Santen Pharmaceutical Co., Ltd. logo

Santen Pharmaceutical Co., Ltd.

4536.T

JPXHealthcareDrug Manufacturers - General

Latest quote

¥1,874.5

−¥5.00 · -0.27%

Aug 24, 3:30 PM JST

4536.T company overview

Regular session · JST · Market data may be delayed.

Company profile

Company website

Santen Pharmaceutical Co., Ltd. is a global enterprise engaged in the research, development, manufacturing, and marketing of both pharmaceutical products and medical devices. The company's primary focus lies in ophthalmic solutions, addressing a variety of eye conditions. Its pipeline for glaucoma and ocular hypertension includes several key assets: DE-111, currently in Phase III clinical trials; DE-117, available for sale in Japan; DE-126, progressing through Phase IIb trials; DE-128, which is on the market in Europe and undergoing Phase II/III trials in the United States; and DE-130A, also in Phase III development. Beyond glaucoma, Santen's offerings extend to other ocular ailments. It provides DE-114A for allergic conjunctivitis and DE-076C for vernal keratoconjunctivitis. Furthermore, DE-109 is in Phase III clinical trials for the treatment of uveitis. The company is also active in addressing myopia with DE-127, currently in Phase II/III trials in Japan and Phase III in other Asian markets, alongside STN1013400, which is in Phase I trials. For dry eye, Santen offers DE-089C, which has successfully concluded its Phase III clinical trials. In addition to its prescription portfolio, the company produces and sells various over-the-counter (OTC) pharmaceutical products. Founded in 1890 under the name Santendo Pharmaceutical Co., Ltd., the company rebranded to its current name, Santen Pharmaceutical Co., Ltd., in 1958. It is headquartered in Osaka, Japan.

Industry
Drug Manufacturers - General
Sector
Healthcare
Headquarters
JP
CEO
Takeshi Ito
Listed since
Jan 4, 2001
Employees
3,968

Market position

Day range

Current ¥1,874.5

52-week range

Current ¥1,874.5

Open
¥1,890
Previous close
¥1,879.5
Volume
871.9K
0.75× average
Average volume
1.16M
Average daily volume
Market cap
603B JPY
Beta
0.23
Market reference 1
50-day average
¥2,005.36
-6.53% below average
200-day average
¥1,782.48
+5.16% above average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
538.85B JPY
P/E (TTM)
15.74×
P/B (TTM)
2.01×
P/S (TTM)
2.07×
EV / EBITDA
7.95×
Earnings yield
6.39%
Free cash flow yield
6.27%
Dividend yield
2.03%

Profitability & efficiency

Gross margin
56.10%
Operating margin
15.67%
Net margin
13.25%
Return on equity
12.58%
Return on assets
8.83%
Return on invested capital
10.57%

Financial health

Debt / equity
0.1×
Current ratio
2.6×
Altman Z-score
5.37
Piotroski F-score
8 of 9

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends62%38%13%-12%Gross margin, FY2022: 55.15%Gross margin, FY2023: 56.11%Gross margin, FY2024: 54.27%Gross margin, FY2025: 54.40%Gross margin, FY2026: 55.20%Operating margin, FY2022: 13.51%Operating margin, FY2023: 11.47%Operating margin, FY2024: 17.19%Operating margin, FY2025: 18.74%Operating margin, FY2026: 15.50%Net margin, FY2022: 10.22%Net margin, FY2023: -5.36%Net margin, FY2024: 8.82%Net margin, FY2025: 12.09%Net margin, FY2026: 12.81%FY2022FY2023FY2024FY2025FY2026
Gross margin FY2022 55.15%. Gross margin FY2023 56.11%. Gross margin FY2024 54.27%. Gross margin FY2025 54.40%. Gross margin FY2026 55.20%. Operating margin FY2022 13.51%. Operating margin FY2023 11.47%. Operating margin FY2024 17.19%. Operating margin FY2025 18.74%. Operating margin FY2026 15.50%. Net margin FY2022 10.22%. Net margin FY2023 -5.36%. Net margin FY2024 8.82%. Net margin FY2025 12.09%. Net margin FY2026 12.81%.

Income trends

Revenue

291.62B JPY-2.79%

Operating income

45.22B JPY-19.59%

Net income

37.37B JPY+3.07%
Income trends across reported periods333.66B JPY206.89B JPY80.13B JPY−46.64B JPYRevenue, FY2022: 266.26B JPYRevenue, FY2023: 279.04B JPYRevenue, FY2024: 301.97B JPYRevenue, FY2025: 300B JPYRevenue, FY2026: 291.62B JPYOperating income, FY2022: 35.98B JPYOperating income, FY2023: 32.02B JPYOperating income, FY2024: 51.9B JPYOperating income, FY2025: 56.23B JPYOperating income, FY2026: 45.22B JPYNet income, FY2022: 27.22B JPYNet income, FY2023: −14.95B JPYNet income, FY2024: 26.64B JPYNet income, FY2025: 36.26B JPYNet income, FY2026: 37.37B JPYFY2022FY2023FY2024FY2025FY2026
Revenue FY2022 266.26B JPY. Revenue FY2023 279.04B JPY. Revenue FY2024 301.97B JPY. Revenue FY2025 300B JPY. Revenue FY2026 291.62B JPY. Operating income FY2022 35.98B JPY. Operating income FY2023 32.02B JPY. Operating income FY2024 51.9B JPY. Operating income FY2025 56.23B JPY. Operating income FY2026 45.22B JPY. Net income FY2022 27.22B JPY. Net income FY2023 −14.95B JPY. Net income FY2024 26.64B JPY. Net income FY2025 36.26B JPY. Net income FY2026 37.37B JPY.
Metric (JPY)FY2026FY2025FY2024FY2023FY2022
Revenue291.62B JPY300B JPY301.97B JPY279.04B JPY266.26B JPY
Cost of goods sold130.65B JPY136.8B JPY138.09B JPY122.47B JPY119.41B JPY
Gross profit160.97B JPY163.21B JPY163.88B JPY156.57B JPY146.85B JPY
Research and development26.19B JPY23.47B JPY24.7B JPY28.3B JPY26.38B JPY
Selling, general, and administrative89.57B JPY83.51B JPY87.27B JPY96.26B JPY84.5B JPY
Operating expenses115.76B JPY106.98B JPY111.97B JPY124.55B JPY110.88B JPY
Interest income1.64B JPY1.05B JPY619M JPY469M JPY402M JPY
Interest expense1.99B JPY1.08B JPY831M JPY486M JPY250M JPY
Depreciation and amortization18.36B JPY17.95B JPY18.18B JPY17.25B JPY17.06B JPY
Operating income45.22B JPY56.23B JPY51.9B JPY32.02B JPY35.98B JPY
Net income37.37B JPY36.26B JPY26.64B JPY−14.95B JPY27.22B JPY

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
73%
8 beats, 3 misses, 0 met estimates
Average EPS surprise
+5.73%
11 comparable reports
Latest EPS result
22.38
Estimate 21.27 · Beat by 5.22%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates50.3338.526.6814.85Q1 '25BeatQ2 '25BeatQ3 '25MissQ4 '25BeatQ1 '26MissQ2 '26BeatQ3 '26BeatQ4 '26Estimate
Q1 2025, reported Feb 6, 2025: actual 25.33, estimate 24.24, surprise +4.50%, Beat. Q2 2025, reported May 13, 2025: actual 25.77, estimate 17.3, surprise +48.96%, Beat. Q3 2025, reported Aug 7, 2025: actual 17.32, estimate 23.9, surprise -27.53%, Miss. Q4 2025, reported Nov 6, 2025: actual 24.44, estimate 20.89, surprise +16.99%, Beat. Q1 2026, reported Feb 5, 2026: actual 24.4, estimate 29.29, surprise -16.70%, Miss. Q2 2026, reported May 12, 2026: actual 47.88, estimate 30.79, surprise +55.51%, Beat. Q3 2026, reported Aug 6, 2026: actual 22.38, estimate 21.27, surprise +5.22%, Beat. Q4 2026, reported Nov 5, 2026: actual —, estimate 27.86, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates84.1B77.9B71.7B65.5BQ1 '25MissQ2 '25MissQ3 '25MissQ4 '25MissQ1 '26MissQ2 '26BeatQ3 '26MissQ4 '26Estimate
Q1 2025, reported Feb 6, 2025: actual 76.37B JPY, estimate 76.55B JPY, surprise -0.24%, Miss. Q2 2025, reported May 13, 2025: actual 77.23B JPY, estimate 78.7B JPY, surprise -1.86%, Miss. Q3 2025, reported Aug 7, 2025: actual 68.74B JPY, estimate 72.34B JPY, surprise -4.98%, Miss. Q4 2025, reported Nov 6, 2025: actual 69.14B JPY, estimate 69.63B JPY, surprise -0.69%, Miss. Q1 2026, reported Feb 5, 2026: actual 72.88B JPY, estimate 75.68B JPY, surprise -3.70%, Miss. Q2 2026, reported May 12, 2026: actual 80.86B JPY, estimate 76.98B JPY, surprise +5.04%, Beat. Q3 2026, reported Aug 6, 2026: actual 68.96B JPY, estimate 70.38B JPY, surprise -2.03%, Miss. Q4 2026, reported Nov 5, 2026: actual —, estimate 72.81B JPY, surprise —, Comparison unavailable.

Corporate actions

Annual dividends per share

Cash distributions grouped by calendar year; partial years are marked.

¥38.00

2025 complete year+26.7% since 2021

2026 partial: ¥19.00

* Partial calendar year in the available dividend history.

Corporate action history

DividendUpcoming

Ex-dividend Sep 29, 2026

¥21.00

Semi-Annual

Record Sep 30, 2026 · Payment Sep 29, 2026

DividendUpcoming

Ex-dividend Mar 30, 2027

¥21.00

Semi-Annual

Record Mar 31, 2027 · Payment Mar 30, 2027

Dividend

Ex-dividend Mar 30, 2026

¥19.00

Semi-Annual

Record Mar 31, 2026 · Payment Jun 24, 2026

Dividend

Ex-dividend Sep 29, 2025

¥19.00

Semi-Annual

Record Sep 30, 2025 · Payment Nov 28, 2025

Dividend

Ex-dividend Mar 28, 2025

¥19.00

Semi-Annual

Record Mar 31, 2025 · Payment Jun 25, 2025

Dividend

Ex-dividend Sep 27, 2024

¥17.00

Semi-Annual

Record Sep 30, 2024 · Payment Nov 29, 2024

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