X4 Pharmaceuticals, Inc. logo

X4 Pharmaceuticals, Inc.

XFOR

NASDAQHealthcareBiotechnology

Previous close

$4.04

+$0.01 · +0.25%

Aug 21, 4:00 PM ET

XFOR company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Buy

Favorable setup — positive multi-factor alignment

Valuation

78

Undervalued

Momentum

73

Gaining

Sentiment

50

Mixed

Risk resilience

58

Elevated Risk

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Company profile

Company website

X4 Pharmaceuticals, Inc. is a biopharmaceutical firm committed to the discovery, development, and commercialization of innovative therapies for uncommon immune system disorders. Its primary drug candidate, XOLREMDI (also known as mavorixafor), is an orally administered, small-molecule antagonist specifically designed to target the chemokine receptor CXCR4. This compound is currently undergoing Phase 3 clinical trials for the management of WHIM syndrome, a rare immunodeficiency characterized by symptoms such as warts, hypogammaglobulinemia, recurrent infections, and myelokathexis. To broaden its global presence, the company has entered into several licensing agreements: A partnership with Abbisko Therapeutics Co Ltd. grants rights for the manufacturing and distribution of XOLREMDI in mainland China, Taiwan, Hong Kong, and Macau. Another agreement with Norgine covers the development, production, and commercialization of mavorixafor across Europe, Australia, and New Zealand. Furthermore, X4 Pharmaceuticals holds a comprehensive agreement with Genzyme Corporation concerning the CXCR4 receptor, allowing for the development and commercialization of licensed compounds for all medical applications, including therapeutic, preventive, and diagnostic uses. The company maintains its corporate headquarters in Boston, Massachusetts.

Industry
Biotechnology
Sector
Healthcare
Headquarters
US
CEO
Adam R. Craig
Listed since
Nov 16, 2017
Employees
45

Market position

Day range

Current $4.04

52-week range

Current $4.04

Open
$4.02
Previous close
$4.03
Volume
1.22M
1.89× average
Average volume
645.55K
Average daily volume
Market cap
381.05M USD
Beta
0.35
Market reference 1
50-day average
$4.0738
-0.83% below average
200-day average
$3.9197
+3.07% above average

Financials

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends237%-382%-1001%-1619%Gross margin, FY2024: 68.83%Gross margin, FY2025: 82.18%Operating margin, FY2024: -1423.58%Operating margin, FY2025: -247.44%Net margin, FY2024: -1464.61%Net margin, FY2025: -225.55%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2024 68.83%. Gross margin FY2025 82.18%. Operating margin FY2024 -1423.58%. Operating margin FY2025 -247.44%. Net margin FY2024 -1464.61%. Net margin FY2025 -225.55%.

Income trends

Revenue

35.11M USD+1273.21%

Operating income

−86.88M USD-138.68%

Net income

−79.2M USD-111.48%
Income trends across reported periods49.38M USD−7.68M USD−64.73M USD−121.79M USDRevenue, FY2024: 2.56M USDRevenue, FY2025: 35.11M USDOperating income, FY2021: −75.35M USDOperating income, FY2022: −87.57M USDOperating income, FY2023: −107.52M USDOperating income, FY2024: −36.4M USDOperating income, FY2025: −86.88M USDNet income, FY2021: −88.7M USDNet income, FY2022: −93.87M USDNet income, FY2023: −101.17M USDNet income, FY2024: −37.45M USDNet income, FY2025: −79.2M USDFY2021FY2022FY2023FY2024FY2025
Revenue FY2024 2.56M USD. Revenue FY2025 35.11M USD. Operating income FY2021 −75.35M USD. Operating income FY2022 −87.57M USD. Operating income FY2023 −107.52M USD. Operating income FY2024 −36.4M USD. Operating income FY2025 −86.88M USD. Net income FY2021 −88.7M USD. Net income FY2022 −93.87M USD. Net income FY2023 −101.17M USD. Net income FY2024 −37.45M USD. Net income FY2025 −79.2M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Revenue35.11M USD2.56M USD
Cost of goods sold6.26M USD797K USD1.89M USD
Gross profit28.86M USD1.76M USD−1.89M USD
Research and development72.22M USD81.64M USD72.02M USD61.06M USD48.76M USD
Selling, general, and administrative43.52M USD61.52M USD35.51M USD27.02M USD24.7M USD
Operating expenses115.74M USD38.16M USD107.52M USD87.57M USD73.46M USD
Interest income4.58M USD5.77M USD4.58M USD219K USD10K USD
Interest expense8.88M USD8.77M USD5.78M USD3.99M USD3.64M USD
Depreciation and amortization1.28M USD796K USD419K USD513K USD1.89M USD
Operating income−86.88M USD−36.4M USD−107.52M USD−87.57M USD−75.35M USD
Net income−79.2M USD−37.45M USD−101.17M USD−93.87M USD−88.7M USD

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
55%
6 beats, 5 misses, 0 met estimates
Average EPS surprise
-643.23%
11 comparable reports
Latest EPS result
-0.13
Estimate -0.18 · Beat by 26.14%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates0.52-1.82-4.15-6.49Q1 '25MissQ2 '25BeatQ3 '25BeatQ4 '25BeatQ1 '26BeatQ2 '26BeatQ3 '26BeatQ4 '26Estimate
Q1 2025, reported Mar 25, 2025: actual -6.01, estimate -5.11, surprise -17.61%, Miss. Q2 2025, reported May 1, 2025: actual 0.04, estimate -4.13, surprise +100.97%, Beat. Q3 2025, reported Aug 8, 2025: actual -3.47, estimate -4.53, surprise +23.40%, Beat. Q4 2025, reported Nov 5, 2025: actual -0.69, estimate -0.79, surprise +12.66%, Beat. Q1 2026, reported Mar 17, 2026: actual -0.22, estimate -0.36, surprise +38.89%, Beat. Q2 2026, reported May 6, 2026: actual -0.16, estimate -0.2, surprise +20.00%, Beat. Q3 2026, reported Aug 7, 2026: actual -0.13, estimate -0.176, surprise +26.14%, Beat. Q4 2026, reported Nov 4, 2026: actual —, estimate -0.2, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates31.03M20.98M10.94M899.02KQ1 '25BeatQ2 '25BeatQ3 '25BeatQ4 '25MissQ1 '26BeatQ2 '26MissQ3 '26BeatQ4 '26Estimate
Q1 2025, reported Mar 25, 2025: actual 1.43M USD, estimate 1.06M USD, surprise +35.58%, Beat. Q2 2025, reported May 1, 2025: actual 28.81M USD, estimate 11.58M USD, surprise +148.75%, Beat. Q3 2025, reported Aug 8, 2025: actual 1.97M USD, estimate 1.62M USD, surprise +21.82%, Beat. Q4 2025, reported Nov 5, 2025: actual 1.77M USD, estimate 1.9M USD, surprise -7.22%, Miss. Q1 2026, reported Mar 17, 2026: actual 2.57M USD, estimate 1.73M USD, surprise +48.18%, Beat. Q2 2026, reported May 6, 2026: actual 2.71M USD, estimate 3.2M USD, surprise -15.38%, Miss. Q3 2026, reported Aug 7, 2026: actual 8.81M USD, estimate 2.42M USD, surprise +263.88%, Beat. Q4 2026, reported Nov 4, 2026: actual —, estimate 2.3M USD, surprise —, Comparison unavailable.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Analyst price target

Average target

$11.67

188.86% upside
Past 12 months12-month forecastHigh $12.00Average $11.67Low $11.00

Rating distribution

13 ratings
Strong buy00%
Buy1292%
Hold18%
Sell00%
Strong sell00%

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