MediciNova, Inc. logo

MediciNova, Inc.

MNOV

NASDAQHealthcareBiotechnology

Previous close

$1.39

+$0.03 · +2.21%

Aug 21, 4:00 PM ET

MNOV company overview

Regular session · ET · Market data may be delayed.

GoAI snapshot

AI-powered factor overview

Jul 10, 2026

GoAI score

Sell

Trim exposure — unfavorable risk-reward

Valuation

26

Expensive

Momentum

40

Weakening

Sentiment

56

Mixed

Risk resilience

49

Elevated Risk

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Company profile

Company website

MediciNova, Inc. is a biopharmaceutical firm dedicated to discovering and advancing innovative small molecule therapies for severe illnesses where current treatments are insufficient within the United States. Its robust development pipeline features MN-166 (ibudilast), an oral agent with both anti-inflammatory and neuroprotective properties, currently being investigated for a range of neurological conditions. These include primary and secondary progressive multiple sclerosis, amyotrophic lateral sclerosis, chemotherapy-induced peripheral neuropathy, degenerative cervical myelopathy, glioblastoma, and various forms of substance dependence and addiction. The company's portfolio also comprises MN-221 (bedoradrine), a selective beta-2-adrenergic receptor agonist aimed at treating acute asthma attacks; MN-001 (tipelukast), an orally available small molecule designed for fibrotic disorders like nonalcoholic steatohepatitis and idiopathic pulmonary fibrosis; and MN-029 (denibulin), a tubulin binding agent intended for solid tumor oncology. MediciNova has established strategic partnerships with companies such as Kissei Pharmaceutical Co., Ltd., Kyorin Pharmaceutical Co., Ltd., Angiogene Pharmaceuticals Ltd., and Meiji Seika Kaisha Ltd. Established in 2000, the company's headquarters are situated in La Jolla, California.

Industry
Biotechnology
Sector
Healthcare
Headquarters
US
CEO
Yuichi Iwaki
Listed since
Dec 8, 2006
Employees
6

Market position

Day range

Current $1.39

52-week range

Current $1.39

Open
$1.37
Previous close
$1.36
Volume
26.8K
0.67× average
Average volume
39.81K
Average daily volume
Market cap
68.42M USD
Beta
0.62
Market reference 1
50-day average
$1.3414
+3.62% above average
200-day average
$1.4275
-2.63% below average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
33.66M USD
P/E (TTM)
-6.4×
P/B (TTM)
1.84×
P/S (TTM)
74.33×
EV / EBITDA
-2.81×
Earnings yield
-18.67%
Free cash flow yield
-15.27%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
42.39%
Operating margin
-1287.41%
Net margin
-1168.20%
Return on equity
-28.85%
Return on assets
-26.31%
Return on invested capital
-31.63%

Financial health

Debt / equity
Current ratio
8.16×

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends434%-903%-2240%-3577%Gross margin, FY2021: 100.00%Gross margin, FY2023: 100.00%Gross margin, FY2025: 7.58%Operating margin, FY2021: -253.02%Operating margin, FY2023: -990.03%Operating margin, FY2025: -3242.47%Net margin, FY2021: -251.00%Net margin, FY2023: -857.15%Net margin, FY2025: -2928.78%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2021 100.00%. Gross margin FY2023 100.00%. Gross margin FY2025 7.58%. Operating margin FY2021 -253.02%. Operating margin FY2023 -990.03%. Operating margin FY2025 -3242.47%. Net margin FY2021 -251.00%. Net margin FY2023 -857.15%. Net margin FY2025 -2928.78%.

Income trends

Revenue

409.66K USD-59.03%

Operating income

−13.28M USD-4.79%

Net income

−12M USD-8.58%
Income trends across reported periods5.9M USD−1.56M USD−9.03M USD−16.5M USDRevenue, FY2021: 4.04M USDRevenue, FY2023: 1M USDRevenue, FY2025: 409.66K USDOperating income, FY2021: −10.22M USDOperating income, FY2022: −14.63M USDOperating income, FY2023: −9.9M USDOperating income, FY2024: −12.68M USDOperating income, FY2025: −13.28M USDNet income, FY2021: −10.13M USDNet income, FY2022: −14.07M USDNet income, FY2023: −8.57M USDNet income, FY2024: −11.05M USDNet income, FY2025: −12M USDFY2021FY2022FY2023FY2024FY2025
Revenue FY2021 4.04M USD. Revenue FY2023 1M USD. Revenue FY2025 409.66K USD. Operating income FY2021 −10.22M USD. Operating income FY2022 −14.63M USD. Operating income FY2023 −9.9M USD. Operating income FY2024 −12.68M USD. Operating income FY2025 −13.28M USD. Net income FY2021 −10.13M USD. Net income FY2022 −14.07M USD. Net income FY2023 −8.57M USD. Net income FY2024 −11.05M USD. Net income FY2025 −12M USD.
Metric (USD)FY2025FY2024FY2023FY2022FY2021
Revenue409.66K USD1M USD4.04M USD
Cost of goods sold378.61K USD
Gross profit31.05K USD1M USD4.04M USD
Research and development7.16M USD7.2M USD5.66M USD9.14M USD8.1M USD
Selling, general, and administrative6.16M USD5.48M USD5.24M USD5.48M USD5.72M USD
Operating expenses13.31M USD12.68M USD10.9M USD14.63M USD14.25M USD
Interest income1.3M USD1.67M USD1.83M USD809.67K USD143.63K USD
Depreciation and amortization20.1K USD21.08K USD20.3K USD17.71K USD26.15K USD
Operating income−13.28M USD−12.68M USD−9.9M USD−14.63M USD−10.22M USD
Net income−12M USD−11.05M USD−8.57M USD−14.07M USD−10.13M USD

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
64%
7 beats, 1 miss, 3 met estimates
Average EPS surprise
+19.44%
11 comparable reports
Latest EPS result
-0.05
Estimate -0.06 · Beat by 21.05%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates-0.04-0.09-0.13-0.18Q1 '25MetQ2 '25BeatQ3 '25MetQ4 '25BeatQ1 '26BeatQ2 '26BeatQ3 '26BeatQ4 '26Estimate
Q1 2025, reported Feb 19, 2025: actual -0.06, estimate -0.06, surprise 0.00%, Met estimate. Q2 2025, reported May 14, 2025: actual -0.06, estimate -0.14, surprise +57.14%, Beat. Q3 2025, reported Aug 14, 2025: actual -0.07, estimate -0.07, surprise 0.00%, Met estimate. Q4 2025, reported Nov 13, 2025: actual -0.06, estimate -0.08, surprise +25.00%, Beat. Q1 2026, reported Feb 20, 2026: actual -0.05, estimate -0.095, surprise +47.37%, Beat. Q2 2026, reported May 15, 2026: actual -0.05, estimate -0.06, surprise +16.67%, Beat. Q3 2026, reported Aug 13, 2026: actual -0.05, estimate -0.063, surprise +21.05%, Beat. Q4 2026, reported Nov 12, 2026: actual —, estimate -0.06, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates490.8K344.63K198.45K52.28KQ3 '25BeatQ4 '25MissQ1 '26MissQ2 '26MetQ3 '26BeatQ4 '26Estimate
Q3 2025, reported Aug 14, 2025: actual 134.6K USD, estimate 123.32K USD, surprise +9.15%, Beat. Q4 2025, reported Nov 13, 2025: actual 61.5K USD, estimate 151.74K USD, surprise -59.47%, Miss. Q1 2026, reported Feb 20, 2026: actual 151K USD, estimate 151.74K USD, surprise -0.49%, Miss. Q2 2026, reported May 15, 2026: actual 186.98K USD, estimate 186.98K USD, surprise 0.00%, Met estimate. Q3 2026, reported Aug 13, 2026: actual 459K USD, estimate 75K USD, surprise +512.00%, Beat. Q4 2026, reported Nov 12, 2026: actual —, estimate 75K USD, surprise —, Comparison unavailable.

Analyst ratings

Third-party consensus; not a GoAI recommendation.

Rating distribution

4 ratings

Limited analyst sample: 4 ratings. Interpret the distribution with caution.

Strong buy00%
Buy4100%
Hold00%
Sell00%
Strong sell00%

Recent analyst actions

2 institutions
B. Riley SecuritiesmaintainBuy

MNOV news

MNOV peers

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