Astellas Pharma Inc. logo

Astellas Pharma Inc.

4503.T

JPXHealthcareDrug Manufacturers - General

Latest quote

¥2,406.5

+¥19.50 · +0.82%

Aug 24, 3:30 PM JST

4503.T company overview

Regular session · JST · Market data may be delayed.

Company profile

Company website

Astellas Pharma Inc., a venerable Japanese pharmaceutical enterprise established in 1923 and headquartered in Tokyo, operates globally in the research, development, manufacturing, and commercialization of a diverse range of medications. Its extensive product lineup addresses critical health needs, including various oncology treatments such as XTANDI for prostate cancer, XOSPATA, an FLT3 inhibitor for specific relapsed or refractory acute myeloid leukemia, and PADCEV for advanced urothelial cancer. For urological conditions, Astellas offers Betanis/Myrbetriq/BETMIGA to manage symptoms of overactive bladder, mirabegron for neurogenic detrusor overactivity in children, and Vesicare for OAB. Other notable pharmaceuticals include Eligard for prostate cancer, Harnal/Omnic for benign prostatic hyperplasia, Evrenzo for anemia associated with chronic kidney disease, and the immunosuppressants Prograf/Advagraf/Graceptor/ASTAGRAF, vital for preventing organ transplant rejection. The company also markets Funguard/MYCAMINE, an antifungal agent. Astellas actively fosters innovation through numerous strategic collaborations and partnerships. These include clinical trial agreements with pharmaceutical giants like Merck & Co., Inc. and CytomX Therapeutics, Inc. Demonstrating a broader approach to health, they collaborate with BANDAI NAMCO Entertainment Inc. on developing a smartphone exercise support application. In the realm of scientific discovery, Astellas maintains a research alliance with Harvard University for joint therapeutic and technological advancements. Further research initiatives involve Actinium Pharmaceuticals, Inc. to advance targeted radiotherapies leveraging their Antibody Warhead Enabling platform, an agreement with Zenith Epigenetics Ltd. to evaluate ZEN-3694, and a collaboration with Cytokinetics, Incorporated. A significant strategic alliance and license agreement exist with Minovia Therapeutics Ltd. to research, develop, and commercialize cell therapies for mitochondrial dysfunction.

Industry
Drug Manufacturers - General
Sector
Healthcare
Headquarters
JP
CEO
Naoki Okamura
Listed since
May 15, 1949
Employees
14,099

Market position

Volume
4.26M
0.65× average
Average volume
6.54M
Average daily volume
Market cap
4.31T JPY
Beta
0.08
Market reference 1

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
4.8T JPY
P/E (TTM)
11.81×
P/B (TTM)
2.22×
P/S (TTM)
1.9×
EV / EBITDA
8.19×
Earnings yield
6.46%
Free cash flow yield
11.27%
Dividend yield
3.24%

Profitability & efficiency

Gross margin
74.71%
Operating margin
21.81%
Net margin
16.04%
Return on equity
15.92%
Return on assets
8.17%
Return on invested capital
12.52%

Financial health

Debt / equity
0.3×
Current ratio
1.17×
Altman Z-score
2.96
Piotroski F-score
8 of 9

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends90%58%25%-7%Gross margin, FY2022: 80.48%Gross margin, FY2023: 81.01%Gross margin, FY2024: 81.76%Gross margin, FY2025: 81.74%Gross margin, FY2026: 74.55%Operating margin, FY2022: 16.97%Operating margin, FY2023: 18.80%Operating margin, FY2024: 11.10%Operating margin, FY2025: 13.37%Operating margin, FY2026: 19.62%Net margin, FY2022: 9.57%Net margin, FY2023: 6.50%Net margin, FY2024: 1.06%Net margin, FY2025: 2.65%Net margin, FY2026: 13.63%FY2022FY2023FY2024FY2025FY2026
Gross margin FY2022 80.48%. Gross margin FY2023 81.01%. Gross margin FY2024 81.76%. Gross margin FY2025 81.74%. Gross margin FY2026 74.55%. Operating margin FY2022 16.97%. Operating margin FY2023 18.80%. Operating margin FY2024 11.10%. Operating margin FY2025 13.37%. Operating margin FY2026 19.62%. Net margin FY2022 9.57%. Net margin FY2023 6.50%. Net margin FY2024 1.06%. Net margin FY2025 2.65%. Net margin FY2026 13.63%.

Income trends

Revenue

2.14T JPY+11.87%

Operating income

419.7B JPY+64.15%

Net income

291.54B JPY+474.49%
Income trends across reported periods2.35T JPY1.5T JPY653.71B JPY−195.18B JPYRevenue, FY2022: 1.3T JPYRevenue, FY2023: 1.52T JPYRevenue, FY2024: 1.6T JPYRevenue, FY2025: 1.91T JPYRevenue, FY2026: 2.14T JPYOperating income, FY2022: 220.02B JPYOperating income, FY2023: 285.43B JPYOperating income, FY2024: 178.07B JPYOperating income, FY2025: 255.67B JPYOperating income, FY2026: 419.7B JPYNet income, FY2022: 124.09B JPYNet income, FY2023: 98.71B JPYNet income, FY2024: 17.05B JPYNet income, FY2025: 50.75B JPYNet income, FY2026: 291.54B JPYFY2022FY2023FY2024FY2025FY2026
Revenue FY2022 1.3T JPY. Revenue FY2023 1.52T JPY. Revenue FY2024 1.6T JPY. Revenue FY2025 1.91T JPY. Revenue FY2026 2.14T JPY. Operating income FY2022 220.02B JPY. Operating income FY2023 285.43B JPY. Operating income FY2024 178.07B JPY. Operating income FY2025 255.67B JPY. Operating income FY2026 419.7B JPY. Net income FY2022 124.09B JPY. Net income FY2023 98.71B JPY. Net income FY2024 17.05B JPY. Net income FY2025 50.75B JPY. Net income FY2026 291.54B JPY.
Metric (JPY)FY2026FY2025FY2024FY2023FY2022
Revenue2.14T JPY1.91T JPY1.6T JPY1.52T JPY1.3T JPY
Cost of goods sold544.41B JPY349.21B JPY292.49B JPY288.35B JPY253.01B JPY
Gross profit1.59T JPY1.56T JPY1.31T JPY1.23T JPY1.04T JPY
Research and development314.83B JPY327.7B JPY294.2B JPY276.1B JPY246B JPY
Selling, general, and administrative860.31B JPY843.03B JPY740.11B JPY630.27B JPY548.84B JPY
Operating expenses1.18T JPY1.31T JPY1.13T JPY944.84B JPY823.13B JPY
Interest income8.03B JPY7.87B JPY8.77B JPY8.11B JPY6.15B JPY
Interest expense14.07B JPY17.68B JPY9.37B JPY8.78B JPY4.95B JPY
Depreciation and amortization194.59B JPY199.13B JPY157.84B JPY105.74B JPY79.68B JPY
Operating income419.7B JPY255.67B JPY178.07B JPY285.43B JPY220.02B JPY
Net income291.54B JPY50.75B JPY17.05B JPY98.71B JPY124.09B JPY

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
64%
7 beats, 4 misses, 0 met estimates
Average EPS surprise
-48.80%
11 comparable reports
Latest EPS result
79.15
Estimate 52.62 · Beat by 50.42%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates89.8538.15-13.55-65.25Q1 '25MissQ2 '25BeatQ3 '25BeatQ4 '25BeatQ1 '26BeatQ2 '26MissQ3 '26BeatQ4 '26Estimate
Q1 2025, reported Feb 4, 2025: actual -54.55, estimate 18.94, surprise -388.01%, Miss. Q2 2025, reported Apr 25, 2025: actual 41.84, estimate 21.32, surprise +96.25%, Beat. Q3 2025, reported Jul 30, 2025: actual 38.22, estimate 19.87, surprise +92.35%, Beat. Q4 2025, reported Oct 30, 2025: actual 44.22, estimate 29.81, surprise +48.34%, Beat. Q1 2026, reported Feb 4, 2026: actual 56.04, estimate 45.93, surprise +22.01%, Beat. Q2 2026, reported Apr 27, 2026: actual 23.93, estimate 30.12, surprise -20.55%, Miss. Q3 2026, reported Aug 5, 2026: actual 79.15, estimate 52.62, surprise +50.42%, Beat. Q4 2026, reported Nov 4, 2026: actual —, estimate 62.1, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates666.55B583.31B500.08B416.84BQ1 '25BeatQ2 '25BeatQ3 '25BeatQ4 '25BeatQ1 '26BeatQ2 '26BeatQ3 '26BeatQ4 '26Estimate
Q1 2025, reported Feb 4, 2025: actual 517.41B JPY, estimate 447.53B JPY, surprise +15.62%, Beat. Q2 2025, reported Apr 25, 2025: actual 459.29B JPY, estimate 442.47B JPY, surprise +3.80%, Beat. Q3 2025, reported Jul 30, 2025: actual 505.79B JPY, estimate 454.5B JPY, surprise +11.29%, Beat. Q4 2025, reported Oct 30, 2025: actual 524.32B JPY, estimate 481.09B JPY, surprise +8.98%, Beat. Q1 2026, reported Feb 4, 2026: actual 573.06B JPY, estimate 529.88B JPY, surprise +8.15%, Beat. Q2 2026, reported Apr 27, 2026: actual 529.91B JPY, estimate 512.17B JPY, surprise +3.46%, Beat. Q3 2026, reported Aug 5, 2026: actual 640.91B JPY, estimate 559.53B JPY, surprise +14.54%, Beat. Q4 2026, reported Nov 4, 2026: actual —, estimate 575.84B JPY, surprise —, Comparison unavailable.

Corporate actions

Annual dividends per share

Cash distributions grouped by calendar year; partial years are marked.

¥76.00

2025 complete year+65.2% since 2021

2026 partial: ¥39.00

* Partial calendar year in the available dividend history.

Corporate action history

DividendUpcoming

Ex-dividend Sep 29, 2026

¥40.00

Semi-Annual

Record Sep 30, 2026 · Payment Sep 29, 2026

DividendUpcoming

Ex-dividend Mar 30, 2027

¥40.00

Semi-Annual

Record Mar 31, 2027 · Payment Mar 30, 2027

Dividend

Ex-dividend Mar 30, 2026

¥39.00

Semi-Annual

Record Mar 31, 2026 · Payment Jun 3, 2026

Dividend

Ex-dividend Sep 29, 2025

¥39.00

Semi-Annual

Record Sep 30, 2025 · Payment Dec 1, 2025

Dividend

Ex-dividend Mar 28, 2025

¥37.00

Semi-Annual

Record Mar 31, 2025 · Payment Jun 3, 2025

Dividend

Ex-dividend Sep 27, 2024

¥37.00

Semi-Annual

Record Sep 30, 2024 · Payment Dec 2, 2024

4503.T peers

ETFs holding 4503.T

Funds reporting this stock among their holdings, ordered by reported position size.

Continue in GoAI

Research 4503.T

research.disclaimer