Chiome Bioscience Inc. logo

Chiome Bioscience Inc.

4583.T

JPXHealthcareBiotechnology

Latest quote

¥83.00

−¥1.00 · -1.19%

Aug 24, 2:31 PM JSTData delayed

4583.T company overview

Regular session · JST · Market data may be delayed.

Company profile

Company website

Chiome Bioscience Inc. engages in the research and development of drug discovery technology platforms worldwide. It operates in two segments, Drug Discovery Business and Drug Discovery Support Business. The company offers ADLib System, a technology for generating monoclonal antibodies which is used to generate antibodies for drug discovery research; and Human ADLib System, which converts chicken antibody genes to humanized antibodies. It also provides protein expression and purification services; stable cell line development services for recombinant protein and antibody production; and antibody generation services using the ADLib system. In addition, the company's product pipeline under Phase 1 trial comprises ADCT-701, an anti-dlk1 antibody for treating liver cancer; CBA-1205, an afucosylated anti-dlk1 antibody for liver cancer, lung cancer, and neuroblastoma; and CBA-1535, an anti 5T4/WAIF1 antibody for malignant mesothelioma, small cell lung cancer, non-small cell lung cancer, and triple negative breast cancer (TNBC). Further, its product pipeline under preclinical study includes PCDC, an anti- CDCP1 antibody for lung, colorectal, pancreatic, breast, and ovarian tumors; PTRY, an antibody 5T4/CD3/PD-L1 for treating malignant mesothelioma, small cell lung cancer, non-small cell lung cancer, and TNBC; BMAA, an anti-semphorin3a antibody for treating renal and other diseases; LIV-2008/2008b, an anti-TROP-2 antibody for the treatment of TNBC, lung cancer, and colorectal cancer; PFKR, an anti-CX3CR1 antibody for secondary progressive multiple sclerosis; and PXLR, an anti-CXCL1/2/3/5 antibody for the treatment of gastric, breast, and ovarian tumors. Chiome Bioscience Inc. was incorporated in 2005 and is headquartered in Tokyo, Japan.

Industry
Biotechnology
Sector
Healthcare
Headquarters
JP
CEO
Masamichi Koike
Listed since
Dec 20, 2011
Employees
49

Market position

Day range

Current ¥83.00

52-week range

Current ¥83.00

Open
¥84.00
Previous close
¥84.00
Volume
290.6K
0.44× average
Average volume
656.71K
Average daily volume
Market cap
6.03B JPY
Beta
1.87
Market reference 1
50-day average
¥72.78
+14.04% above average
200-day average
¥98.22
-15.50% below average

Financials

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends87%-20%-127%-234%Gross margin, FY2021: 58.99%Gross margin, FY2022: 55.13%Gross margin, FY2023: 58.28%Gross margin, FY2024: 55.33%Gross margin, FY2025: 59.93%Operating margin, FY2021: -187.16%Operating margin, FY2022: -199.53%Operating margin, FY2023: -176.59%Operating margin, FY2024: -132.03%Operating margin, FY2025: -165.14%Net margin, FY2021: -207.58%Net margin, FY2022: -197.03%Net margin, FY2023: -178.77%Net margin, FY2024: -130.73%Net margin, FY2025: -165.65%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2021 58.99%. Gross margin FY2022 55.13%. Gross margin FY2023 58.28%. Gross margin FY2024 55.33%. Gross margin FY2025 59.93%. Operating margin FY2021 -187.16%. Operating margin FY2022 -199.53%. Operating margin FY2023 -176.59%. Operating margin FY2024 -132.03%. Operating margin FY2025 -165.14%. Net margin FY2021 -207.58%. Net margin FY2022 -197.03%. Net margin FY2023 -178.77%. Net margin FY2024 -130.73%. Net margin FY2025 -165.65%.

Income trends

Revenue

593.29M JPY-24.02%

Operating income

−979.78M JPY+4.96%

Net income

−982.78M JPY+3.72%
Income trends across reported periods1.01B JPY102.6M JPY−801.68M JPY−1.71B JPYRevenue, FY2021: 712.93M JPYRevenue, FY2022: 630.82M JPYRevenue, FY2023: 682.46M JPYRevenue, FY2024: 780.81M JPYRevenue, FY2025: 593.29M JPYOperating income, FY2021: −1.33B JPYOperating income, FY2022: −1.26B JPYOperating income, FY2023: −1.21B JPYOperating income, FY2024: −1.03B JPYOperating income, FY2025: −979.78M JPYNet income, FY2021: −1.48B JPYNet income, FY2022: −1.24B JPYNet income, FY2023: −1.22B JPYNet income, FY2024: −1.02B JPYNet income, FY2025: −982.78M JPYFY2021FY2022FY2023FY2024FY2025
Revenue FY2021 712.93M JPY. Revenue FY2022 630.82M JPY. Revenue FY2023 682.46M JPY. Revenue FY2024 780.81M JPY. Revenue FY2025 593.29M JPY. Operating income FY2021 −1.33B JPY. Operating income FY2022 −1.26B JPY. Operating income FY2023 −1.21B JPY. Operating income FY2024 −1.03B JPY. Operating income FY2025 −979.78M JPY. Net income FY2021 −1.48B JPY. Net income FY2022 −1.24B JPY. Net income FY2023 −1.22B JPY. Net income FY2024 −1.02B JPY. Net income FY2025 −982.78M JPY.
Metric (JPY)FY2025FY2024FY2023FY2022FY2021
Revenue593.29M JPY780.81M JPY682.46M JPY630.82M JPY712.93M JPY
Cost of goods sold237.71M JPY348.78M JPY284.75M JPY283.03M JPY292.34M JPY
Gross profit355.58M JPY432.03M JPY397.72M JPY347.78M JPY420.59M JPY
Research and development776.54M JPY935.91M JPY1.05B JPY1.13B JPY1.31B JPY
Selling, general, and administrative558.82M JPY526.98M JPY551.86M JPY471.9M JPY444.59M JPY
Operating expenses1.34B JPY1.46B JPY1.6B JPY1.61B JPY1.75B JPY
Interest income2.46M JPY215K JPY19K JPY21K JPY29K JPY
Interest expense3.16M JPY2.87M JPY2.07M JPY1.32M JPY1.32M JPY
Depreciation and amortization3.74M JPY1.17M JPY1.2M JPY1.48M JPY2.96M JPY
Operating income−979.78M JPY−1.03B JPY−1.21B JPY−1.26B JPY−1.33B JPY
Net income−982.78M JPY−1.02B JPY−1.22B JPY−1.24B JPY−1.48B JPY

Company facts updated Aug 24, 2026.

Corporate actions

Corporate action history

Stock split

Effective Mar 27, 2014

2:1

Stock split

Effective Jun 26, 2013

2:1

Stock split

Effective Mar 28, 2012

2:1

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