
Astellas Pharma Inc.
4503.TJPXHealthcareDrug Manufacturers - General
Latest quote
¥2,406.5
+¥19.50 · +0.82%
4503.T company overview
Regular session · JST · Market data may be delayed.
Company profile
Company websiteAstellas Pharma Inc., a venerable Japanese pharmaceutical enterprise established in 1923 and headquartered in Tokyo, operates globally in the research, development, manufacturing, and commercialization of a diverse range of medications. Its extensive product lineup addresses critical health needs, including various oncology treatments such as XTANDI for prostate cancer, XOSPATA, an FLT3 inhibitor for specific relapsed or refractory acute myeloid leukemia, and PADCEV for advanced urothelial cancer. For urological conditions, Astellas offers Betanis/Myrbetriq/BETMIGA to manage symptoms of overactive bladder, mirabegron for neurogenic detrusor overactivity in children, and Vesicare for OAB. Other notable pharmaceuticals include Eligard for prostate cancer, Harnal/Omnic for benign prostatic hyperplasia, Evrenzo for anemia associated with chronic kidney disease, and the immunosuppressants Prograf/Advagraf/Graceptor/ASTAGRAF, vital for preventing organ transplant rejection. The company also markets Funguard/MYCAMINE, an antifungal agent. Astellas actively fosters innovation through numerous strategic collaborations and partnerships. These include clinical trial agreements with pharmaceutical giants like Merck & Co., Inc. and CytomX Therapeutics, Inc. Demonstrating a broader approach to health, they collaborate with BANDAI NAMCO Entertainment Inc. on developing a smartphone exercise support application. In the realm of scientific discovery, Astellas maintains a research alliance with Harvard University for joint therapeutic and technological advancements. Further research initiatives involve Actinium Pharmaceuticals, Inc. to advance targeted radiotherapies leveraging their Antibody Warhead Enabling platform, an agreement with Zenith Epigenetics Ltd. to evaluate ZEN-3694, and a collaboration with Cytokinetics, Incorporated. A significant strategic alliance and license agreement exist with Minovia Therapeutics Ltd. to research, develop, and commercialize cell therapies for mitochondrial dysfunction.
- Industry
- Drug Manufacturers - General
- Sector
- Healthcare
- Headquarters
- JP
- CEO
- Naoki Okamura
- Listed since
- May 15, 1949
- Employees
- 14,099
Market position
- Volume
- 4.26M
- 0.65× average
- Average volume
- 6.54M
- Average daily volume
- Market cap
- 4.31T JPY
- Beta
- 0.08
- Market reference 1
Financials
Financial snapshot
Latest / TTMValuation & yield
- Enterprise value
- 4.8T JPY
- P/E (TTM)
- 11.81×
- P/B (TTM)
- 2.22×
- P/S (TTM)
- 1.9×
- EV / EBITDA
- 8.19×
- Earnings yield
- 6.46%
- Free cash flow yield
- 11.27%
- Dividend yield
- 3.24%
Profitability & efficiency
- Gross margin
- 74.71%
- Operating margin
- 21.81%
- Net margin
- 16.04%
- Return on equity
- 15.92%
- Return on assets
- 8.17%
- Return on invested capital
- 12.52%
Financial health
- Debt / equity
- 0.3×
- Current ratio
- 1.17×
- Altman Z-score
- 2.96
- Piotroski F-score
- 8 of 9
Financial statements
Margin trends
Profitability as a percentage of reported revenue.
Income trends
Revenue
Operating income
Net income
| Metric (JPY) | FY2026 | FY2025 | FY2024 | FY2023 | FY2022 |
|---|---|---|---|---|---|
| Revenue | 2.14T JPY | 1.91T JPY | 1.6T JPY | 1.52T JPY | 1.3T JPY |
| Cost of goods sold | 544.41B JPY | 349.21B JPY | 292.49B JPY | 288.35B JPY | 253.01B JPY |
| Gross profit | 1.59T JPY | 1.56T JPY | 1.31T JPY | 1.23T JPY | 1.04T JPY |
| Research and development | 314.83B JPY | 327.7B JPY | 294.2B JPY | 276.1B JPY | 246B JPY |
| Selling, general, and administrative | 860.31B JPY | 843.03B JPY | 740.11B JPY | 630.27B JPY | 548.84B JPY |
| Operating expenses | 1.18T JPY | 1.31T JPY | 1.13T JPY | 944.84B JPY | 823.13B JPY |
| Interest income | 8.03B JPY | 7.87B JPY | 8.77B JPY | 8.11B JPY | 6.15B JPY |
| Interest expense | 14.07B JPY | 17.68B JPY | 9.37B JPY | 8.78B JPY | 4.95B JPY |
| Depreciation and amortization | 194.59B JPY | 199.13B JPY | 157.84B JPY | 105.74B JPY | 79.68B JPY |
| Operating income | 419.7B JPY | 255.67B JPY | 178.07B JPY | 285.43B JPY | 220.02B JPY |
| Net income | 291.54B JPY | 50.75B JPY | 17.05B JPY | 98.71B JPY | 124.09B JPY |
Company facts updated Aug 24, 2026.
Earnings
- EPS beat rate
- 64%
- 7 beats, 4 misses, 0 met estimates
- Average EPS surprise
- -48.80%
- 11 comparable reports
- Latest EPS result
- 79.15
- Estimate 52.62 · Beat by 50.42%
EPS: actual versus estimate
Recent quarterly results
Revenue: actual versus estimate
Recent quarterly results
Corporate actions
Annual dividends per share
Cash distributions grouped by calendar year; partial years are marked.
¥76.00
2025 complete year+65.2% since 2021
2026 partial: ¥39.00
¥46.00
2,021
¥55.00
2,022
¥65.00
2,023
¥72.00
2,024
¥76.00
2,025
¥39.00
2,026*
* Partial calendar year in the available dividend history.
Corporate action history
| Action | Ex-dividend date | Details | Record date | Payment date |
|---|---|---|---|---|
DividendUpcoming | Sep 29, 2026 | ¥40.00Semi-Annual | Sep 30, 2026 | Sep 29, 2026 |
DividendUpcoming | Mar 30, 2027 | ¥40.00Semi-Annual | Mar 31, 2027 | Mar 30, 2027 |
Dividend | Mar 30, 2026 | ¥39.00Semi-Annual | Mar 31, 2026 | Jun 3, 2026 |
Dividend | Sep 29, 2025 | ¥39.00Semi-Annual | Sep 30, 2025 | Dec 1, 2025 |
Dividend | Mar 28, 2025 | ¥37.00Semi-Annual | Mar 31, 2025 | Jun 3, 2025 |
Dividend | Sep 27, 2024 | ¥37.00Semi-Annual | Sep 30, 2024 | Dec 2, 2024 |
Ex-dividend Sep 29, 2026
¥40.00
Semi-Annual
Record Sep 30, 2026 · Payment Sep 29, 2026
Ex-dividend Mar 30, 2027
¥40.00
Semi-Annual
Record Mar 31, 2027 · Payment Mar 30, 2027
Ex-dividend Mar 30, 2026
¥39.00
Semi-Annual
Record Mar 31, 2026 · Payment Jun 3, 2026
Ex-dividend Sep 29, 2025
¥39.00
Semi-Annual
Record Sep 30, 2025 · Payment Dec 1, 2025
Ex-dividend Mar 28, 2025
¥37.00
Semi-Annual
Record Mar 31, 2025 · Payment Jun 3, 2025
Ex-dividend Sep 27, 2024
¥37.00
Semi-Annual
Record Sep 30, 2024 · Payment Dec 2, 2024
4503.T peers
ETFs holding 4503.T
Funds reporting this stock among their holdings, ordered by reported position size.
iShares Core Nikkei 225 ETF1329.T12.79B0.60%2.12T JPY0.05%¥6,789-0.77%
iShares Core TOPIX ETF1475.T10.69B0.37%2.89T JPY0.05%¥417.7-0.07%
iShares JPX-Nikkei 400 ETF1364.T3.14B0.53%592.34B JPY0.05%¥3,7610.00%
Vanguard Total International Stock ETFVXUS362.86M0.05%646.2B USD0.05%$87.71+0.78%
Vanguard FTSE Developed Markets ETFVEA241.55M0.08%315B USD0.03%$73.42+0.80%
iShares Core MSCI EAFE ETFIEFA196.26M0.10%195.14B USD0.07%$100.85+0.86%
iShares MSCI Japan ETFEWJ112.77M0.50%22.49B USD0.49%$95.18+0.97%
iShares MSCI EAFE ETFEFA95.11M0.12%79.94B USD0.32%$108.24+0.83%
iShares Core Nikkei 225 ETF1329.T- Market value
- 12.79B
- Weight
- 0.60%
- AUM
- 2.12T JPY
- Expense ratio
- 0.05%
- Price / 1D
- ¥6,789-0.77%
iShares Core TOPIX ETF1475.T- Market value
- 10.69B
- Weight
- 0.37%
- AUM
- 2.89T JPY
- Expense ratio
- 0.05%
- Price / 1D
- ¥417.7-0.07%
iShares JPX-Nikkei 400 ETF1364.T- Market value
- 3.14B
- Weight
- 0.53%
- AUM
- 592.34B JPY
- Expense ratio
- 0.05%
- Price / 1D
- ¥3,7610.00%
Vanguard Total International Stock ETFVXUS- Market value
- 362.86M
- Weight
- 0.05%
- AUM
- 646.2B USD
- Expense ratio
- 0.05%
- Price / 1D
- $87.71+0.78%
Vanguard FTSE Developed Markets ETFVEA- Market value
- 241.55M
- Weight
- 0.08%
- AUM
- 315B USD
- Expense ratio
- 0.03%
- Price / 1D
- $73.42+0.80%
iShares Core MSCI EAFE ETFIEFA- Market value
- 196.26M
- Weight
- 0.10%
- AUM
- 195.14B USD
- Expense ratio
- 0.07%
- Price / 1D
- $100.85+0.86%
iShares MSCI Japan ETFEWJ- Market value
- 112.77M
- Weight
- 0.50%
- AUM
- 22.49B USD
- Expense ratio
- 0.49%
- Price / 1D
- $95.18+0.97%
iShares MSCI EAFE ETFEFA- Market value
- 95.11M
- Weight
- 0.12%
- AUM
- 79.94B USD
- Expense ratio
- 0.32%
- Price / 1D
- $108.24+0.83%
Continue in GoAI
Research 4503.Tresearch.disclaimer





