
Otsuka Holdings Co., Ltd.
4578.TJPXHealthcareDrug Manufacturers - General
Latest quote
¥12,210
+¥15.00 · +0.12%
4578.T company overview
Regular session · JST · Market data may be delayed.
Company profile
Company websiteOtsuka Holdings Co., Ltd. engages in the pharmaceuticals, nutraceuticals, consumer products, and other businesses worldwide. It develops pharmaceutical products in the fields of psychiatry, neurology, oncology, cardiovascular and renal system, autoimmune space digestive system, ophthalmology, and diagnostics, as well as intravenous solutions and medical devices. It also provides clinical testing, medical equipment and tools, food products, cosmetics, functional food products, chemical products, soft drinks, beverages, analytical and measurement equipment, nutritional products, vehicle headlight testers, synthetic resin molded products, paper products, quasi-drugs, household products, and packaging materials and electronic parts. In addition, it offers IT solutions; adhesive tapes; flaky titanate and compounds; infusion and clinical nutrition products; hydrazine; plant-based food products; reinsurance underwriting services; wine; stable isotopes; food supplements; software and services for management of mental healthcare systems; anticancer drugs; terracess; bio-pesticides; dietetic food products; spring and mineral water; and polyolefin foams. Further, it engages in the warehousing and transport, medical device operational management, shared service, environmental health management, and venture capital and incubation businesses; rental of medical devices and related products; purchase and sale of agricultural products; import and export trading business; tuberculosis research and development activities; rental of space and office businesses; manufacturing and development of xenotransplantation products; and processing and marketing of functional films, as well as planning, design, production, and construction of ceramic boards and arts, ceramic walls, reliefs, terracotta, ceramic OT and portraits, and ceramic sign boards; and operation of travel agency, and Hotel Ridge and California Table. The company was founded in 1921 and is headquartered in Chiyoda, Japan.
- Industry
- Drug Manufacturers - General
- Sector
- Healthcare
- Headquarters
- JP
- CEO
- Makoto Inoue
- Listed since
- Dec 15, 2010
- Employees
- 37,758
Market position
Day range
Current ¥12,210
52-week range
Current ¥12,210
- Open
- ¥12,295
- Previous close
- ¥12,195
- Volume
- 614.4K
- 0.48× average
- Average volume
- 1.28M
- Average daily volume
- Market cap
- 6.42T JPY
- Beta
- -0.05
- Market reference 1
- 50-day average
- ¥11,295.9
- +8.09% above average
- 200-day average
- ¥10,350.93
- +17.96% above average
Financials
Financial snapshot
Latest / TTMValuation & yield
- Enterprise value
- 4.4T JPY
- P/E (TTM)
- 15.89×
- P/B (TTM)
- 1.98×
- P/S (TTM)
- 2.45×
- EV / EBITDA
- 7.19×
- Earnings yield
- 7.72%
- Free cash flow yield
- 6.71%
- Dividend yield
- 1.39%
Profitability & efficiency
- Gross margin
- 71.78%
- Operating margin
- 17.26%
- Net margin
- 15.46%
- Return on equity
- 11.97%
- Return on assets
- 8.65%
- Return on invested capital
- 9.20%
Financial health
- Debt / equity
- 0.06×
- Current ratio
- 2.17×
Financial statements
Margin trends
Profitability as a percentage of reported revenue.
Income trends
Revenue
Operating income
Net income
| Metric (JPY) | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 |
|---|---|---|---|---|---|
| Revenue | 2.47T JPY | 2.33T JPY | 2.02T JPY | 1.74T JPY | 1.5T JPY |
| Cost of goods sold | 699.12B JPY | 660.43B JPY | 611.22B JPY | 569.5B JPY | 495.03B JPY |
| Gross profit | 1.77T JPY | 1.67T JPY | 1.41T JPY | 1.17T JPY | 1T JPY |
| Research and development | 352.84B JPY | 314.23B JPY | 307.8B JPY | 275.23B JPY | 232.3B JPY |
| Selling, general, and administrative | 1T JPY | 958.35B JPY | 807.36B JPY | 724.13B JPY | 622.33B JPY |
| Operating expenses | 1.36T JPY | 1.27T JPY | 1.27T JPY | 1.02T JPY | 854.63B JPY |
| Interest income | 15.7B JPY | 21.08B JPY | 9.57B JPY | 28.69B JPY | 13.98B JPY |
| Interest expense | 27.03B JPY | 8.79B JPY | 6.52B JPY | 6.06B JPY | 4.84B JPY |
| Depreciation and amortization | 116.17B JPY | 107.98B JPY | 93.7B JPY | 93.76B JPY | 84.86B JPY |
| Operating income | 412.43B JPY | 396.85B JPY | 139.61B JPY | 150.32B JPY | 148.62B JPY |
| Net income | 363.15B JPY | 343.12B JPY | 121.62B JPY | 133.91B JPY | 125.46B JPY |
Company facts updated Aug 24, 2026.
4578.T peers
ETFs holding 4578.T
Funds reporting this stock among their holdings, ordered by reported position size.
iShares Core TOPIX ETF1475.T15.13B0.52%2.89T JPY0.05%¥417.7-0.07%
iShares Core Nikkei 225 ETF1329.T13.07B0.62%2.12T JPY0.05%¥6,789-0.77%
iShares JPX-Nikkei 400 ETF1364.T4.44B0.75%592.34B JPY0.05%¥3,7610.00%
Vanguard Total International Stock ETFVXUS452.59M0.07%646.2B USD0.05%$87.71+0.78%
Vanguard FTSE Developed Markets ETFVEA301.45M0.09%315B USD0.03%$73.42+0.80%
iShares Core MSCI EAFE ETFIEFA247.98M0.13%195.14B USD0.07%$100.85+0.86%
iShares MSCI Japan ETFEWJ143.54M0.64%22.49B USD0.49%$95.18+0.97%
JPMorgan BetaBuilders Japan ETFBBJP123.53M0.65%18.96B USD0.19%$76.87+0.97%
iShares Core TOPIX ETF1475.T- Market value
- 15.13B
- Weight
- 0.52%
- AUM
- 2.89T JPY
- Expense ratio
- 0.05%
- Price / 1D
- ¥417.7-0.07%
iShares Core Nikkei 225 ETF1329.T- Market value
- 13.07B
- Weight
- 0.62%
- AUM
- 2.12T JPY
- Expense ratio
- 0.05%
- Price / 1D
- ¥6,789-0.77%
iShares JPX-Nikkei 400 ETF1364.T- Market value
- 4.44B
- Weight
- 0.75%
- AUM
- 592.34B JPY
- Expense ratio
- 0.05%
- Price / 1D
- ¥3,7610.00%
Vanguard Total International Stock ETFVXUS- Market value
- 452.59M
- Weight
- 0.07%
- AUM
- 646.2B USD
- Expense ratio
- 0.05%
- Price / 1D
- $87.71+0.78%
Vanguard FTSE Developed Markets ETFVEA- Market value
- 301.45M
- Weight
- 0.09%
- AUM
- 315B USD
- Expense ratio
- 0.03%
- Price / 1D
- $73.42+0.80%
iShares Core MSCI EAFE ETFIEFA- Market value
- 247.98M
- Weight
- 0.13%
- AUM
- 195.14B USD
- Expense ratio
- 0.07%
- Price / 1D
- $100.85+0.86%
iShares MSCI Japan ETFEWJ- Market value
- 143.54M
- Weight
- 0.64%
- AUM
- 22.49B USD
- Expense ratio
- 0.49%
- Price / 1D
- $95.18+0.97%
JPMorgan BetaBuilders Japan ETFBBJP- Market value
- 123.53M
- Weight
- 0.65%
- AUM
- 18.96B USD
- Expense ratio
- 0.19%
- Price / 1D
- $76.87+0.97%
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