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PeptiDream Inc. logo

PeptiDream Inc.

4587.T

JPXHealthcareBiotechnology

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Latest quote

¥1,099.5

−¥15.00 · -1.35%

Aug 24, 3:30 PM JST

4587.T company overview

Regular session · JST · Market data may be delayed.

Company profile

Company website

PeptiDream Inc. functions as a biopharmaceutical enterprise, concentrating on the identification and progression of therapeutic compounds such as constrained peptides, small molecules, and peptide-drug conjugates. The company's unique product pipeline is underpinned by its proprietary Peptide Discovery Platform System (PDPS), an advanced technology specifically designed for the development of peptide-based drugs. Additionally, PeptiDream maintains an exclusive licensing and collaborative research partnership with Takeda Pharmaceutical Company Limited, aimed at creating peptide drug conjugates for the treatment of neuromuscular conditions. Established in 2006, the company's primary offices are situated in Kawasaki, Japan.

Industry
Biotechnology
Sector
Healthcare
Headquarters
JP
CEO
Patrick Crawford Reid
Listed since
Jun 12, 2013
Employees
745

Market position

Day range

Current ¥1,099.5

52-week range

Current ¥1,099.5

Open
¥1,126
Previous close
¥1,114.5
Volume
1.05M
1.07× average
Average volume
986.75K
Average daily volume
Market cap
141.28B JPY
Beta
0.35
Market reference 1
50-day average
¥993.95
+10.62% above average
200-day average
¥1,308.86
-16.00% below average

Financials

Financial snapshot

Latest / TTM

Valuation & yield

Enterprise value
202.55B JPY
P/E (TTM)
-39.11×
P/B (TTM)
2.91×
P/S (TTM)
7.36×
EV / EBITDA
-75.43×
Earnings yield
-1.75%
Free cash flow yield
-6.97%
Dividend yield
0.00%

Profitability & efficiency

Gross margin
43.35%
Operating margin
-25.34%
Net margin
-18.88%
Return on equity
-7.28%
Return on assets
-4.87%
Return on invested capital
-4.97%

Financial health

Debt / equity
0.32×
Current ratio
1.66×

Financial statements

Margin trends

Profitability as a percentage of reported revenue.

Gross marginOperating marginNet margin
Gross, operating, and net margin trends84%44%3%-37%Gross margin, FY2021: 73.85%Gross margin, FY2022: 66.34%Gross margin, FY2023: 58.73%Gross margin, FY2024: 73.17%Gross margin, FY2025: 40.61%Operating margin, FY2021: 42.95%Operating margin, FY2022: 34.80%Operating margin, FY2023: 24.99%Operating margin, FY2024: 45.83%Operating margin, FY2025: -26.86%Net margin, FY2021: 27.31%Net margin, FY2022: 28.13%Net margin, FY2023: 10.57%Net margin, FY2024: 32.17%Net margin, FY2025: -20.24%FY2021FY2022FY2023FY2024FY2025
Gross margin FY2021 73.85%. Gross margin FY2022 66.34%. Gross margin FY2023 58.73%. Gross margin FY2024 73.17%. Gross margin FY2025 40.61%. Operating margin FY2021 42.95%. Operating margin FY2022 34.80%. Operating margin FY2023 24.99%. Operating margin FY2024 45.83%. Operating margin FY2025 -26.86%. Net margin FY2021 27.31%. Net margin FY2022 28.13%. Net margin FY2023 10.57%. Net margin FY2024 32.17%. Net margin FY2025 -20.24%.

Income trends

Revenue

18.52B JPY-60.32%

Operating income

−4.97B JPY−26.37B JPY

Net income

−3.75B JPY−18.76B JPY
Income trends across reported periods51.84B JPY31.18B JPY10.52B JPY−10.14B JPYRevenue, FY2021: 9.42B JPYRevenue, FY2022: 26.85B JPYRevenue, FY2023: 28.71B JPYRevenue, FY2024: 46.68B JPYRevenue, FY2025: 18.52B JPYOperating income, FY2021: 4.05B JPYOperating income, FY2022: 9.35B JPYOperating income, FY2023: 7.18B JPYOperating income, FY2024: 21.39B JPYOperating income, FY2025: −4.97B JPYNet income, FY2021: 2.57B JPYNet income, FY2022: 7.55B JPYNet income, FY2023: 3.04B JPYNet income, FY2024: 15.01B JPYNet income, FY2025: −3.75B JPYFY2021FY2022FY2023FY2024FY2025
Revenue FY2021 9.42B JPY. Revenue FY2022 26.85B JPY. Revenue FY2023 28.71B JPY. Revenue FY2024 46.68B JPY. Revenue FY2025 18.52B JPY. Operating income FY2021 4.05B JPY. Operating income FY2022 9.35B JPY. Operating income FY2023 7.18B JPY. Operating income FY2024 21.39B JPY. Operating income FY2025 −4.97B JPY. Net income FY2021 2.57B JPY. Net income FY2022 7.55B JPY. Net income FY2023 3.04B JPY. Net income FY2024 15.01B JPY. Net income FY2025 −3.75B JPY.
Metric (JPY)FY2025FY2024FY2023FY2022FY2021
Revenue18.52B JPY46.68B JPY28.71B JPY26.85B JPY9.42B JPY
Cost of goods sold11B JPY12.52B JPY11.85B JPY9.04B JPY2.46B JPY
Gross profit7.52B JPY34.16B JPY16.86B JPY17.81B JPY6.96B JPY
Research and development5.02B JPY4B JPY3.16B JPY2.92B JPY1.65B JPY
Selling, general, and administrative7.47B JPY8.59B JPY6.67B JPY5.83B JPY2.59B JPY
Operating expenses12.5B JPY12.76B JPY9.69B JPY8.47B JPY2.91B JPY
Interest income242.61M JPY15.84M JPY6.17M JPY1.33M JPY283K JPY
Interest expense500.31M JPY288.06M JPY231.86M JPY190.09M JPY—
Depreciation and amortization2.13B JPY2.25B JPY2.43B JPY1.97B JPY633.01M JPY
Operating income−4.97B JPY21.39B JPY7.18B JPY9.35B JPY4.05B JPY
Net income−3.75B JPY15.01B JPY3.04B JPY7.55B JPY2.57B JPY

Company facts updated Aug 24, 2026.

Earnings

EPS beat rate
36%
4 beats, 7 misses, 0 met estimates
Average EPS surprise
-146.38%
11 comparable reports
Latest EPS result
-8.71
Estimate -3.13 · Miss by 178.68%

EPS: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly EPS actual values compared with estimates12.610.9-10.81-22.52Q1 '25MissQ2 '25MissQ3 '25MissQ4 '25MissQ1 '26BeatQ2 '26BeatQ3 '26MissQ4 '26Estimate
Q1 2025, reported Feb 12, 2025: actual -20.1, estimate -8.88, surprise -126.26%, Miss. Q2 2025, reported May 12, 2025: actual -7.97, estimate -4.57, surprise -74.40%, Miss. Q3 2025, reported Aug 6, 2025: actual -8.43, estimate 10.19, surprise -182.73%, Miss. Q4 2025, reported Nov 12, 2025: actual -8.48, estimate -7.58, surprise -11.87%, Miss. Q1 2026, reported Feb 16, 2026: actual -4.11, estimate -5.69, surprise +27.83%, Beat. Q2 2026, reported May 13, 2026: actual -6.62, estimate -8.05, surprise +17.76%, Beat. Q3 2026, reported Aug 12, 2026: actual -8.71, estimate -3.13, surprise -178.68%, Miss. Q4 2026, reported Nov 5, 2026: actual —, estimate -7.01, surprise —, Comparison unavailable.

Revenue: actual versus estimate

Recent quarterly results

ActualEstimate
Quarterly Revenue actual values compared with estimates8.36B6.88B5.39B3.91BQ1 '25MissQ2 '25MissQ3 '25MissQ4 '25MissQ1 '26MissQ2 '26BeatQ3 '26MissQ4 '26Estimate
Q1 2025, reported Feb 12, 2025: actual 5.07B JPY, estimate 5.42B JPY, surprise -6.48%, Miss. Q2 2025, reported May 12, 2025: actual 4.23B JPY, estimate 5.01B JPY, surprise -15.45%, Miss. Q3 2025, reported Aug 6, 2025: actual 4.31B JPY, estimate 8.04B JPY, surprise -46.39%, Miss. Q4 2025, reported Nov 12, 2025: actual 4.31B JPY, estimate 4.59B JPY, surprise -5.91%, Miss. Q1 2026, reported Feb 16, 2026: actual 5.66B JPY, estimate 6B JPY, surprise -5.58%, Miss. Q2 2026, reported May 13, 2026: actual 4.76B JPY, estimate 4.54B JPY, surprise +4.93%, Beat. Q3 2026, reported Aug 12, 2026: actual 4.46B JPY, estimate 5.68B JPY, surprise -21.38%, Miss. Q4 2026, reported Nov 5, 2026: actual —, estimate 5.06B JPY, surprise —, Comparison unavailable.

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ETFs holding 4587.T

Funds reporting this stock among their holdings, ordered by reported position size.

iShares Core TOPIX ETF logoiShares Core TOPIX ETF1475.T
Market value
307.71M
Weight
0.01%
AUM
2.89T JPY
Expense ratio
0.05%
Price / 1D
¥417.7-0.07%
iShares JPX-Nikkei 400 ETF logoiShares JPX-Nikkei 400 ETF1364.T
Market value
88.94M
Weight
0.01%
AUM
592.34B JPY
Expense ratio
0.05%
Price / 1D
¥3,7610.00%
Vanguard Total International Stock ETF logoVanguard Total International Stock ETFVXUS
Market value
8.28M
Weight
0.00%
AUM
646.2B USD
Expense ratio
0.05%
Price / 1D
$87.1542-0.63%
iShares Core MSCI EAFE ETF logoiShares Core MSCI EAFE ETFIEFA
Market value
5.78M
Weight
0.00%
AUM
195.14B USD
Expense ratio
0.07%
Price / 1D
$100.64-0.21%
Vanguard FTSE Developed Markets ETF logoVanguard FTSE Developed Markets ETFVEA
Market value
5.54M
Weight
0.00%
AUM
315B USD
Expense ratio
0.03%
Price / 1D
$73.075-0.47%
OneAscent International Equity ETF logoOneAscent International Equity ETFOAIM
Market value
4.19M
Weight
1.83%
AUM
358.82M USD
Expense ratio
0.89%
Price / 1D
$47.8237-0.62%
Vanguard FTSE All-World ex-US Small-Cap ETF logoVanguard FTSE All-World ex-US Small-Cap ETFVSS
Market value
2.57M
Weight
0.02%
AUM
13.6B USD
Expense ratio
0.06%
Price / 1D
$159.13-0.58%
iShares MSCI EAFE Small-Cap ETF logoiShares MSCI EAFE Small-Cap ETFSCZ
Market value
2.42M
Weight
0.02%
AUM
13.28B USD
Expense ratio
0.40%
Price / 1D
$86.51-0.10%

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