
Nxera Pharma Co., Ltd.
4565.TJPXHealthcareBiotechnology
Latest quote
¥1,098
−¥5.00 · -0.45%
4565.T company overview
Regular session · JST · Market data may be delayed.
Company profile
Company websiteNxera Pharma Co., Ltd., established in Tokyo, Japan, in 1990, is a biopharmaceutical enterprise focused on the discovery, development, and commercialization of pharmaceutical solutions. The company's operations extend across multiple international markets, including Japan, Switzerland, the United States, Bermuda, and the United Kingdom. Its array of commercially available products encompasses respiratory treatments like Ultibro/Breezhaler and Seebri/Breezhaler for chronic obstructive pulmonary disease, as well as Enerzair and Breezhaler to manage asthma. Other marketed therapeutics include ORAVI, a unique formulation addressing oropharyngeal candidiasis, and PIVLAZ, prescribed for cerebral vasospasm. The firm boasts a robust pipeline of investigational medicines, featuring HTL0039732 for immuno-oncology, HTL0048149 for schizophrenia, Daridorexant targeting insomnia, and HTL0016878 for both schizophrenia and other neuropsychiatric conditions. Additional compounds under development include PF-07081532 for Type 2 diabetes mellitus and obesity, PF-07054894 for inflammatory bowel disease, PF-07258669 for anorexia, and PF-06954522 for metabolic disorders. The pipeline also contains NBI-1117569 for various neurological diseases and NBI-1117570 for central nervous system ailments. Furthermore, Nxera Pharma is advancing a GPR35 agonist in the preclinical stage for inflammatory bowel disease and other gastrointestinal conditions, alongside other early-stage drug candidates. The company maintains significant strategic collaborations with industry leaders such as AbbVie, Biohaven, Genentech Inc., GSK, Pfizer Inc., Neurocrine Biosciences Inc., Novartis International AG, and Verily.
- Industry
- Biotechnology
- Sector
- Healthcare
- Headquarters
- JP
- CEO
- Christopher Cargill
- Listed since
- Jul 29, 2004
- Employees
- 354
Market position
Day range
Current ¥1,098
52-week range
Current ¥1,098
- Open
- ¥1,110
- Previous close
- ¥1,103
- Volume
- 580K
- 0.64× average
- Average volume
- 902.83K
- Average daily volume
- Market cap
- 100.72B JPY
- Beta
- 0.22
- Market reference 1
- 50-day average
- ¥957.5
- +14.67% above average
- 200-day average
- ¥928.11
- +18.30% above average
Financials
Financial snapshot
Latest / TTMValuation & yield
- Enterprise value
- 111.67B JPY
- P/E (TTM)
- -12.71×
- P/B (TTM)
- 1.55×
- P/S (TTM)
- 3.01×
- EV / EBITDA
- -28.58×
- Earnings yield
- -16.78%
- Free cash flow yield
- -4.17%
- Dividend yield
- 0.00%
Profitability & efficiency
- Gross margin
- 76.05%
- Operating margin
- -6.52%
- Net margin
- -23.34%
- Return on equity
- -20.54%
- Return on assets
- -9.30%
- Return on invested capital
- -5.59%
Financial health
- Debt / equity
- 0.84×
- Current ratio
- 2.54×
- Altman Z-score
- 1.17
- Piotroski F-score
- 4 of 9
Financial statements
Margin trends
Profitability as a percentage of reported revenue.
Income trends
Revenue
Operating income
Net income
| Metric (JPY) | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 |
|---|---|---|---|---|---|
| Revenue | 29.62B JPY | 28.84B JPY | 12.77B JPY | 15.57B JPY | 17.71B JPY |
| Cost of goods sold | 8.2B JPY | 10.71B JPY | 4.9B JPY | 1.77B JPY | 1.74B JPY |
| Gross profit | 21.42B JPY | 18.13B JPY | 7.87B JPY | 13.8B JPY | 15.98B JPY |
| Research and development | 14.47B JPY | 11.82B JPY | 10.08B JPY | 7.45B JPY | 5.93B JPY |
| Selling, general, and administrative | 15.23B JPY | 11.68B JPY | 6.85B JPY | 3.54B JPY | 3.14B JPY |
| Operating expenses | 29.69B JPY | 23.49B JPY | 16.93B JPY | 10.99B JPY | 9.07B JPY |
| Interest income | 987M JPY | 1.48B JPY | 1.23B JPY | 236M JPY | 4M JPY |
| Interest expense | 7.48B JPY | 777M JPY | 803M JPY | 715M JPY | 528M JPY |
| Depreciation and amortization | 4.37B JPY | 3.98B JPY | 2.48B JPY | 1.35B JPY | 1.28B JPY |
| Operating income | −8.27B JPY | −5.36B JPY | −9.06B JPY | 2.81B JPY | 6.91B JPY |
| Net income | −12.53B JPY | −4.84B JPY | −7.19B JPY | 382M JPY | 1.02B JPY |
Company facts updated Aug 24, 2026.
Earnings
- EPS beat rate
- 30%
- 3 beats, 7 misses, 0 met estimates
- Average EPS surprise
- -175.31%
- 10 comparable reports
- Latest EPS result
- -2.22
- Estimate -3.43 · Beat by 35.33%
EPS: actual versus estimate
Recent quarterly results
Revenue: actual versus estimate
Recent quarterly results
Corporate actions
Corporate action history
| Action | Ex-dividend date | Details | Record date | Payment date |
|---|---|---|---|---|
Dividend | Mar 27, 2015 | ¥10.00Special | — | — |
Ex-dividend Mar 27, 2015
¥10.00
Special
4565.T peers
ETFs holding 4565.T
Funds reporting this stock among their holdings, ordered by reported position size.
iShares Core TOPIX ETF1475.T276.3M0.01%2.89T JPY0.05%¥417.7-0.07%
Vanguard Total International Stock ETFVXUS5.81M0.00%646.2B USD0.05%$87.71+0.78%
iShares Core MSCI EAFE ETFIEFA3.83M0.00%195.14B USD0.07%$100.85+0.86%
Vanguard FTSE Developed Markets ETFVEA3.79M0.00%315B USD0.03%$73.42+0.80%
Dimensional - International Small Cap ETFDFIS2.19M0.04%5.91B USD0.39%$37.545+0.71%
iShares MSCI EAFE Small-Cap ETFSCZ1.85M0.01%13.28B USD0.40%$86.60+0.70%
Vanguard FTSE All-World ex-US Small-Cap ETFVSS1.39M0.01%13.6B USD0.06%$160.06+0.43%
Schwab International Small-Cap Equity ETFSCHC1.03M0.02%5.73B USD0.06%$51.25+0.61%
iShares Core TOPIX ETF1475.T- Market value
- 276.3M
- Weight
- 0.01%
- AUM
- 2.89T JPY
- Expense ratio
- 0.05%
- Price / 1D
- ¥417.7-0.07%
Vanguard Total International Stock ETFVXUS- Market value
- 5.81M
- Weight
- 0.00%
- AUM
- 646.2B USD
- Expense ratio
- 0.05%
- Price / 1D
- $87.71+0.78%
iShares Core MSCI EAFE ETFIEFA- Market value
- 3.83M
- Weight
- 0.00%
- AUM
- 195.14B USD
- Expense ratio
- 0.07%
- Price / 1D
- $100.85+0.86%
Vanguard FTSE Developed Markets ETFVEA- Market value
- 3.79M
- Weight
- 0.00%
- AUM
- 315B USD
- Expense ratio
- 0.03%
- Price / 1D
- $73.42+0.80%
Dimensional - International Small Cap ETFDFIS- Market value
- 2.19M
- Weight
- 0.04%
- AUM
- 5.91B USD
- Expense ratio
- 0.39%
- Price / 1D
- $37.545+0.71%
iShares MSCI EAFE Small-Cap ETFSCZ- Market value
- 1.85M
- Weight
- 0.01%
- AUM
- 13.28B USD
- Expense ratio
- 0.40%
- Price / 1D
- $86.60+0.70%
Vanguard FTSE All-World ex-US Small-Cap ETFVSS- Market value
- 1.39M
- Weight
- 0.01%
- AUM
- 13.6B USD
- Expense ratio
- 0.06%
- Price / 1D
- $160.06+0.43%
Schwab International Small-Cap Equity ETFSCHC- Market value
- 1.03M
- Weight
- 0.02%
- AUM
- 5.73B USD
- Expense ratio
- 0.06%
- Price / 1D
- $51.25+0.61%
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