Zenas BioPharma, Inc. logo

Zenas BioPharma, Inc.

ZBIO

NASDAQHealthcareBiotechnology

Previous close

$32.29

+$0.67 · +2.12%

Aug 21, 4:00 PM ET

ZBIO company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Hold

Wait — insufficient conviction to act

Valuation

52

Fair Value

Momentum

64

Gaining

Sentiment

37

Bearish

Risk resilience

48

Elevated Risk

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Company profile

Company website

Zenas BioPharma, Inc. functions as a clinical-stage biopharmaceutical firm, concentrating on the creation and market introduction of innovative, immunology-based treatments. The company's primary investigational therapy is obexelimab, a distinctive bifunctional monoclonal antibody intended to address multiple diseases such as immunoglobulin G4-related disease, multiple sclerosis, systemic lupus erythematosus, and warm autoimmune hemolytic anemia. Its developmental portfolio also features ZB002, an anti-TNFa monoclonal antibody; ZB004, a cytotoxic T-lymphocyte-associated antigen 4-immunoglobulin fusion; ZB001, an anti-insulin-like growth factor-1 receptor monoclonal antibody; and ZB005, an anti-active complement component 1s monoclonal antibody. Established in 2019, the entity was formerly recognized as Zenas BioPharma (Cayman) Limited before adopting its current name, Zenas BioPharma, Inc., in August 2023. Its headquarters are located in Waltham, Massachusetts.

Industry
Biotechnology
Sector
Healthcare
Headquarters
US
CEO
Leon Oliver Moulder Jr.
Listed since
Sep 13, 2024
Employees
167

Market position

Day range

Current $32.29

52-week range

Current $32.29

Open
$31.83
Previous close
$31.62
Volume
808.72K
1.08× average
Average volume
746.47K
Average daily volume
Market cap
2.04B USD
Beta
-1.01
Market reference 1
50-day average
$28.0816
+14.99% above average
200-day average
$26.0451
+23.98% above average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
1.59B USD
P/E (TTM)
-3.36×
P/B (TTM)
8.25×
P/S (TTM)
2,038.58×
EV / EBITDA
-4.3×
Earnings yield
-23.26%
Free cash flow yield
-10.61%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
-5972.60%
Operating margin
-47557.30%
Net margin
-48438.40%
Return on equity
-156.00%
Return on assets
-98.46%
Return on invested capital
-65.61%

Financial health

Debt / equity
0.91×
Current ratio
5.61×
Altman Z-score
-0.36
Piotroski F-score
3 of 9

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends488%-1063%-2614%-4165%Gross margin, FY2023: 100.00%Gross margin, FY2024: -2682.78%Gross margin, FY2025: 100.00%Operating margin, FY2023: -74.29%Operating margin, FY2024: -3277.76%Operating margin, FY2025: -2113.85%Net margin, FY2023: -74.25%Net margin, FY2024: -3139.76%Net margin, FY2025: -3777.37%FY2022FY2023FY2024FY2025
Gross margin FY2023 100.00%. Gross margin FY2024 -2682.78%. Gross margin FY2025 100.00%. Operating margin FY2023 -74.29%. Operating margin FY2024 -3277.76%. Operating margin FY2025 -2113.85%. Net margin FY2023 -74.25%. Net margin FY2024 -3139.76%. Net margin FY2025 -3777.37%.

Income trends

Revenue

10M USD+100.00%

Operating income

−211.39M USD-28.98%

Net income

−377.74M USD-140.62%
Income trends across reported periods92.77M USD−78.32M USD−249.42M USD−420.51M USDRevenue, FY2023: 50M USDRevenue, FY2024: 5M USDRevenue, FY2025: 10M USDOperating income, FY2022: −76.2M USDOperating income, FY2023: −37.15M USDOperating income, FY2024: −163.89M USDOperating income, FY2025: −211.39M USDNet income, FY2022: −119.28M USDNet income, FY2023: −37.12M USDNet income, FY2024: −156.99M USDNet income, FY2025: −377.74M USDFY2022FY2023FY2024FY2025
Revenue FY2023 50M USD. Revenue FY2024 5M USD. Revenue FY2025 10M USD. Operating income FY2022 −76.2M USD. Operating income FY2023 −37.15M USD. Operating income FY2024 −163.89M USD. Operating income FY2025 −211.39M USD. Net income FY2022 −119.28M USD. Net income FY2023 −37.12M USD. Net income FY2024 −156.99M USD. Net income FY2025 −377.74M USD.
Metric (USD)FY2025FY2024FY2023FY2022
Revenue10M USD5M USD50M USD
Cost of goods sold139.14M USD61.69M USD
Gross profit10M USD−134.14M USD50M USD−61.69M USD
Research and development168.06M USD139.14M USD60.03M USD62.69M USD
Selling, general, and administrative53.32M USD29.75M USD17.11M USD13.51M USD
Operating expenses221.39M USD29.75M USD87.15M USD14.51M USD
Interest income12.15M USD
Interest expense7.33M USD
Depreciation and amortization56K USD137K USD113K USD78K USD
Operating income−211.39M USD−163.89M USD−37.15M USD−76.2M USD
Net income−377.74M USD−156.99M USD−37.12M USD−119.28M USD

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
25%
2 beats, 6 misses, 0 met estimates
Average EPS surprise
-52.31%
8 comparable reports
Latest EPS result
-1.77
Estimate -1.12 · Miss by 58.04%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates-0.68-2.07-3.45-4.84Q2 '25BeatQ3 '25MissQ4 '25MissQ1 '26MissQ2 '26MissQ3 '26MissQ4 '26EstimateQ2 '27Estimate
Q2 2025, reported May 15, 2025: actual -0.8, estimate -1.11, surprise +27.93%, Beat. Q3 2025, reported Aug 12, 2025: actual -1.25, estimate -1.02, surprise -22.55%, Miss. Q4 2025, reported Nov 12, 2025: actual -1.22, estimate -0.87, surprise -40.23%, Miss. Q1 2026, reported Mar 16, 2026: actual -4.54, estimate -1.06, surprise -328.30%, Miss. Q2 2026, reported May 13, 2026: actual -1.46, estimate -1.37, surprise -6.57%, Miss. Q3 2026, reported Aug 12, 2026: actual -1.77, estimate -1.12, surprise -58.04%, Miss. Q4 2026, reported Nov 12, 2026: actual —, estimate -1.22, surprise —, Comparison unavailable. Q2 2027, reported Apr 12, 2027: actual —, estimate -1.23, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates30.97M20.93M10.89M850KQ2 '25BeatQ3 '25EstimateQ4 '25EstimateQ1 '26EstimateQ2 '26EstimateQ3 '26MissQ4 '26EstimateQ2 '27Estimate
Q2 2025, reported May 15, 2025: actual 10M USD, estimate 1.25M USD, surprise +700.00%, Beat. Q3 2025, reported Aug 12, 2025: actual —, estimate 3.75M USD, surprise —, Comparison unavailable. Q4 2025, reported Nov 12, 2025: actual —, estimate 28.75M USD, surprise —, Comparison unavailable. Q1 2026, reported Mar 16, 2026: actual —, estimate 13.33M USD, surprise —, Comparison unavailable. Q2 2026, reported May 13, 2026: actual —, estimate 25M USD, surprise —, Comparison unavailable. Q3 2026, reported Aug 12, 2026: actual 1M USD, estimate 15M USD, surprise -93.33%, Miss. Q4 2026, reported Nov 12, 2026: actual —, estimate 1.01M USD, surprise —, Comparison unavailable. Q2 2027, reported Apr 12, 2027: actual —, estimate 1.59M USD, surprise —, Comparison unavailable.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Analyst price target

Average target

$32.00

0.90% downside
Past 12 months12-month forecastHigh $32.00Average $32.00Low $32.00

Rating distribution

5 ratings
Strong buy00%
Buy480%
Hold120%
Sell00%
Strong sell00%

Recent analyst actions

5 institutions

ZBIO news

ZBIO peers

ETFs holding ZBIO

Funds reporting this stock among their holdings, ordered by reported position size.

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