Ono Pharmaceutical Co., Ltd. logo

Ono Pharmaceutical Co., Ltd.

4528.T

JPXHealthcareDrug Manufacturers - General

Latest quote

¥2,441

−¥7.00 · -0.29%

Aug 24, 1:22 PM JST

4528.T company overview

Regular session · JST · Market data may be delayed.

Company profile

Company website

Ono Pharmaceutical Co., Ltd., along with its affiliated companies, is engaged in the global development, manufacturing, procurement, and sale of a diverse range of pharmaceutical products and diagnostic tools. Its diverse oncology portfolio includes OPDIVO intravenous infusions, KYPROLIS for injection, MEKTOVI, VELEXBRU, and ADLUMIZ tablets, along with BRAFTOVI capsules, all prescribed for various malignant tumors. It also provides EMEND capsules and PROEMEND intravenous injections to alleviate chemotherapy-induced nausea and vomiting, and DEMSER capsules for managing symptoms in pheochromocytoma patients. Beyond oncology, the company's offerings span multiple therapeutic areas. For metabolic disorders, it supplies GLACTIV and FORXIGA tablets for type 2 diabetes. Cardiovascular health is supported by ONOACT injections for tachyarrhythmia, CORALAN for chronic heart failure, and OPALMON tablets addressing peripheral circulatory disorders. Autoimmune conditions like rheumatoid arthritis are treated with ORENCIA injections. Neurological therapies include RIVASTACH patches for Alzheimer's disease and ONGENTYS tablets for Parkinson's disease. Other notable products are PARSABIV intravenous injections for dialysis patients, STAYBLA tablets for overactive bladder, ONON capsules and dry syrups for bronchial asthma and allergic rhinitis, and RECALBON tablets for osteoporosis, with JOYCLU intra-articular injection available to improve joint function. Moreover, the company is heavily invested in research and development, with a pipeline targeting a wide array of diseases. This includes various malignancies such as esophageal, urothelial, Hodgkin's lymphoma, ovarian, bladder, prostate, hepatocellular, pancreatic, biliary tract, gastric, thyroid, colorectal, melanoma, acute myeloid leukemia, non-small cell lung cancer, and virus-positive/negative solid tumors, as well as primary central nervous system lymphoma. Beyond cancer, its developmental efforts extend to myelodysplastic syndrome, polymyositis/dermatomyositis, tachyarrhythmia, pemphigus, generalized scleroderma, enthesopathy, diabetic polyneuropathy, neurodegenerative and autoimmune disorders, narcolepsy, and thrombosis. Established in 1717, the company maintains its corporate headquarters in Osaka, Japan.

Industry
Drug Manufacturers - General
Sector
Healthcare
Headquarters
JP
CEO
Gyo Sagara
Listed since
Jan 4, 2001
Employees
4,206

Market position

Day range

Current ¥2,441

52-week range

Current ¥2,441

Open
¥2,458
Previous close
¥2,448
Volume
577.7K
0.34× average
Average volume
1.72M
Average daily volume
Market cap
1.15T JPY
Beta
0.13
Market reference 1
50-day average
¥2,383.11
+2.43% above average
200-day average
¥2,341.27
+4.26% above average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
1.06T JPY
P/E (TTM)
15.04×
P/B (TTM)
1.32×
P/S (TTM)
2.27×
EV / EBITDA
7.94×
Earnings yield
5.91%
Free cash flow yield
11.09%
Dividend yield
3.28%

Profitability & efficiency

Gross margin
73.56%
Operating margin
22.07%
Net margin
15.13%
Return on equity
8.20%
Return on assets
6.31%
Return on invested capital
7.95%

Financial health

Debt / equity
0.14×
Current ratio
2.86×
Altman Z-score
5.46
Piotroski F-score
7 of 9

Earnings

EPS beat rate
36%
4 beats, 7 misses, 0 met estimates
Average EPS surprise
-26.77%
11 comparable reports
Latest EPS result
51.4
Estimate 33.74 · Beat by 52.34%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates67.4538.319.17-19.97Q1 '25MissQ2 '25MissQ3 '25MissQ4 '25BeatQ1 '26BeatQ2 '26MissQ3 '26BeatQ4 '26Estimate
Q1 2025, reported Feb 3, 2025: actual 31.83, estimate 52.05, surprise -38.85%, Miss. Q2 2025, reported May 8, 2025: actual -13.94, estimate 13.83, surprise -200.80%, Miss. Q3 2025, reported Aug 1, 2025: actual 37.62, estimate 49.47, surprise -23.95%, Miss. Q4 2025, reported Oct 30, 2025: actual 47.71, estimate 40.65, surprise +17.37%, Beat. Q1 2026, reported Feb 2, 2026: actual 61.42, estimate 45.26, surprise +35.70%, Beat. Q2 2026, reported May 8, 2026: actual 1.74, estimate 8.25, surprise -78.91%, Miss. Q3 2026, reported Jul 31, 2026: actual 51.4, estimate 33.74, surprise +52.34%, Beat. Q4 2026, reported Nov 2, 2026: actual —, estimate 39.16, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates145.5B131.99B118.48B104.97BQ1 '25BeatQ2 '25MissQ3 '25BeatQ4 '25BeatQ1 '26BeatQ2 '26BeatQ3 '26BeatQ4 '26Estimate
Q1 2025, reported Feb 3, 2025: actual 134.22B JPY, estimate 131.11B JPY, surprise +2.38%, Beat. Q2 2025, reported May 8, 2025: actual 112.31B JPY, estimate 120.82B JPY, surprise -7.04%, Miss. Q3 2025, reported Aug 1, 2025: actual 127.54B JPY, estimate 119.22B JPY, surprise +6.97%, Beat. Q4 2025, reported Oct 30, 2025: actual 129.6B JPY, estimate 122.12B JPY, surprise +6.12%, Beat. Q1 2026, reported Feb 2, 2026: actual 139.9B JPY, estimate 130.24B JPY, surprise +7.42%, Beat. Q2 2026, reported May 8, 2026: actual 118.75B JPY, estimate 112.22B JPY, surprise +5.82%, Beat. Q3 2026, reported Jul 31, 2026: actual 116.16B JPY, estimate 110.57B JPY, surprise +5.06%, Beat. Q4 2026, reported Nov 2, 2026: actual —, estimate 112.28B JPY, surprise —, Comparison unavailable.

Corporate actions

Annual dividends per share

Cash distributions grouped by calendar year; partial years are marked.

¥80.00

2025 complete year+58.4% since 2021

2026 partial: ¥40.00

* Partial calendar year in the available dividend history.

Corporate action history

DividendUpcoming

Ex-dividend Sep 29, 2026

¥40.00

Semi-Annual

Record Sep 30, 2026 · Payment Sep 29, 2026

DividendUpcoming

Ex-dividend Mar 30, 2027

¥40.00

Semi-Annual

Record Mar 31, 2027 · Payment Mar 30, 2027

Dividend

Ex-dividend Mar 30, 2026

¥40.00

Semi-Annual

Record Mar 31, 2026 · Payment Jun 19, 2026

Dividend

Ex-dividend Sep 29, 2025

¥40.00

Semi-Annual

Record Sep 30, 2025 · Payment Dec 1, 2025

Dividend

Ex-dividend Mar 28, 2025

¥40.00

Semi-Annual

Record Mar 31, 2025 · Payment Jun 20, 2025

Dividend

Ex-dividend Sep 27, 2024

¥40.00

Semi-Annual

Record Sep 30, 2024 · Payment Dec 2, 2024

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