Xeris Biopharma Holdings, Inc. logo

Xeris Biopharma Holdings, Inc.

XERS

NASDAQHealthcareBiotechnology

Previous close

$8.70

+$0.10 · +1.16%

Aug 21, 4:00 PM ET

XERS company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Buy

Favorable setup — positive multi-factor alignment

Valuation

87

Deep Value

Momentum

61

Gaining

Sentiment

50

Mixed

Risk resilience

62

Moderate Risk

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Company profile

Company website

Xeris Biopharma Holdings, Inc. operates as a biopharmaceutical company, focusing on the development and commercialization of therapeutic solutions for individuals across the fields of endocrinology, neurology, and gastroenterology. Its current portfolio includes: Gvoke: A ready-to-administer liquid glucagon designed to treat severe hypoglycemia. Keveyis: A therapy addressing hyperkalemic, hypokalemic, and related forms of primary periodic paralysis. Recorlev: A cortisol synthesis inhibitor approved for managing endogenous hypercortisolemia in adult patients with Cushing's syndrome. Beyond its marketed products, the company maintains an active development pipeline. This pipeline seeks to broaden the applications and indications for existing treatments and introduce novel pharmaceuticals leveraging its proprietary XeriSol and XeriJect formulation technology platforms. Founded in 2005, Xeris Biopharma is headquartered in Chicago, Illinois.

Industry
Biotechnology
Sector
Healthcare
Headquarters
US
CEO
John Shannon
Listed since
Jun 21, 2018
Employees
435

Market position

Day range

Current $8.70

52-week range

Current $8.70

Open
$8.63
Previous close
$8.60
Volume
1.56M
0.86× average
Average volume
1.81M
Average daily volume
Market cap
1.5B USD
Beta
0.85
Market reference 1
50-day average
$8.0848
+7.61% above average
200-day average
$7.0119
+24.07% above average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
1.19B USD
P/E (TTM)
-89.6×
P/B (TTM)
-154.47×
P/S (TTM)
4.48×
EV / EBITDA
93.32×
Earnings yield
0.04%
Free cash flow yield
2.22%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
83.34%
Operating margin
10.91%
Net margin
-5.12%
Return on equity
4.05%
Return on assets
0.14%
Return on invested capital
8.89%

Financial health

Debt / equity
-29.74×
Current ratio
2.19×

Earnings

EPS beat rate
64%
7 beats, 4 misses, 0 met estimates
Average EPS surprise
-84.06%
11 comparable reports
Latest EPS result
-0.18
Estimate 0.01 · Miss by 1582.70%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates0.1-0.01-0.11-0.22Q1 '25BeatQ2 '25BeatQ3 '25BeatQ4 '25MissQ1 '26BeatQ2 '26BeatQ3 '26MissQ4 '26Estimate
Q1 2025, reported Mar 6, 2025: actual -0.03, estimate -0.08, surprise +62.50%, Beat. Q2 2025, reported May 8, 2025: actual -0.06, estimate -0.07, surprise +14.29%, Beat. Q3 2025, reported Aug 7, 2025: actual -0.01, estimate -0.03, surprise +66.67%, Beat. Q4 2025, reported Nov 6, 2025: actual 0.004, estimate 0.01, surprise -65.00%, Miss. Q1 2026, reported Mar 2, 2026: actual 0.06, estimate 0.03, surprise +100.00%, Beat. Q2 2026, reported May 7, 2026: actual 0.01, estimate -0.003, surprise +464.96%, Beat. Q3 2026, reported Aug 6, 2026: actual -0.18, estimate 0.012, surprise -1582.70%, Miss. Q4 2026, reported Nov 5, 2026: actual —, estimate 0.02, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates105.62M87.36M69.1M50.84MQ1 '25BeatQ2 '25BeatQ3 '25MissQ4 '25MissQ1 '26BeatQ2 '26BeatQ3 '26BeatQ4 '26Estimate
Q1 2025, reported Mar 6, 2025: actual 60.1M USD, estimate 54.9M USD, surprise +9.47%, Beat. Q2 2025, reported May 8, 2025: actual 60.12M USD, estimate 57.61M USD, surprise +4.36%, Beat. Q3 2025, reported Aug 7, 2025: actual 71.54M USD, estimate 72.25M USD, surprise -0.98%, Miss. Q4 2025, reported Nov 6, 2025: actual 74.38M USD, estimate 86M USD, surprise -13.51%, Miss. Q1 2026, reported Mar 2, 2026: actual 85.81M USD, estimate 82.2M USD, surprise +4.39%, Beat. Q2 2026, reported May 7, 2026: actual 82.45M USD, estimate 79.83M USD, surprise +3.28%, Beat. Q3 2026, reported Aug 6, 2026: actual 91M USD, estimate 90.13M USD, surprise +0.98%, Beat. Q4 2026, reported Nov 5, 2026: actual —, estimate 101.56M USD, surprise —, Comparison unavailable.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Analyst price target

Average target

$12.00

37.93% upside
Past 12 months12-month forecastHigh $12.00Average $12.00Low $12.00

XERS peers

ETFs holding XERS

Funds reporting this stock among their holdings, ordered by reported position size.

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