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Carna Biosciences, Inc. logo

Carna Biosciences, Inc.

4572.T

JPXHealthcareBiotechnology

Open in GoAI

Latest quote

¥408

+¥5.00 · +1.24%

Aug 24, 3:30 PM JST

4572.T company overview

Regular session · JST · Market data may be delayed.

Company profile

Industry
Biotechnology
Sector
Healthcare
Headquarters
JP

Market position

Day range

Current ¥408

52-week range

Current ¥408

Open
¥419
Previous close
¥403
Volume
136.9K
Market cap
7.83B JPY
50-day average
¥333.96
+22.17% above average
200-day average
¥352.93
+15.61% above average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
7B JPY
P/E (TTM)
-3.66×
P/B (TTM)
-20×
P/S (TTM)
10.74×
EV / EBITDA
-3.24×
Earnings yield
-31.92%
Free cash flow yield
-31.87%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
69.52%
Operating margin
-271.05%
Net margin
-295.59%
Return on equity
-702.25%
Return on assets
-176.59%
Return on invested capital
-192.40%

Financial health

Debt / equity
-4.87×
Current ratio
6.99×
Altman Z-score
-2.5
Piotroski F-score
4 of 9

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends140%-47%-235%-422%Gross margin, FY2021: 93.29%Gross margin, FY2022: 87.63%Gross margin, FY2023: 89.22%Gross margin, FY2024: 73.20%Gross margin, FY2025: 67.03%Operating margin, FY2021: -26.33%Operating margin, FY2022: -91.57%Operating margin, FY2023: -68.70%Operating margin, FY2024: -326.31%Operating margin, FY2025: -358.34%Net margin, FY2021: -26.49%Net margin, FY2022: -97.32%Net margin, FY2023: -70.91%Net margin, FY2024: -342.42%Net margin, FY2025: -375.00%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2021 93.29%. Gross margin FY2022 87.63%. Gross margin FY2023 89.22%. Gross margin FY2024 73.20%. Gross margin FY2025 67.03%. Operating margin FY2021 -26.33%. Operating margin FY2022 -91.57%. Operating margin FY2023 -68.70%. Operating margin FY2024 -326.31%. Operating margin FY2025 -358.34%. Net margin FY2021 -26.49%. Net margin FY2022 -97.32%. Net margin FY2023 -70.91%. Net margin FY2024 -342.42%. Net margin FY2025 -375.00%.

Income trends

Revenue

579.06M JPY-8.99%

Operating income

−2.07B JPY+0.05%

Net income

−2.17B JPY+0.33%
Income trends across reported periods2.44B JPY758.7M JPY−919.74M JPY−2.6B JPYRevenue, FY2021: 2.02B JPYRevenue, FY2022: 1.39B JPYRevenue, FY2023: 1.63B JPYRevenue, FY2024: 636.24M JPYRevenue, FY2025: 579.06M JPYOperating income, FY2021: −531.14M JPYOperating income, FY2022: −1.27B JPYOperating income, FY2023: −1.12B JPYOperating income, FY2024: −2.08B JPYOperating income, FY2025: −2.07B JPYNet income, FY2021: −534.47M JPYNet income, FY2022: −1.35B JPYNet income, FY2023: −1.15B JPYNet income, FY2024: −2.18B JPYNet income, FY2025: −2.17B JPYFY2021FY2022FY2023FY2024FY2025
Revenue FY2021 2.02B JPY. Revenue FY2022 1.39B JPY. Revenue FY2023 1.63B JPY. Revenue FY2024 636.24M JPY. Revenue FY2025 579.06M JPY. Operating income FY2021 −531.14M JPY. Operating income FY2022 −1.27B JPY. Operating income FY2023 −1.12B JPY. Operating income FY2024 −2.08B JPY. Operating income FY2025 −2.07B JPY. Net income FY2021 −534.47M JPY. Net income FY2022 −1.35B JPY. Net income FY2023 −1.15B JPY. Net income FY2024 −2.18B JPY. Net income FY2025 −2.17B JPY.
Metric (JPY)FY2025FY2024FY2023FY2022FY2021
Revenue579.06M JPY636.24M JPY1.63B JPY1.39B JPY2.02B JPY
Cost of goods sold190.91M JPY170.54M JPY175.29M JPY171.55M JPY135.39M JPY
Gross profit388.15M JPY465.69M JPY1.45B JPY1.22B JPY1.88B JPY
Research and development1.85B JPY1.89B JPY1.9B JPY1.88B JPY1.84B JPY
Selling, general, and administrative2.46B JPY654.89M JPY663.72M JPY602.77M JPY571.42M JPY
Operating expenses2.46B JPY2.54B JPY2.57B JPY2.49B JPY2.41B JPY
Interest income3.88M JPY14.5M JPY170K JPY147K JPY107K JPY
Interest expense52M JPY2.96M JPY3.45M JPY5.31M JPY3.93M JPY
Depreciation and amortization—31.25M JPY35.61M JPY33.81M JPY19.16M JPY
Operating income−2.07B JPY−2.08B JPY−1.12B JPY−1.27B JPY−531.14M JPY
Net income−2.17B JPY−2.18B JPY−1.15B JPY−1.35B JPY−534.47M JPY

Company facts updated Aug 24, 2026.

Earnings

Latest EPS result
-26.35

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Estimates unavailable
Quarterly EPS actual values compared with estimates-24.89-27.36-29.84-32.31Q4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26Q2 '26Q3 '26
Q4 2024, reported Nov 8, 2024: actual -27.39, estimate —, surprise —, Comparison unavailable. Q1 2025, reported Feb 10, 2025: actual -31.07, estimate —, surprise —, Comparison unavailable. Q2 2025, reported May 9, 2025: actual -26.13, estimate —, surprise —, Comparison unavailable. Q3 2025, reported Aug 12, 2025: actual -29.16, estimate —, surprise —, Comparison unavailable. Q4 2025, reported Nov 7, 2025: actual -28.47, estimate —, surprise —, Comparison unavailable. Q1 2026, reported Feb 10, 2026: actual -29.86, estimate —, surprise —, Comparison unavailable. Q2 2026, reported May 8, 2026: actual -26.78, estimate —, surprise —, Comparison unavailable. Q3 2026, reported Aug 6, 2026: actual -26.35, estimate —, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Estimates unavailable
Quarterly Revenue actual values compared with estimates226.82M184.19M141.56M98.93MQ4 '24Q1 '25Q2 '25Q3 '25Q4 '25Q1 '26Q2 '26Q3 '26
Q4 2024, reported Nov 8, 2024: actual 172.22M JPY, estimate —, surprise —, Comparison unavailable. Q1 2025, reported Feb 10, 2025: actual 149.02M JPY, estimate —, surprise —, Comparison unavailable. Q2 2025, reported May 9, 2025: actual 143.35M JPY, estimate —, surprise —, Comparison unavailable. Q3 2025, reported Aug 12, 2025: actual 107.75M JPY, estimate —, surprise —, Comparison unavailable. Q4 2025, reported Nov 7, 2025: actual 144.33M JPY, estimate —, surprise —, Comparison unavailable. Q1 2026, reported Feb 10, 2026: actual 184M JPY, estimate —, surprise —, Comparison unavailable. Q2 2026, reported May 8, 2026: actual 183M JPY, estimate —, surprise —, Comparison unavailable. Q3 2026, reported Aug 6, 2026: actual 218M JPY, estimate —, surprise —, Comparison unavailable.

Corporate actions

Corporate action history

Stock split

Effective Dec 26, 2013

100:1

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