
Santen Pharmaceutical Co., Ltd.
4536.TJPXHealthcareDrug Manufacturers - General
Latest quote
¥1,874.5
−¥5.00 · -0.27%
4536.T company overview
Regular session · JST · Market data may be delayed.
Company profile
Company websiteSanten Pharmaceutical Co., Ltd. is a global enterprise engaged in the research, development, manufacturing, and marketing of both pharmaceutical products and medical devices. The company's primary focus lies in ophthalmic solutions, addressing a variety of eye conditions. Its pipeline for glaucoma and ocular hypertension includes several key assets: DE-111, currently in Phase III clinical trials; DE-117, available for sale in Japan; DE-126, progressing through Phase IIb trials; DE-128, which is on the market in Europe and undergoing Phase II/III trials in the United States; and DE-130A, also in Phase III development. Beyond glaucoma, Santen's offerings extend to other ocular ailments. It provides DE-114A for allergic conjunctivitis and DE-076C for vernal keratoconjunctivitis. Furthermore, DE-109 is in Phase III clinical trials for the treatment of uveitis. The company is also active in addressing myopia with DE-127, currently in Phase II/III trials in Japan and Phase III in other Asian markets, alongside STN1013400, which is in Phase I trials. For dry eye, Santen offers DE-089C, which has successfully concluded its Phase III clinical trials. In addition to its prescription portfolio, the company produces and sells various over-the-counter (OTC) pharmaceutical products. Founded in 1890 under the name Santendo Pharmaceutical Co., Ltd., the company rebranded to its current name, Santen Pharmaceutical Co., Ltd., in 1958. It is headquartered in Osaka, Japan.
- Industry
- Drug Manufacturers - General
- Sector
- Healthcare
- Headquarters
- JP
- CEO
- Takeshi Ito
- Listed since
- Jan 4, 2001
- Employees
- 3,968
Market position
Day range
Current ¥1,874.5
52-week range
Current ¥1,874.5
- Open
- ¥1,890
- Previous close
- ¥1,879.5
- Volume
- 871.9K
- 0.75× average
- Average volume
- 1.16M
- Average daily volume
- Market cap
- 603B JPY
- Beta
- 0.23
- Market reference 1
- 50-day average
- ¥2,005.36
- -6.53% below average
- 200-day average
- ¥1,782.48
- +5.16% above average
Financials
Financial snapshot
Latest / TTMValuation & yield
- Enterprise value
- 538.85B JPY
- P/E (TTM)
- 15.74×
- P/B (TTM)
- 2.01×
- P/S (TTM)
- 2.07×
- EV / EBITDA
- 7.95×
- Earnings yield
- 6.39%
- Free cash flow yield
- 6.27%
- Dividend yield
- 2.03%
Profitability & efficiency
- Gross margin
- 56.10%
- Operating margin
- 15.67%
- Net margin
- 13.25%
- Return on equity
- 12.58%
- Return on assets
- 8.83%
- Return on invested capital
- 10.57%
Financial health
- Debt / equity
- 0.1×
- Current ratio
- 2.6×
- Altman Z-score
- 5.37
- Piotroski F-score
- 8 of 9
Financial statements
Margin trends
Profitability as a percentage of reported revenue.
Income trends
Revenue
Operating income
Net income
| Metric (JPY) | FY2026 | FY2025 | FY2024 | FY2023 | FY2022 |
|---|---|---|---|---|---|
| Revenue | 291.62B JPY | 300B JPY | 301.97B JPY | 279.04B JPY | 266.26B JPY |
| Cost of goods sold | 130.65B JPY | 136.8B JPY | 138.09B JPY | 122.47B JPY | 119.41B JPY |
| Gross profit | 160.97B JPY | 163.21B JPY | 163.88B JPY | 156.57B JPY | 146.85B JPY |
| Research and development | 26.19B JPY | 23.47B JPY | 24.7B JPY | 28.3B JPY | 26.38B JPY |
| Selling, general, and administrative | 89.57B JPY | 83.51B JPY | 87.27B JPY | 96.26B JPY | 84.5B JPY |
| Operating expenses | 115.76B JPY | 106.98B JPY | 111.97B JPY | 124.55B JPY | 110.88B JPY |
| Interest income | 1.64B JPY | 1.05B JPY | 619M JPY | 469M JPY | 402M JPY |
| Interest expense | 1.99B JPY | 1.08B JPY | 831M JPY | 486M JPY | 250M JPY |
| Depreciation and amortization | 18.36B JPY | 17.95B JPY | 18.18B JPY | 17.25B JPY | 17.06B JPY |
| Operating income | 45.22B JPY | 56.23B JPY | 51.9B JPY | 32.02B JPY | 35.98B JPY |
| Net income | 37.37B JPY | 36.26B JPY | 26.64B JPY | −14.95B JPY | 27.22B JPY |
Company facts updated Aug 24, 2026.
Earnings
- EPS beat rate
- 73%
- 8 beats, 3 misses, 0 met estimates
- Average EPS surprise
- +5.73%
- 11 comparable reports
- Latest EPS result
- 22.38
- Estimate 21.27 · Beat by 5.22%
EPS: actual versus estimate
Recent quarterly results
Revenue: actual versus estimate
Recent quarterly results
Corporate actions
Annual dividends per share
Cash distributions grouped by calendar year; partial years are marked.
¥38.00
2025 complete year+26.7% since 2021
2026 partial: ¥19.00
¥30.00
2,021
¥32.00
2,022
¥32.00
2,023
¥34.00
2,024
¥38.00
2,025
¥19.00
2,026*
* Partial calendar year in the available dividend history.
Corporate action history
| Action | Ex-dividend date | Details | Record date | Payment date |
|---|---|---|---|---|
DividendUpcoming | Sep 29, 2026 | ¥21.00Semi-Annual | Sep 30, 2026 | Sep 29, 2026 |
DividendUpcoming | Mar 30, 2027 | ¥21.00Semi-Annual | Mar 31, 2027 | Mar 30, 2027 |
Dividend | Mar 30, 2026 | ¥19.00Semi-Annual | Mar 31, 2026 | Jun 24, 2026 |
Dividend | Sep 29, 2025 | ¥19.00Semi-Annual | Sep 30, 2025 | Nov 28, 2025 |
Dividend | Mar 28, 2025 | ¥19.00Semi-Annual | Mar 31, 2025 | Jun 25, 2025 |
Dividend | Sep 27, 2024 | ¥17.00Semi-Annual | Sep 30, 2024 | Nov 29, 2024 |
Ex-dividend Sep 29, 2026
¥21.00
Semi-Annual
Record Sep 30, 2026 · Payment Sep 29, 2026
Ex-dividend Mar 30, 2027
¥21.00
Semi-Annual
Record Mar 31, 2027 · Payment Mar 30, 2027
Ex-dividend Mar 30, 2026
¥19.00
Semi-Annual
Record Mar 31, 2026 · Payment Jun 24, 2026
Ex-dividend Sep 29, 2025
¥19.00
Semi-Annual
Record Sep 30, 2025 · Payment Nov 28, 2025
Ex-dividend Mar 28, 2025
¥19.00
Semi-Annual
Record Mar 31, 2025 · Payment Jun 25, 2025
Ex-dividend Sep 27, 2024
¥17.00
Semi-Annual
Record Sep 30, 2024 · Payment Nov 29, 2024
4536.T peers
ETFs holding 4536.T
Funds reporting this stock among their holdings, ordered by reported position size.
iShares Core TOPIX ETF1475.T1.62B0.06%2.89T JPY0.05%¥417.7-0.07%
Vanguard Total International Stock ETFVXUS53.02M0.01%646.2B USD0.05%$87.71+0.78%
Vanguard FTSE Developed Markets ETFVEA35.39M0.01%315B USD0.03%$73.42+0.80%
iShares Core MSCI EAFE ETFIEFA27.17M0.01%195.14B USD0.07%$100.85+0.86%
iShares MSCI EAFE Small-Cap ETFSCZ12.77M0.10%13.28B USD0.40%$86.60+0.70%
iShares International Equity Factor ETFINTF10.3M0.28%3.76B USD0.16%$43.14+0.82%
Schwab International Equity ETFSCHF8.53M0.01%69.7B USD0.03%$28.46+0.85%
Vanguard FTSE All-World ex-US ETFVEU8.37M0.01%95.9B USD0.04%$85.69+0.82%
iShares Core TOPIX ETF1475.T- Market value
- 1.62B
- Weight
- 0.06%
- AUM
- 2.89T JPY
- Expense ratio
- 0.05%
- Price / 1D
- ¥417.7-0.07%
Vanguard Total International Stock ETFVXUS- Market value
- 53.02M
- Weight
- 0.01%
- AUM
- 646.2B USD
- Expense ratio
- 0.05%
- Price / 1D
- $87.71+0.78%
Vanguard FTSE Developed Markets ETFVEA- Market value
- 35.39M
- Weight
- 0.01%
- AUM
- 315B USD
- Expense ratio
- 0.03%
- Price / 1D
- $73.42+0.80%
iShares Core MSCI EAFE ETFIEFA- Market value
- 27.17M
- Weight
- 0.01%
- AUM
- 195.14B USD
- Expense ratio
- 0.07%
- Price / 1D
- $100.85+0.86%
iShares MSCI EAFE Small-Cap ETFSCZ- Market value
- 12.77M
- Weight
- 0.10%
- AUM
- 13.28B USD
- Expense ratio
- 0.40%
- Price / 1D
- $86.60+0.70%
iShares International Equity Factor ETFINTF- Market value
- 10.3M
- Weight
- 0.28%
- AUM
- 3.76B USD
- Expense ratio
- 0.16%
- Price / 1D
- $43.14+0.82%
Schwab International Equity ETFSCHF- Market value
- 8.53M
- Weight
- 0.01%
- AUM
- 69.7B USD
- Expense ratio
- 0.03%
- Price / 1D
- $28.46+0.85%
Vanguard FTSE All-World ex-US ETFVEU- Market value
- 8.37M
- Weight
- 0.01%
- AUM
- 95.9B USD
- Expense ratio
- 0.04%
- Price / 1D
- $85.69+0.82%
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