2023: -60.01%Operating margin, FY2024: -101.94%Operating margin, FY2025: -504.09%Net margin, FY2021: -298.42%Net margin, FY2022: -4434.72%Net margin, FY2023: -50.76%Net margin, FY2024: -89.57%Net margin, FY2025: -478.33%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2021 100.00%. Gross margin FY2022 100.00%. Gross margin FY2023 100.00%. Gross margin FY2024 100.00%. Gross margin FY2025 79.28%. Operating margin FY2021 -310.07%. Operating margin FY2022 -4459.30%. Operating margin FY2023 -60.01%. Operating margin FY2024 -101.94%. Operating margin FY2025 -504.09%. Net margin FY2021 -298.42%. Net margin FY2022 -4434.72%. Net margin FY2023 -50.76%. Net margin FY2024 -89.57%. Net margin FY2025 -478.33%.

Income trends

Revenue

42.73M USD-60.55%

Operating income

−215.38M USD-95.09%

Net income

−204.38M USD-110.68%
Income trends across reported periods146.17M USD14.7M USD−116.78M USD−248.25M USDRevenue, FY2021: 40.96M USDRevenue, FY2022: 3.65M USDRevenue, FY2023: 113.31M USDRevenue, FY2024: 108.3M USDRevenue, FY2025: 42.73M USDOperating income, FY2021: −127.02M USDOperating income, FY2022: −162.72M USDOperating income, FY2023: −68M USDOperating income, FY2024: −110.4M USDOperating income, FY2025: −215.38M USDNet income, FY2021: −122.25M USDNet income, FY2022: −161.82M USDNet income, FY2023: −57.51M USDNet income, FY2024: −97.01M USDNet income, FY2025: −204.38M USDFY2021FY2022FY2023FY2024FY2025
Revenue FY2021 40.96M USD. Revenue FY2022 3.65M USD. Revenue FY2023 113.31M USD. Revenue FY2024 108.3M USD. Revenue FY2025 42.73M USD. Operating income FY2021 −127.02M USD. Operating income FY2022 −162.72M USD. Operating income FY2023 −68M USD. Operating income FY2024 −110.4M USD. Operating income FY2025 −215.38M USD. Net income FY2021 −122.25M USD. Net income FY2022 −161.82M USD. Net income FY2023 −57.51M USD. Net income FY2024 −97.01M USD. Net income FY2025 −204.38M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Revenue42.73M USD108.3M USD113.31M USD3.65M USD40.96M USD
Cost of goods sold8.85M USD
Gross profit33.88M USD108.3M USD113.31M USD3.65M USD40.96M USD
Research and development182.78M USD159.68M USD130.01M USD115.86M USD121.88M USD
Selling, general, and administrative75.33M USD59.02M USD51.29M USD50.51M USD46.11M USD
Operating expenses249.26M USD218.71M USD181.3M USD166.37M USD167.98M USD
Interest income10.48M USD30K USD
Depreciation and amortization8.85M USD8.66M USD9.21M USD10.11M USD9.84M USD
Operating income−215.38M USD−110.4M USD−68M USD−162.72M USD−127.02M USD
Net income−204.38M USD−97.01M USD−57.51M USD−161.82M USD−122.25M USD

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
27%
3 beats, 8 misses, 0 met estimates
Average EPS surprise
+13.98%
11 comparable reports
Latest EPS result
-0.34
Estimate -0.3 · Miss by 13.43%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates0.210.01-0.18-0.38Q1 '25BeatQ2 '25MissQ3 '25MissQ4 '25MissQ1 '26MissQ2 '26BeatQ3 '26MissQ4 '26Estimate
Q1 2025, reported Mar 4, 2025: actual 0.17, estimate -0.17, surprise +200.00%, Beat. Q2 2025, reported May 8, 2025: actual -0.29, estimate -0.27, surprise -7.41%, Miss. Q3 2025, reported Jul 30, 2025: actual -0.31, estimate -0.29, surprise -6.90%, Miss. Q4 2025, reported Nov 10, 2025: actual -0.32, estimate -0.3, surprise -6.67%, Miss. Q1 2026, reported Feb 26, 2026: actual -0.3, estimate -0.28, surprise -7.14%, Miss. Q2 2026, reported Apr 28, 2026: actual -0.13, estimate -0.34, surprise +61.76%, Beat. Q3 2026, reported Jul 30, 2026: actual -0.34, estimate -0.3, surprise -13.43%, Miss. Q4 2026, reported Nov 9, 2026: actual —, estimate -0.33, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates90.27M60.82M31.38M1.93MQ1 '25BeatQ2 '25MissQ3 '25MissQ4 '25MissQ1 '26BeatQ2 '26BeatQ3 '26MissQ4 '26Estimate
Q1 2025, reported Mar 4, 2025: actual 83.75M USD, estimate 12.17M USD, surprise +588.34%, Beat. Q2 2025, reported May 8, 2025: actual 9.18M USD, estimate 14.42M USD, surprise -36.35%, Miss. Q3 2025, reported Jul 30, 2025: actual 8.7M USD, estimate 9.85M USD, surprise -11.69%, Miss. Q4 2025, reported Nov 10, 2025: actual 7.61M USD, estimate 16.35M USD, surprise -53.45%, Miss. Q1 2026, reported Feb 26, 2026: actual 17.24M USD, estimate 16.06M USD, surprise +7.39%, Beat. Q2 2026, reported Apr 28, 2026: actual 38.25M USD, estimate 8.45M USD, surprise +352.57%, Beat. Q3 2026, reported Jul 30, 2026: actual 2.27M USD, estimate 7.45M USD, surprise -69.50%, Miss. Q4 2026, reported Nov 9, 2026: actual —, estimate 4.71M USD, surprise —, Comparison unavailable.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Rating distribution

25 ratings
Strong buy14%
Buy2392%
Hold14%
Sell00%
Strong sell00%

Recent analyst actions

12 institutions

ETFs holding WVE

Funds reporting this stock among their holdings, ordered by reported position size.

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